76 research outputs found

    PORT ELEVATOR CAPACITY AND NATIONAL AND WORLD GRAIN SHIPMENTS

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    An analysis is conducted on the port component of the United States grain export system. A transshipment model is utilized which covers both United States internal and foreign shipments of corn, soybeans, and wheat during the four quarters of a year. The model suggests that there will be quarter to quarter constraints on port capacity but that annual capacity is adequate. Through sensitivity analysis a number of key factors were found which influence the adequacy of the current port system. Port adequacy is found to depend not as much on export market location as it does on domestic transportation rates and policies.International Relations/Trade,

    Report of NSF Workshop Series on Scientific Software Security Innovation Institute

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    Many individuals attended these workshops and contributed to the writing of this report. They are named in the report itself.Over the period of 2010‐2011, a series of two workshops were held in response to NSF Dear Colleague Letter NSF 10‐050 calling for exploratory workshops to consider requirements for Scientific Software Innovation Institutes (S2I2s). The specific topic of the workshop series was the potential benefits of a security-­‐focused software institute that would serve the entire NSF research and development community. The first workshop was held on August 6th, 2010 in Arlington, VA and represented an initial exploration of the topic. The second workshop was held on October 26th, 2011 in Chicago, IL and its goals were to 1) Extend our understanding of relevant needs of MREFC and large NSF Projects, 2) refine outcome from first workshop with broader community input, and 3) vet concepts for a trusted cyberinfrastructure institute. This report summarizes the findings of these workshops.This material is based upon work supported by the National Science Foundation under grant number 1043843. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science

    Prospectus, October 26, 1973

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    STAFF PROFILES; Trustees Welcome Stugo President Kendricks To Board; Chills Highlight Haunted House; Only Two Of Seven Amendments Pass, Original Report Incorrect; Prospectus In Perspective: Impeachment Now; The Short Circuit; Cruisin\u27 \u2773; Senator Hulsizer Asks For Student Involvement; Letters From Our Readers; To the Faculty of Parkland College; Bowling Bulletin Board; Death By Hunger; TARGET Explained At Open House; Behind The Books; Scott I Deal With The Issues ; Human Development Seminar Slated; The History Of The Controversial Film - Salt Of The Earth ; S.W.A.M.P. Not A Fad; News Bulletin; Allman Bros. Come Through On Brothers and Sisters; Johnson We Take The Student Where He Is, and Build On That ; Campus Continues To Be Completed; Pre-Registration Additional Info; Mutt and Mortie; Leaders To Meet At Allerton This Saturday, Sunday; Debaters Shows Strength At Bradley Tourney; Health Center Free Clinic; Day Senators Outline Platforms; Slave Auction, Dance Today; President Releases Tapes; Marshall Wins PCFW Scholarship; A\u27s Repeat As World Champs, Dump N.Y. Mets In Seven Games; Wrist-Wrestling, Frisbie Contests To Be Held Soon; Monday\u27s Coach; Harriers Lose Flores Burnette, Will Run In Region IV Finals On Saturday, October 26; Fast Freddy\u27s Football Forecast; Fast Freddy Pays In Cash, Too; Female Winner Of Fast Freddy; Classified Ads; Champaign To Pick Up Leaves; Masters\u27 \u27Spoon River\u27 Comes To Parkland; A Column By And For Women; What The Signs Say; W. Virginia U. Hires Attorney; Who Will Listen?; Final Exam Schedule - Fall Quarter; Callboard; Sharing Group Recommends Eighthttps://spark.parkland.edu/prospectus_1973/1003/thumbnail.jp

    Prospectus, November 9, 1973

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    FORD - OUR NEXT PRESIDENT?; Faculty, Staff Evaluations Adopted As College Policy; Fellowships For Women Announced; Student Senate Vice-President Resigns Post; Debaters Take Third At IVC Meet; Vandalism Suspected In Fire; Parkland To Participate In Conference; Declaration Of Impeachment; Prospectus In Perspective; Letters From Our Readers; Student Opinion Survey; President\u27s Comment; The Short Circuit; Behind The Books; Counselors And Question Marks; Zindars Shares Her Experiences; $6 Bid Tops In Vets Dance, Slave-Auction; UFO\u27s: Citizens Vs. Air Force; The Pinkertons Are At Parkland; Allied Health Program; November Student Activities Parkland College; American Assoc. Of Univ. Women Host General Meeting Nov. 11; Peterson Addresses Phi Beta Lambda; PLATO Popular With Students, Teachers; Cycle Mishap Injures One; Road Rally; Mutt and Mortie; Evening Program Diversified Next Quarter At P/C; Geology Flight Delayed; Final Exam Schedule - Fall Quarter; Costs At School Dominate P.C.A. Senate Meeting; \u27Passion Play\u27 Not Dull; P/C Gen. Biology-Pollution, Genetics Other Relevant Topics; No Grease-Monkey Graduatess At Parkland; Campus Leaders Exchange Ideas at Allerton Meeting; Parkland Co-Hosts Veterans Conference; TB Examinations; Classified Ads; A Column By And For Women: Originality, The Cell; Monday\u27s Coach; Jim Redman, Jane Hawthorne Grab Parkland\u27s First Road Rally; Football Finals To Be Held Tuesday; Fast Freddy\u27s Football Forecast; WVLJ Plans Broadcasts Of PC Basketball; Thompson Wins Fast Freddy As Upsets Abound; Local Volunteer Suggests Grants; Lost And Found; Earle, Seger Go To N.J.C.A.A. Nationals; Parkland Cagers Start Practice For Nov. 29 Debut With Millikin; Wrestlers Open Workouts, Seven Spots Open On 10-Man Roster; Parkland College Basketball Schedule 1973-74; Parkland College Wrestling Schedule 1973-74; Bowing Bulletin Board; Callboard; Changes In Calendar, Staff Status, Registration Proposed; Cade Re-elected Board Chairmanhttps://spark.parkland.edu/prospectus_1973/1002/thumbnail.jp

