53 research outputs found
Hemşirelik Bölümü Öğrencilerinin Mesleğe Yönelme Faktörleri, Mesleki İmaj ve Beklentilerine İlişkin Görüşlerinin Belirlenmesi
Amaç: Bu çalışma, Bingöl Üniversitesi Sağlık Bilimleri Fakültesi Hemşirelik Bölümü’nde öğrenim gören öğrencilerin mesleğe yönelme faktörleri, mesleki imaj ve beklentilerine ilişkin görüşlerini saptamak amacıyla tanımlayıcı olarak yapılmıştır.Gereç ve Yöntem: Araştırmanın evrenini, 2018-2019 Akademik yılında Bingöl Üniversitesi Sağlık Bilimleri Fakültesi Hemşirelik Bölümü’nde öğrenimlerini sürdüren 286 öğrenci oluştururken, örneklemini ise araştırmanın uygulanmasına destek veren ve katılmaya gönüllü olan 251 öğrenci oluşturmuştur. Araştırma verileri, 15 Şubat – 15 Mart 2019 tarihleri arasında toplanmıştır. Araştırma verilerinin toplanmasında, “Anket Formu” ve “Hemşirelik İmajı Ölçeği HİÖ ” kullanılmıştır.Bulgular: Çalışmaya 160 kadın, 91 erkek olmak üzere 251 hemşirelik öğrencisi katılmıştır. Öğrencilerin genellikle yaşadığı yer il merkezi %65,3 , baba eğitim durumları ortaöğretim %30,7 ve anne eğitim durumları okuryazar değil %49 şeklindedir. Öğrencilerin %28,3’ü hemşirelik bölümünden memnun olduklarını ifade etmiştir. Öğrencilerin %83,7’si üniversite öncesi mesleği tanıdığını, %58,2’si ise tekrar hemşireliği seçebileceğini ifade etmiştir. Öğrencilerin Hemşirelik İmajı Ölçeği genel görünüm alt boyutu ortalamasının 10,96±2,05 olduğu, iletişim alt boyutu ortalamasının 9,22±2,80, mesleki ve eğitsel nitelikler alt boyutu ortalamasının 20,06±3,73 ve ölçek toplam puan ortalamasının ise 40,25±6,33 olduğu saptanmıştır. Hemşirelik İmaj Ölçeği alt boyut ve toplamından alınabilecek en yüksek ve en düşük puanlara göre; çalışmaya katılan bireylerdeki hemşirelik imajının orta düzeyde olumlu olduğu söylenebilir.Sonuç: Öğrencilerin büyük bir kısmının üniversite öncesi mesleği tanıdığı, hemşirelik imaj ölçeğinden aldıkları puan ortalamalarının yüksek olduğu 40,25±6,33 ve bu öğrencilerin hemşirelik mesleğine karşı olumlu bakış açısı sergiledikleri görülmüştür. Mesleği tanımanın ve olumlu bakış açısının hemşirelik imajını etkilediği ve ölçek puan ortalamasını yükselttiği görülmüştür. Bu sonuçlar doğrultusunda, öğrencilere üniversiteye başlamadan önceki eğitim hayatlarında meslek tanıtımlarının ve eğitimlerinin verilmesi, hemşirelik mesleğinin rol ve sorumluluklarının anlatılması önerilmektedi
The E6 Oncoprotein from HPV16 Enhances the Canonical Wnt/?-Catenin Pathway in Skin Epidermis In Vivo
The contribution of the Wnt signaling pathway to human papilloma virus (HPV)-induced carcinogenesis is poorly understood. In high-grade dysplastic lesions that are caused by high-risk HPVs (HR-HPV), ?-catenin is often located in the cell nucleus, which suggests that Wnt pathway may be involved in the development of HPV-related carcinomas. Most of the oncogenic potential of HR-HPVs resides on the PDZ-binding domain of E6 protein. We hypothesized that the PDZ-binding domain of the HPV16-E6 oncoprotein induces the nuclear accumulation of ?-catenin due to its capacity to degrade PDZ-containing cellular targets. To test this hypothesis, we evaluated the staining pattern of ?-catenin in the skin epidermis of transgenic mice expressing the full-length E6 oncoprotein (K14E6 mice) and measured LacZ gene expression in K14E6 mice that were crossed with a strain expressing LacZ that was knocked into the Axin2 locus (Axin2+/LacZ mice). Here, we show that the E6 oncoprotein enhances the nuclear accumulation of ?-catenin, the accumulation of cellular ?-catenin–responsive genes, and the expression of LacZ. None of these effects were observed when a truncated E6 oncoprotein that lacks the PDZ-binding domain was expressed alone (K14E6?PDZ mice) or in combination with Axin2+/LacZ. Conversely, cotransfection with either E6 or E6?PDZ similarly enhanced canonical Wnt signaling in short-term in vitro assays that used a luciferase Wnt/?-catenin/TCF-dependent promoter. We propose that the activation of canonical Wnt signaling could be induced by the HPV16-E6 oncoprotein; however, the participation of the E6 PDZ-binding domain seems to be important in in vivo models only. Mol Cancer Res; 10(2); 250–8. ©2011 AACR
Ion flotation and its applications on concentration, recovery, and removal of metal ions from solutions
Many industries, especially mining and metallurgy, deal with solutions containing ions. In some cases, these metal ions need to be concentrated and recovered from solutions and sometimes removed from wastewater. The ion flotation method has been applied for wastewater and water treatment, recovery of precious and platinum group metals, preconcentrating of rare earth elements, selective separation of multicomponent ions from dilute solutions, and analytical chemistry. It has been employed to separate heavy metals from a liquid phase using bubble attachment, originated in mineral processing. In these cases, ion flotation has an important place among other methods because it is a cheap and practical method. In this study, many ion flotation studies, especially applied at laboratory scale, were reviewed. This method gives very successful and promising results in removing heavy metals with toxic effects from wastewater and selective separation of metal ions from very low concentrated solutions. Ion flotation may take place in industrial scale operations with the new developments in flotation machines and collectors with better selectivity, high efficiency, lower cost, and environmental friendliness
