27,069 research outputs found

    Quality of life and building design in residential and nursing homes for older people

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    Older people living in residential and nursing care homes spend a large proportion of their time within the boundaries of the home, and may depend on the environment to compensate for their physical or cognitive frailties. Regulations and guidelines on the design of care buildings have accumulated over time with little knowledge of their impact on the quality of life of building users. The Design in Caring Environments Study (DICE) collected cross-sectional data on building design and quality of life in 38 care homes in and near Sheffield, Yorkshire. Quality of life was assessed using methods which included all residents regardless of their frailty, and staff morale was also assessed. The physical environment was measured on 11 user-related domains using a new tool, the Sheffield Care Environment Assessment Matrix (SCEAM). Significant positive associations were found between several aspects of the built environment and the residents' quality of life. There was evidence that a focus on safety and health requirements could be creating risk-averse environments which act against quality of life, particularly for the least frail residents. Staff morale was associated with attributes of a non-institutional environment for residents rather than with the facilities provided for the staff. The new tool for assessing building design has potential applications in further research and for care providers

    Achieving Consistent Doppler Measurements from SDO/HMI Vector Field Inversions

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    NASA's Solar Dynamics Observatory is delivering vector field observations of the full solar disk with unprecedented temporal and spatial resolution; however, the satellite is in a highly inclined geostationary orbit. The relative spacecraft-Sun velocity varies by ±3\pm3~km/s over a day which introduces major orbital artifacts in the Helioseismic Magnetic Imager data. We demonstrate that the orbital artifacts contaminate all spatial and temporal scales in the data. We describe a newly-developed three stage procedure for mitigating these artifacts in the Doppler data derived from the Milne-Eddington inversions in the HMI Pipeline. This procedure was applied to full disk images of AR11084 to produce consistent Dopplergrams. The data adjustments reduce the power in the orbital artifacts by 31dB. Furthermore, we analyze in detail the corrected images and show that our procedure greatly improve the temporal and spectral properties of the data without adding any new artifacts. We conclude that this new and easily implemented procedure makes a dramatic improvement in the consistency of the HMI data and in its usefulness for precision scientific studies.Comment: 58 pages, 19 figures, submitted to Ap

    Evidence of Pentaquark States from K+ N Scattering Data?

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    Motivated by the recent experimental evidence of the exotic B = S = +1 baryonic state Theta(1540), we examine the older existing data on K+ N elastic scattering through the time delay method. We find positive peaks in time delay around 1.545 and 1.6 GeV in the D03 and P01 partial waves of K+ N scattering respectively, in agreement with experiments. We also find an indication of the J=3/2 Theta* spin-orbit partner to the Theta, in the P03 partial wave at 1.6 GeV. We discuss the pros and contras of these findings in support of the interpretation of these peaks as possible exotics.Comment: 10 pages, 4 figure

    Progression and assessment in foreign languages at Key Stage 2

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    The teaching of primary languages has been increasing steadily, in response to the future entitlement for all Key Stage 2 (KS2) pupils aged 7-11 to learn a foreign language by 2010. However, there remain concerns about progression both within KS2 and through to secondary school and about how learners' progress is assessed. This paper presents findings on the issues of progression and assessment taken from case studies which formed part of a project funded by the then Department for Education and Skills (DfES), now the Department for Children, Schools and Families (DCSF). This project set out to evaluate 19 local authority (LA) Pathfinders in England that were piloting the introduction of foreign language learning at KS2 between 2003 and 2005. Findings revealed that there was inconsistency between schools, even within each LA Pathfinder, in the use of schemes of work and that assessment was generally underdeveloped in the majority of the Pathfinders. In order to set these findings in context, this paper examines the issues of progression and assessment in foreign language learning in England. Finally, it investigates the challenges English primary schools face in terms of progression and assessment in the light of the new entitlement and discusses implications for the future. Managing progression, both within KS2 and through to secondary school at KS3 (ages 11-14), is one of the key factors in determining the overall success of starting languages in primary school

    From ‘other’ to involved: User involvement in research: An emerging paradigm

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    This article has been made available through the Brunel Open Access Publishing Fund. Copyright @ 2013 The Author(s). This is an Open Access article. Non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly attributed, cited, and is not altered, transformed, or built upon in any way, is permitted. The moral rights of the named author(s) have been asserted.This article explores the issue of ‘othering’ service users and the role that involving them, particularly in social policy and social work research may play in reducing this. It takes, as its starting point, the concept of ‘social exclusion’, which has developed in Europe and the marginal role that those who have been included in this construct have played in its development and the damaging effects this may have. The article explores service user involvement in research and is itself written from a service user perspective. It pays particular attention to the ideological, practical, theoretical, ethical and methodological issues that such user involvement may raise for research. It examines problems that both research and user involvement may give rise to and also considers developments internationally to involve service users/subjects of research, highlighting some of the possible implications and gains of engaging service user knowledge in research and the need for this to be evaluated

