भारत में समुद्री अक्वापोनिक्स प्रणालियों की जीवन क्षमता

Viability of marine aquaponics systems in Indi

A Study on Strengthening the Operational Efficiency of Dairy Supply Chain in Tamilnadu, India

AbstractThe main objective of this paper is to study the issues in improving the operational efficiency of the dairy supply chain in Tamil Nadu, India. Dairy Farming is a major occupation of the people of Tamil Nadu, India and it contributes a significant amount to the growth of our country. In this paper, Tamil Nadu dairy development department's objectives and its three-tier structure were studied. Through SWOT analysis its strengths, weaknesses, opportunities and threats were analyzed. In our study Tamil Nadu Cooperative Milk Producers Federation is compared with Gujarat Cooperative Milk Producers Federation (AMUL). The major issues influencing the dairy farming are studied through literature survey, field study and researchers experience. They are presented in this paper. There were three major important field studies conducted at various time periods. The data has been collected through a questionnaire method and these interactions were recorded by a video camera. Based on the research work carried out on dairy supply chain in Tamil Nadu, India, some key recommendations are made for the attention of policy makers to strengthen the operational efficiency. There are five areas of focus. They are, creation of special dairy zone, implementing dynamic milk procurement method, strengthening cooperative societies, creation of feed bank and increasing fodder productivity, integrated animal health plan and information technology

Comparative in vivo study of pure drug and fast dissolving tablets of Simvastatin

The objective of this study was to investigate differences in the pharmacokinetic patterns between pure drug and an optimized  formulation of fast dissolving tablets  of Simvastatin. The formulations were administered to 2 groups of white New Zealand rabbits (n=6) following cross over design pattern and the plasma levels were measured using LC-MS/MS method. Pharmacokinetic parameters were determined for each formulation. The comparison of the plasma time curves of the dosage forms showed that each dosage form caused significant differences in the drug plasma levels.  The highest mean Cmax value was observed for optimized fast dissolving tablets (68.33 ± 0.42ng/ml) compared to  pure drug (27.72 ± 0.31ng/ml). The mean time taken to peak plasma concentration for (Tmax) following administration of pure drug  was  11.53 ± 0.011hours, while it was 6.09 ± 0.072 hour following administration of selected optimized fast dissolving tablets.The elimination rate constant (Kel) for pure drug and optimized fast dissolving tablets were found to be 0.58 ± 0.012h-1and 0.53 ± 0.014 h-1 respectively.  The absorption rate constant (Ka) for pure drug and optimized fast dissolving tablets were found to be 1.68 ± 0.01h-1and 5.53 ± 0.02h-1 respectively. The AUC0-αvalues observed with optimized fast dissolving tablets686.1.±2.07 nghr/ml in compared to pure drug values 191 ± 1.43 nghr/ml. Thus, the results of pharmacokinetic studies indicated rapid and higher oral absorption of Simvastatin when administered as its fast dissolving tablets. Both Ka and AUC were markedly increased by fast dissolving tablets. Keywords: LC-MS/MS, Simvastatin, fast dissolving, In-vivo studies, pharmacokinetic parameters

A randomized controlled study of nebulized 3% saline versus 0.9% saline with adrenaline in the treatment of acute bronchiolitis

Objective: The objective was to determine whether nebulized hypertonic (3%) saline with adrenaline is more effective than nebulized0.9% saline with adrenaline in the treatment of acute bronchiolitis. Materials and Methods: In this randomized, double-blind, controlledstudy 100 patients were randomly allocated into two groups (50 patients in each group). In Group A (normal saline group), 4 ml ofnormal saline (0.9%) and 1 ml of 1:1,000 adrenaline was given as nebulization with oxygen flow of 6-8 L/min. In Group B (hypertonicsaline group), 4 ml of hypertonic saline (3%) and 1 ml of 1:1,000 adrenaline was given as nebulization with oxygen flow of 6-8 L/min.The nebulization was given at an interval of 4 h, 6 times daily till the patient was ready for discharge. Results: The percentageimprovement in clinical severity scores after inhalation therapy was not significant in Group A on 1st-3rd day after admission (3.4%,2.1%, and 4%, respectively). In Group B, significant improvement was observed on these days (7.4%, 8.7%, and 9.9%, respectively,p<0.001). Furthermore, the improvement in clinical severity scores differed significantly on each of these days between the two groups.Using 3% saline decreased the hospitalization stay by 25%, from 3.4±1.7 days in Group A to 2.5±1.4 days in Group B (p<0.05).Conclusion: In the treatment of acute bronchiolitis, 3% saline nebulization with adrenaline decreases the length of hospitalization andsymptoms as compared to 0.9% saline nebulization

