154 research outputs found

    Impact of Buccal Corridors on Smile Esthetics

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    Aim:The purpose of the present study was to investigate the influence of buccal corridors on smile esthetics.Subjects and Methods:For this purpose, 10 individuals with following criteria were included to this study; to have an esthetic smile arc, no excessive gingival exposure, ages between 18 and 30 years and equal distribution of the sexes. These criteria and only the perioral photographs were used to limit the scope of the variables and to decrease the dilution of the results. A photo editing software was used to produce 5 varying sizes of buccal corridors and the pictures were classified as Narrow smile, Medium-narrow smile, Medium smile, Medium-broad smile and Broad smile. Altered five smile images of the individuals were showed to the panels consisted of orthodontists, prosthodontists, general dentists, lay people and drawing artists each numbered 10 juries. They were asked to rate that five images from 1 to 5. ANOVA and Tukey tests were used to make a statistical analysis.Results:All of the panels evaluated the smile images in the same manner. The broader the smile it is the more attractive. The most attractive smile was the broad smile and the least attractive was the narrow smile. All panel groups evaluated the smile images in the same manner and there were not statistically significant differences between the groups. Conclusion:These results indicate that; to gain an esthetic smile after orthodontic treatment, clinician must avoid causing broad buccal corridors

    Outcomes of high-risk breast lesions diagnosed using image-guided core needle biopsy: results from a multicenter retrospective study

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    PURPOSEThe clinical management of high-risk lesions using image-guided biopsy is challenging. This study aimed to evaluate the rates at which such lesions were upgraded to malignancy and identify possible predictive factors for upgrading high-risk lesions.METHODSThis retrospective multicenter analysis included 1.343 patients diagnosed with high-risk lesions using an image-guided core needle or vacuum-assisted biopsy (VAB). Only patients managed using an excisional biopsy or with at least one year of documented radiological follow-up were included. For each, the Breast Imaging Reporting and Data System (BI-RADS) category, number of samples, needle thickness, and lesion size were correlated with malignancy upgrade rates in different histologic subtypes. Pearson’s chi-squared test, the Fisher–Freeman–Halton test, and Fisher’s exact test were used for the statistical analyses.RESULTSThe overall upgrade rate was 20.6%, with the highest rates in the subtypes of intraductal papilloma (IP) with atypia (44.7%; 55/123), followed by atypical ductal hyperplasia (ADH) (38.4%; 144/375), lobular neoplasia (LN) (12.7%; 7/55), papilloma without atypia (9.4%; 58/611), flat epithelial atypia (FEA) (8.7%; 10/114), and radial scars (RSs) (4.6%; 3/65). There was a significant relationship between the upgrade rate and BI-RADS category, number of samples, and lesion size Lesion size was the most predictive factor for an upgrade in all subtypes.CONCLUSIONADH and atypical IP showed considerable upgrade rates to malignancy, requiring surgical excision. The LN, IP without atypia, pure FEA, and RS subtypes showed lower malignancy rates when the BI-RADS category was lower and in smaller lesions that had been adequately sampled using VAB. After being discussed in a multidisciplinary meeting, these cases could be managed with follow-up instead of excision

    Güncel Genetik Tabanlı Tarama Testleri

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    İnfertilite ve Genetik Yönü

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    Genom Teknolojilerinin Klinikte Kullanımı

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    Erişkin Yaşta Görülen Genetik Hastalıklara Yaklaşım

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