    Prospectus, September 28, 1973

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    OVERWHELMING RESPONSE TO ACTIVITIES WEEK; Four File Petitions For Senator; Variety Talent Needed For October Show; David Stanley Named To Head Parkland Prospectus Staff; Reactions To New Drinking Law; Toy For Kids And War; Guest Editorial; Prospectus In Perspective: Student President\u27s Report; Boycott Non-Union Lettuce; Roving Counselors New Addition To FSM Centers; Lake: \u27Energy...Essence of Art\u27; Walker Defends Positions On Schools, Lakes; Board Approves Operating Budget; New Faculty Members; Counselors\u27 Schedule For FSM; Prospectus Plan Presented To Board Members; Want To Sing, Swing, Play?; Students Find Voice In College Government; Candidates Draft Platforms, Elections On Oct. 10-11; Black Art/Poetry; Dental Services Free To Students; Audubon Society Opens Season; Monday\u27s Coach; Hustler Is Hustled As King Wins Crown; Outreach Program To Bridge Gap; \u27A Quarter\u27s Worth\u27 Selects Editor; Mailer To Lecture At River Forest; Mike Scruggs Wins Football Contest; Road Rally & Sports Car Club; Earle Grabs Successive Cross Country Titles; Linksmen Seventh In Golf Opener; Touch Football Gets Underway, Intramurals In Full Swing; Trucker\u27s Lead Bowling League; Fast Freddy\u27s Football Forecast; Carlin Social Parody Blows Mind; Mutt and Mortie; Board Discusses Student Rep; Dear Mr. Secretary; Explicit Needs Fulfilled By Black Groups; The Short Circuit; Letters From Our Readers; Debate Competition Opens Against Western Illinois; Classified Ads; Faculty Wives Outline Programs; Program List For 1973-74; LRC Ready For Students; Rosh Hashanah Signals Start Of Jewish Holidays; Callboard; I. E. Team Plans Intercollegiate Competition; Krannert Art Center Schedule; Staff Requests News Releaseshttps://spark.parkland.edu/prospectus_1973/1005/thumbnail.jp

    2011 Report of NSF Workshop Series on Scientific Software Security Innovation Institute

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    Over the period of 2010-2011, a series of two workshops were held in response to NSF Dear Colleague Letter NSF 10-050 calling for exploratory workshops to consider requirements for Scientific Software Innovation Institutes (S2I2s). The specific topic of the workshop series was the potential benefits of a security-focused software institute that would serve the entire NSF research and development community. The first workshop was held on August 6th, 2010 in Arlington, VA and represented an initial exploration of the topic. The second workshop was held on October 26th, 2011 in Chicago, IL and its goals were to 1) Extend our understanding of relevant needs of MREFC and large NSF Projects, 2) refine outcome from first workshop with broader community input, and 3) vet concepts for a trusted cyberinfrastructure institute. Towards those goals, the participants other 2011workshop included greater representation from MREFC and large NSF projects, and, for the most part, did not overlap with the participants from the 2010 workshop. A highlight of the second workshop was, at the invitation of the organizers, a presentation by Scott Koranda of the LIGO project on the history of LIGO’s identity management activities and how those could have benefited from a security institute. A key analysis he presented is that, by his estimation, LIGO could have saved 2 senior FTE-years of effort by following suitable expert guidance had it existed. The overarching finding from the workshops is that security is a critical crosscutting issue for the NSF software infrastructure and recommended a security focused activity to address this issue broadly, for example a security software institute (S2I2) under the SI2 program. Additionally, the 2010 workshop participants agreed to 15 key additional findings, which the 2011 workshop confirmed, with some refinement as discussed in this report.NSF Grant # 1043843Ope

    Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

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    Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

    Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

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    Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN

    Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas

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    This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five sites associated with smokin
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