Low saline aquaponics system with Silver Pompano as a candidate species

Aquaponics is a sustainable food production system that integrates hydroponics and aquaculture practices in order to attain optimum utilization of nutrients by re-cycling. Aquaponics facilitates the symbiotic production of vegetables and fishes with minimum inputs, organic farming like management and higher control on production. Aquaponics system is extremely water efficient, does not require soil and does not use fertilizers or chemical pesticides. Silver pompano Trachinotus blochii is a preferred candidate species for mariculture due to the availability of hatchery produced seed, adaptability to commercial pellet feeds, good market demand and excellent meat quality. The species has proven good for farming in both marine as well as low saline water bodies. Adopting the principles of nutrient utilization in aquaponics and the ability of silver pompano to grow in low saline conditions, a prototype of a low saline aquaponics system integrating one month reared fingerlings of silver pompano T. blochii, with a common, leafy vegetable Amaranthus by employing a 0.25 hp submersible pump for recirculation was developed

Orange Chromide (Etroplus maculatus): A promising indigenous fish for marine aquariums

Etroplus maculatus, commonly known as Orange chromide is a euryhaline fish endemic to brackishwater streams, lagoons, estuaries and the lower reaches of rivers in peninsular India and Sri Lanka. In India, it occurs in Maharashtra, Goa, Karnataka, Kerala and Tamil Nadu. The Orange chromide at present is mainly utilized as freshwater and brackishwater ornamental fish as it is reported to survive in water close to 21‰ salinity after gradual acclimatization. The present study was conducted to determine the salinity tolerance of E. maculatus to know the scope of this species to be selected as a marine ornamental fish

Seasonal availability of commercially important fish seeds in estuaries of Kozhikode, Kerala

Availability of fish seed for culture is one of the major constraints in expanding mariculture in India. Capture-based aquaculture (CBA) is the practice of rearing wild collected fish seeds from early life stages to adults in captivity to marketable size, employing different aquaculture techniques. It is estimated that about 20 percent of world aquaculture production comes from CBA. The availability of cultivable fish seeds in estuaries of Kozhikode district in Kerala has been surveyed and the potential wild seed grounds identified were in Kadalundi, Korapuzha and Karuvanthuruthi estuaries. The quantitative availability of fish seeds in these localities during different seasons was evaluated

Acanthopagrus berda - a potential species for mariculture in India

Sea breams belonging to the sparidae familyare excellent food fishes and important candidate species for aquaculture. Globally, the river bream, Acanthopagrus berda is highly valued in commercial fisheries and aquaculture due to their excellent meat quality, market demand, easy adaptability to captivity and ability to tolerate wide variations in both salinity and temperature. A. berda is distributed in the estuarine and shallow coastal waters of Kerala, Tamil Nadu, Andhra Pradesh, Maharashtra and Gujarat coasts (Fig.1). Locally known as “Karuthaeri” along Kerala coast they are fished by artisanal fishers using cast nets and hook & line and fetch ` 400-500 per kg in the domestic markets. At present, India is looking for native food fishes for mariculture development and A. berda is considered as a priority species due to their high market demand

Loss of the mechanotransducer zyxin promotes a synthetic phenotype of vascular smooth muscle cells.

BACKGROUND: Exposure of vascular smooth muscle cells (VSMCs) to excessive cyclic stretch such as in hypertension causes a shift in their phenotype. The focal adhesion protein zyxin can transduce such biomechanical stimuli to the nucleus of both endothelial cells and VSMCs, albeit with different thresholds and kinetics. However, there is no distinct vascular phenotype in young zyxin-deficient mice, possibly due to functional redundancy among other gene products belonging to the zyxin family. Analyzing zyxin function in VSMCs at the cellular level might thus offer a better mechanistic insight. We aimed to characterize zyxin-dependent changes in gene expression in VSMCs exposed to biomechanical stretch and define the functional role of zyxin in controlling the resultant VSMC phenotype. METHODS AND RESULTS: DNA microarray analysis was used to identify genes and pathways that were zyxin regulated in static and stretched human umbilical artery-derived and mouse aortic VSMCs. Zyxin-null VSMCs showed a remarkable shift to a growth-promoting, less apoptotic, promigratory and poorly contractile phenotype with ≈90% of the stretch-responsive genes being zyxin dependent. Interestingly, zyxin-null cells already seemed primed for such a synthetic phenotype, with mechanical stretch further accentuating it. This could be accounted for by higher RhoA activity and myocardin-related transcription factor-A mainly localized to the nucleus of zyxin-null VSMCs, and a condensed and localized accumulation of F-actin upon stretch. CONCLUSIONS: At the cellular level, zyxin is a key regulator of stretch-induced gene expression. Loss of zyxin drives VSMCs toward a synthetic phenotype, a process further consolidated by exaggerated stretch

Acanthopagrus berda (Forsskål, 1775)

Acanthopagrus berda has a fairly deep, compressed body with depth about twice in standard length. Head is about 3 or 4 times in standard length with straight upper profile (sometimes with a bulge above eye) and pointed snout. Both jaws contain 4-6 large, compressed teeth in front, followed by 3-5 rows of molar-like teeth; upper lateral teeth of outer row conical and blunt. There are about 9-11 gill rakers on the lower limb of first arch. The species has a single dorsal fin with 11 (rarely 12) spines and 10-13 soft rays. The spines of dorsal fin appear alternately broad and narrow on either side with 4th to 6th spines longest. Anal fin contain 3 spines and 8 or 9 soft rays