The Dog in the Middle Ages

Senior Project submitted to The Division of Multidisciplinary Studies of Bard College

CONSUMER PERCEPTIONS AND ATTITUDES TOWARDS BOVINE SOMATOTROPIN

This article investigates the possible negative effects of bovine somatotropin (bST) and antibiotic use in cows on fluid-milk consumption in New York State. Based on data from a consumer survey, the potential change in milk consumption due to bST and antibiotic use is estimated. In addition, the current perceptions of consumers about bST and antibiotics are measured, and the significant socioeconomic, demographic, and attitudinal characteristics of consumers that are related to their milk-consumption response to bST are identified. Depending upon consumer awareness of bST, the results indicate that milk consumption in New York State could decrease by 5.5% to 15.6% if bST is approved. The results also suggest that antibiotic use in cows could decrease milk consumption by 1.6% to 7%, depending upon consumer awareness. A major implication is that education will likely play an important role in influencing consumers' attitudes and perceptions about both bST and antibiotics.Consumer/Household Economics, Livestock Production/Industries,

Characterization of turbulent exchange processes in real urban street canyons with and without vegetation

Recent studies on turbulent exchange processes between the urban canopy layer and the atmosphere above have focused primarily on mechanical effects and less so on thermal ones, mostly by means of laboratory and numerical investigations and rarely in the real environment. More recently, these studies have been adopted to investigate city breathability, urban comfort and citizen health, with the aim to find new mitigation or adaptation solutions to air pollution and urban heat island, to enhance the citizen wellness. To investigate the small-scale processes characterizing vegetative and non-vegetative urban canopies, two field campaigns have been carried out within the city of Bologna, Italy. New mechanical and thermal time scales, and their ratios (rates), associated with inertial and thermal flow circulations, have been derived to this scope. In the non-vegetated canopy, mechanical time scales are found to describe fast exchanges at the rooftop and slow within the canopy, while thermal ones to describe fast mixing in the whole canopy. Faster processes are found in the vegetative canopy, with rapidly mixed mechanical time scales and varying thermal ones. The exchange rates are found to identify favorable mixing conditions in the 50−75% of the investigated period, but extreme disadvantageous events can totally suppress the exchanges. The exchange rates are also found to drive the pollutant removal from vegetated and non-vegetated canopies, with an efficacy which depends on the in-canyon circulation. The impacts of real trees in a real neighborhood of the city is tackled with a simplified fluid-dynamics model, where mean flow and turbulence are studied with different vegetation cofigurations, topological and morphological characteristics. Vegetation is found to increase both blocking and channeling effects on the mean flow and to modify the production/dissipation rate of turbulence, depending on the wind direction and topology. Nevertheless, buildings maintain a predominant impact on the atmospheric flows

Interconnection between Scales for Friendly and Affordable Sustainable Urban Districts Retrofitting

The EU FP7 project FASUDIR (Friendly and Affordable Sustainable Urban Districts Retrofitting) supports the mobilization of the building retrofitting market towards 2020-2050 EU-targets through an Integrated Decision Support Tool (IDST), a software based on a new methodology that will help decision makers identify the best energy retrofitting strategy to increase the sustainability of the whole district. Improving the sustainability of urban environments is a interscalar problem, addressed through a multiscalar and multidirectional approach. A comprehensive urban scale strategy considers the working scale, but the measures at building scale have to be coherent with the global objectives at district and city scale. The FASUDIR IDST and methodology interconnect and visualize information across scales, ensuring comprehensive diagnoses and proper implementation of strategies. Due to the complexity of urban sustainability, interscalarity and multiscalarity, first it has been necessary to identify the possible scales of analysis, to capture various themes and to highlight the horizontal and vertical interconnections between different components. Multiscalarity and Interscalarity affect the three phases of the sustainable retrofitting cycle: diagnosis, decision making and management. The identification of the impact of district solutions on buildings (and vice versa) and their compatibility across scales has been addressed through interconnected building and district Key Performance Iindicators (KPIs). The intervention phases at building level generate new information about specific buildings, enabling more accurate decision making at district level. The methodology articulates the structure of the new information and the feedback generated during the process. To allow information interconnection a strategic information management is key. A multiscale information model based on CityGML, a standard data model issued by the OGC (Open Geospatial Consortium), will be the baseline structure for all the district-scale information (geometric and semantic) that is necessary for decision making and management, organized into a single interoperable data model that will integrate information from different fields and at different levels of detail.European Commission's FP