    Tidal Evolution of Close-in Extra-Solar Planets

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    The distribution of eccentricities e of extra-solar planets with semi-major axes a > 0.2 AU is very uniform, and values for e are relatively large, averaging 0.3 and broadly distributed up to near 1. For a < 0.2 AU, eccentricities are much smaller (most e < 0.2), a characteristic widely attributed to damping by tides after the planets formed and the protoplanetary gas disk dissipated. Most previous estimates of the tidal damping considered the tides raised on the planets, but ignored the tides raised on the stars. Most also assumed specific values for the planets' poorly constrained tidal dissipation parameter Qp. Perhaps most important, in many studies, the strongly coupled evolution between e and a was ignored. We have now integrated the coupled tidal evolution equations for e and a over the estimated age of each planet, and confirmed that the distribution of initial e values of close-in planets matches that of the general population for reasonable Q values, with the best fits for stellar and planetary Q being ~10^5.5 and ~10^6.5, respectively. The accompanying evolution of a values shows most close-in planets had significantly larger a at the start of tidal migration. The earlier gas disk migration did not bring all planets to their current orbits. The current small values of a were only reached gradually due to tides over the lifetimes of the planets. These results may have important implications for planet formation models, atmospheric models of "hot Jupiters", and the success of transit surveys.Comment: accepted to Ap

    Measurement of Spin Transfer Observables in Antiproton-Proton -> Antilambda-Lambda at 1.637 GeV/c

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    Spin transfer observables for the strangeness-production reaction Antiproton-Proton -> Antilambda-Lambda have been measured by the PS185 collaboration using a transversely-polarized frozen-spin target with an antiproton beam momentum of 1.637 GeV/c at the Low Energy Antiproton Ring at CERN. This measurement investigates observables for which current models of the reaction near threshold make significantly differing predictions. Those models are in good agreement with existing measurements performed with unpolarized particles in the initial state. Theoretical attention has focused on the fact that these models produce conflicting predictions for the spin-transfer observables D_{nn} and K_{nn}, which are measurable only with polarized target or beam. Results presented here for D_{nn} and K_{nn} are found to be in disagreement with predictions from existing models. These results also underscore the importance of singlet-state production at backward angles, while current models predict complete or near-complete triplet-state dominance.Comment: 5 pages, 3 figure

    Particle growing mechanisms in Ag-ZrO2 and Au-ZrO2 granular films obtained by pulsed laser deposition

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    Thin films consisting of Ag and Au nanoparticles embedded in amorphous ZrO2 matrix were grown by pulsed laser deposition in a wide range of metal volume concentrations in the dielectric regime (0.08<x(Ag)<0.28 and 0.08<x(Au)<0.52). High resolution transmission electron microscopy (TEM) showed regular distribution of spherical Au and Ag nanoparticles having very sharp interfaces with the amorphous matrix. Mean particle size determined from X-ray diffraction agreed with direct TEM observation. The silver mean diameter increases more abruptly with metal volume content than that corresponding to gold particles prepared under the same conditions. Two mechanisms of particle growing are observed: nucleation and particle coalescence, their relative significance being different in both granular systems, which yields very different values of the percolation threshold (xc(Ag)~0.28 and xc(Au)~0.52).Comment: 6 figure

    Oxidative stress dependent microRNA-34a activation via PI3Kα reduces the expression of sirtuin-1 and sirtuin-6 in epithelial cells

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    Sirtuin-1 (SIRT1) and SIRT6, NAD(+)-dependent Class III protein deacetylases, are putative anti-aging enzymes, down-regulated in patients with chronic obstructive pulmonary disease (COPD), which is characterized by the accelerated ageing of the lung and associated with increased oxidative stress. Here, we show that oxidative stress (hydrogen peroxide) selectively elevates microRNA-34a (miR-34a) but not the related miR-34b/c, with concomitant reduction of SIRT1/-6 in bronchial epithelial cells (BEAS2B), which was also observed in peripheral lung samples from patients with COPD. Over-expression of a miR-34a mimic caused a significant reduction in both mRNA and protein of SIRT1/-6, whereas inhibition of miR-34a (antagomir) increased these sirtuins. Induction of miR-34a expression with H2O2 was phosphoinositide-3-kinase (PI3K) dependent as it was associated with PI3Kα activation as well as phosphatase and tensin homolog (PTEN) reduction. Importantly, miR-34a antagomirs increased SIRT1/-6 mRNA levels, whilst decreasing markers of cellular senescence in airway epithelial cells from COPD patients, suggesting that this process is reversible. Other sirtuin isoforms were not affected by miR-34a. Our data indicate that miR-34a is induced by oxidative stress via PI3K signaling, and orchestrates ageing responses under oxidative stress, therefore highlighting miR-34a as a new therapeutic target and biomarker in COPD and other oxidative stress-driven aging diseases
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