14,590 research outputs found

    The cost of systemic corticosteroid-induced morbidity in severe asthma : a health economic analysis

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    The study data-set was supported by the Respiratory Effectiveness Group through their academic partnership with Optimum Patient Care. Ciaran O'Neill was funded under a HRB Research Leader Award (RL/13/16).Peer reviewedPublisher PD

    The Importance of Recruitment in Job Choice: A Different Way of Looking

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    Recent literature reviews have called into question the impact of recruitment activities on applicants\u27 job choices. However, most previous findings have been based on cross-sectional ratings obtained immediately after initial screening interviews, thus raising questions about the degree to which prior conclusions are bound to that particuJar methodology. In contrast, the present study used longitudinal structured interviews to let job seekers explain, in their own words, how they made critical job search and choice decisions. Interview transcripts revealed that recruitment practices played a variety of roles in job seeker decisions. For example, consistent with signalling theory, subjects interpreted a wide variety of recruitment experiences (recruiter competence, sex composition of interview panels, recruitment delays) as symbolic of broader organizational characteristics. In addition, a number of contingency variables emerged that seemed to affect the perceived signalling value of recruitment experiences (e.g., prior knowledge of the company, functional area of the recruiter). Also notable were the strongly negative effects of recruitment delays, particularly among male students with higher grade point averages and greater job search success. Finally, our results suggest that certain applicant reactions may be systematically related to sex, work experience, grade point average, and search success. The article concludes with practical and research implications

    DREIDING: A generic force field for molecular simulations

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    We report the parameters for a new generic force field, DREIDING, that we find useful for predicting structures and dynamics of organic, biological, and main-group inorganic molecules. The philosophy in DREIDING is to use general force constants and geometry parameters based on simple hybridization considerations rather than individual force constants and geometric parameters that depend on the particular combination of atoms involved in the bond, angle, or torsion terms. Thus all bond distances are derived from atomic radii, and there is only one force constant each for bonds, angles, and inversions and only six different values for torsional barriers. Parameters are defined for all possible combinations of atoms and new atoms can be added to the force field rather simply. This paper reports the parameters for the "nonmetallic" main-group elements (B, C, N, 0, F columns for the C, Si, Ge, and Sn rows) plus H and a few metals (Na, Ca, Zn, Fe). The accuracy of the DREIDING force field is tested by comparing with (i) 76 accurately determined crystal structures of organic compounds involving H, C, N, 0, F, P, S, CI, and Br, (ii) rotational barriers of a number of molecules, and (iii) relative conformational energies and barriers of a number of molecules. We find excellent results for these systems

    Recruiter Perceptions of Applicant Fit: Commonalities and Differences

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    To date, normative selection models have focused primarily on matching individual knowledges, skills, and abilities to job requirements. However, it has increasingly been argued that people should also be selected for fit to broader organizational characteristics such as strategy, culture and values. Despite the apparent reasonableness of these claims, there has been little research on how employers actually go about the task of screening or selecting for broader organizational fit. Accordingly, the present study examined how organizational recruiters assess applicant fit. Fifty-four campus recruiters in four colleges provided examples of best-fitting and worst-fitting applicants from just-completed interview schedules, along with specific descriptions of what it was that made each applicant fit or not fit . Examination of interview transcripts suggested that despite the recent emphasis on unique organizational values, strategies, or cultures in discussions of fit, by far the most frequently-mentioned determinants of fit were either (1) job-related coursework or experience, or (2) generally (rather than uniquely) desirable personal characteristics such as articulateness, positive personal appearance, and good general communication skills. However, some systematic differences were detected in the extent to which particular characteristics were sought by recruiters in different colleges or by those recruiting for different types of vacancies. Findings are related to previous research, and implications for applicants, employers, and future researchers are offered

    Differential processing of plasma-ANF in cardiovascular disease

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    Benchmark solutions for the galactic heavy-ion transport equations with energy and spatial coupling

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    Nontrivial benchmark solutions are developed for the galactic heavy ion transport equations in the straightahead approximation with energy and spatial coupling. Analytical representations of the ion fluxes are obtained for a variety of sources with the assumption that the nuclear interaction parameters are energy independent. The method utilizes an analytical LaPlace transform inversion to yield a closed form representation that is computationally efficient. The flux profiles are then used to predict ion dose profiles, which are important for shield design studies

    Verifying timestamps of occultation observation systems

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    We describe an image timestamp verification system to determine the exposure timing characteristics and continuity of images made by an imaging camera and recorder, with reference to Coordinated Universal Time (UTC). The original use was to verify the timestamps of stellar occultation recording systems, but the system is applicable to lunar flashes, planetary transits, sprite recording, or any area where reliable timestamps are required. The system offers good temporal resolution (down to 2 msec, referred to UTC) and provides exposure duration and interframe dead time information. The system uses inexpensive, off-the- shelf components, requires minimal assembly and requires no high-voltage components or connections. We also describe an application to load FITS (and other format) image files, which can decode the verification image timestamp. Source code, wiring diagrams and built applications are provided to aid the construction and use of the device.Comment: 10 pages, 7 figures, accepted to Publications of the Astronomical Society of Australia (PASA

    Quality control limits for antimicrobial susceptibility tests of cefpirome

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