Heavy metals removal from wastewaters by using coal washery wastes
Bu çalışmada ağır metal içeren endüstriyel atık su sorununa kömür yıkama tesislerinden çıkan ince boyutlu
kömür atıkları kullanılarak çözüm bulunmaya çalışılmıştır. Kömür yıkama atıkları içeriğindeki killi ve karbonlu
yapıdan dolayı adsorptif özellikleri bulunmaktadır. Atık suların içerisinde bulunan Pb, Zn, Cu ve Cd metallerinin
kömür yıkama atıklarına adsorpsiyonu, pH, temas süresi ve başlangıç konsantrasyon parametreleri ile
araştırılmıştır. Ayrıca metallerin hangi mekanizması ile giderildiğinin belirlenmesi amacıyla adsorpsiyon
deneylerine paralel çöktürme deneyleri yapılmıştır. Adsorpsiyon izotermlerinden Langmuir, Freundlich, Temkin
ve Dubinin-Radushkevich modelleri uygulanmış, bunlardan Langmuir ve Freundlich iyi sonuç verdiği
bulunmuştur. Adsorpsiyonun fiziksel olduğu ve hesaplanan Gibss serbest enerjisine göre kendiliğinden geliştiği
bulunmuştur. Bu çalışma ile kömür hazırlama tesislerinden üretilen yıkama atıklarının atık sulardan ağır metal
uzaklaştırılmasında kullanılabilecek etkili bir adsorbent olduğu belirlenmiştir.In this study, the heavy metal containing waste waters problem is solved with fine coal wastes produced from
coal washing plants. Coal washery wastes have adsorptive properties due to their clayey and carbonaceous
structure. The adsorption of Pb, Zn, Cu and Cd metals in waste water onto coal washery waste is investigated by
pH, contact time and initial concentration parameters. Besides, precipitation tests were carried out to determine
the metal removal mechanism is either precipitation or adsorption depending on pH. Langmuir, Freundlich,
Temkin and Dubinin-Radushkevich models have been applied as the adsorption isotherms, Langmuir and
Freundlich have been found to give the best correlations. It is found that adsorption mechanism is physisorption
and the Gibbs energy reaction is spontaneous. As a result of this study, the tailings of the coal preparation plants
could be employed as an efficient adsorbent for removal of metal ions from wastewater
Calcium ferrite nanoparticle production from mining wastes: marble dust and pyrite ash
Calcium ferrite nanoparticles were prepared by microwave-sonication assisted hydrothermal route obtained from mining wastes, marble dust and pyrite ash. The magnetism strength,
XRD, and FT-IR were performed. Different thermal modifications as microwave and autoclave following sintering applications were investigated. Scanning Electron Microscope images show that microwave treated calcium ferrite nanoparticles have formed as cubic shape while others have irregular-noncrystallized shapes. The arsenic removal was searched by calcium ferrite nanoparticules, found that microwave treated samples have higher capacity
Physicochemical Characterization of Natural Wollastonite and Calcite
Wollastonite and calcite minerals are significant raw materials and are extensively used due to their unique properties. Wollastonite is used in plastics, paint, ceramics, paper, resins, and in construction as a substitution for asbestos due to its chemical stability, thermal resistivity, needle-like shape, and brightness. Calcite is one of the most used raw materials because of its low hardness, high alkalinity, sorptive properties, white and bright color. Wollastonite and calcite are two minerals found together in nature. The most common method used for separating these two minerals is flotation. In this study, the surface properties of pure mineral samples were investigated. The pH profiles of both minerals were obtained by measuring the surface charge of particles followed by the measurement of the zeta potential in different collector concentrations. The wettability of minerals was examined by measuring their contact angles
Comparison of anionic, cationic and amphoteric collectors used in pyrite flotation
In this study, flotation tests were conducted with purified pyrite and ore samples. The collectors employed were anionic and cationic type such as potassium ethlyl-amyl xanthate, Tomamine M73 and Resanol Bal. According to the flotation tests, it was found that pyrite floated at low pH and depressed at high pH values with xanthates. On the other hand, in the case of cationic collectors which are Tomamine M73 (alkyl ether amine, an amphoteric surfactant) and Resanol Bal (N-3-tridecyloxy propyl 1-3 diamine, branched acetate) pyrite floated at high pH values. It was shown that amine type collectors could be efficient to selectively float pyrite from chalcopyrite at alkali pH ranges in the case of ore samples
Mandibular Actinomyces Infection Mimicking a Malignancy: Case Report
Actinomycosis is a rare, chronic, suppurative and granulomatous disease caused by Actinomyces israelii, which is a filamentous, anaerobic, gram-positive, saprophytic organism in the oral cavity. Diagnosis of actinomycosis depends on positive culture or identification of Actinomyces colonies and sulfur granules in histological specimens. In our case, a mass had been growing in the mandible for eight months. The mass appeared to be malignant, both clinically and radiologically. A histopathological examination of the mandible revealed actinomycosis. It should be noted that actinomycosis can mimic a malignancy, and for differential diagnosis, bone biopsy or fine-needle aspiration should be performed pre-operatively
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