Prognostic Factors of Renal Involvement in Systemic Sclerosis

Background/Aims: Renal involvement is common in systemic sclerosis (SSc), including asymptomatic reduction of glomerular filtration rate (GFR), increased renal resistance indices, scleroderma renal crisis (SRC) and ANCA-associated vasculitis. The aim was to evaluate type and evolution of renal involvement for a period of five years. Methods: 121 SSc patients (100 F, 21 M) with mean age of 54.9 ± 13.8, disease duration of 9 ± 6 years, of which 62 had a diffused form and 59 limited form were enrolled. All patients were screened annually for renal function by laboratory examination, ultrasound and color Doppler ultrasound of renal arteries. Results: Over the five-year observation period, 6 SRC (3 M, 3 F) occurred, four of which required dialysis. One patient developed ANCA-related proliferative glomerulonephritis and the other one acute tubular necrosis. The remaining 113 patients had a preserved renal function (serum creatinine 0.75 ± 0.24 mg/dl, GFR 93.8 ± 20 ml/min, 24h proteinuria 0.20 ± 0.15 g). Doppler indices of intrarenal arterial stiffness increased with progression of capillaroscopic damage and with presence of digital ulcers. A negative correlation was observed between estimated GFR and pulsatile index (p< 0,05, r=-0.198), resistive index(p< 0,01, r=0.267), S/D ratio (p< 0,01, r=-0.237). Conclusion: In SSc patients, renal function was normal for 4.1 years despite the presence of increased intrarenal arterial stiffness. SRC was observed in 4.9% of SSc patients. In SSc patients, a periodic follow-up based on clinical and laboratory evaluation, colorDoppler ultrasound and, in some cases, renal biopsy is required to evaluate renal involvement

Intrarenal arterial stiffness is increased in systemic sclerosis patients with anti-ribonucleic acid polymerase III antibodies

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Feasibility Test of the MedaCube

Poor adherence is a significant barrier to achieve better patient outcomes. Rates of non-adherence approach 40% resulting in 10% of all emergency department visits and 23% of admissions into skilled nursing facilities. Many factors contribute to medication non-adherence including psychological and memory disorders, aging and pill burden. The MedaCube is a medication management system intended to help solve unintentional medication non-adherence. The device is designed to dispense scheduled and as-needed oral medications. The MedaCube provides audio and visual prompts alerting subjects to administer their medications. Caregivers receive notification of missed doses, late doses and refill requests. The null hypothesis is that use of the MedaCube results in no difference in medication adherence when compared with six month prior adherence in individual subjects

Evaluation of estimated glomerular filtration rate and clinical variables in systemic sclerosis patients

Objectives: The most important renal complication of systemic sclerosis (SSc) is scleroderma renal crisis (SRC). Many patients demonstrate less severe renal complications, most likely associated with reduced renal blood flow and a consequent reduction in glomerular filtration rate (GFR). The mechanism of this slowly progressive form of chronic renal disease is unclear. The aim of this study was to evaluate GFR by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and the 7-variable Modification of Diet and Renal Disease (MDRD) equations in SSc patients and to correlate estimated GFR (eGFR) with clinical variables of the disease. Methods: 105 unselected and consecutive patients with SSc were enrolled. Serum creatinine was measured in all patients and GFR was estimated by 7-variable MDRD and CKD-EPI equations. Nailfold videocapillaroscopy was performed in all patients. Results: The mean value of eGFR evaluated by both 7-variable MDRD and CKD-EPI was significantly different (p < 0.0001) in the three capillaroscopic groups and correlated negatively with the severity of capillaroscopic damage (early: 95 ± 16 mL/min and 101 ± 12 mL/min, active: 86 ± 25 mL/min and 95 ± 17 mL/min, late: 76 ± 21 mL/min and 82 ± 21 mL/min). The mean value of eGFR evaluated by 7-variable MDRD (97 ± 23 mL/min vs. 74 ± 15 mL/min, p < 0.0001) and CKD-EPI (0.83 ± 0.20 mL/min vs. 0.68 ± 0.10 mL/min, p < 0.0001) was significantly higher in SSc patients without history of digital ulcers than in those with. Conclusion: We can conclude that in SSc patients without renal involvement, eGFR decreases with the progression of digital vascular damag