Assessment of undergraduates’ preferences and opinions on teaching of Pharmacology

Background: The preference and opinion of undergraduate students on teaching of pharmacology was assessed using structured-based questionnaires. The objective was to determine the best way to teach pharmacology and the areas the students prefer most.Methods: The questionnaires were administered to students during academic sessions in any of their pharmacology lectures by the help of technical assistants. It was also ensured that the identity of the students was not made known except for the gender. A total of 8 questions with options ranging from 2-4 were used. Each respondent was to select only one option as the most preferred. A total of 405 students participated during the study period and it was ensured that no student participated more than once. The students recruited were 4th and 5th year medical and pharmacy students of the University of Jos, Jos, Nigeria for the 2014/2015 and 2015/2016 academic sessions.Results: The results showed that the students have high preference for latest technology teaching aids such as power point presentation and use of software for lecture notes.Conclusions: Knowledge of pharmacodynamics, clinical pharmacology and laboratory experiment were preferred and significant differences exist between observed and expected results and also between males and females in preferences among some of the options. Students need to be informed at the beginning of their lectures that pharmacology is a subject that must be regarded as a whole with no areas of preference

Quality Assessment of Borehole Water in-Terms of Selected Physicochemical Parameters in Maiduguri Urban Areas, Borno State, Nigeria

In Nigeria, over 120 million peoples use boreholes as their main source of drinking water and in-view of the increasing volume of solid waste materials in Maiduguri, it has become exigencies to evaluate the quality of borehole waters in the city. The objective of this paper is therefore to evaluate some physicochemical characteristic of borehole water samples in Maiduguri urban areas Borno State, Nigeria using standard methods. Result obtained revealed that the pH of all the water samples was within the range of 6.5 to 8.5 as recommended limit by World Health Organization (WHO). Except for the pH of borehole water at Bulumkutu ward which is acidic (6.2). The pHs of all the water from the three wards were alkaline. The total dissolved solid and the electrical conductivity of water samples from the three wards fall within the limit of WHO, except water samples from Ngarannam (1100 mg/l) and (2220 uS/cm). The concentration of major ions (Na, Mg and K) fall far below the WHO recommended limit and thus the water can said to be excellent in terms of these elements. Except for Cl ion (262 mg/g) at borehole water in Gwange ward fall above the permissible limit by WHO. The study recommends performing regular testing of different water sources within the study area to ensure that commensurate attention given is maintaining a healthy population

Social Media in Relation to Cooperate Social Responsibility in Fast Food Industry

This paper focuses on analyzing the role of social media (Facebook, Twitter, Google+,Youtube) with regards to corporate social responsibility (CSR), specifically in the fast food industry. The objectives are to identify the use of social media platforms by fast food restaurants, identify if social media integrate corporate social responsibility in their business thereby limiting marketing of unhealthy meals on their websites, and lastly, to find out if marketing of fast food products on social platforms affect users, especially the young people between the age of 15 to 25. The study analyzed and monitored 70 fast food restaurants and their social media activities. 63 0ut of 70 were found to have at least three social media platforms where they promote their products to end users and none of the restaurants have any restriction in marketing any kind of product using social media. Results from questionnaire survey also found that many social media users get adverts from fast food restaurants with 13.85% being affected to buy the food most times and 47.69% sometimes. 81.54% of the participants also agreed that social media can do a great job in limiting the free marketing of unhealthy products by fast food restaurants. Keywords: Social Media, Corporate Social Responsibility (CSR), Stakeholders, fast food

PREVENTIVE AND CURATIVE HEALTH SERVICES IN SECONDARY SCHOOLS IN BORNO STATE, NIGERIA: IMPLICATIONS FOR COUNSELLING

The study which was a survey, investigated the preventive and curative health services in secondary schools in Borno State. Target population of the study comprised of 6,786 senior secondary school students. However, 7,500 staff and students constituted the sample for the study. Researchers’ self-authored instrument tagged “School Health Services Questionnaire” (SHSQ) was used in collecting data for the study. Data collected was analyzed using descriptive and inferential statistics. Three research questions and two null-hypotheses piloted the study. Descriptive statistics of frequency counts and percentages were used in answering the research questions while t-test was used in testing the null-hypotheses at 0.05 alpha level. Results of the study revealed that nutritional, medical, immunization and preventive health services are the top most preventive and curative health services rendered in secondary schools in Borno State, while health evaluation and health counselling constituted the least health services rendered. The study also revealed significant differences between school location and health services rendered in secondary schools and that significant differences also exist between school type and health services rendered in secondary schools in Borno State, Nigeria. The implications of these findings to counselling were discussed.  Article visualizations

Domestic groundwater abstraction in Lagos, Nigeria: a disjuncture in the Science-Policy-Practice Interface?

The rapid development of groundwater systems as part of urban water supplies around the globe is raising critical questions regarding the sustainable management of this essential resource. Yet, in many major cities, the absence of an effective policy regime means that the practice of groundwater exploitation is driven by the actions of domestic households and drilling contractors. Understanding what shapes the decisions and practices of these actors, their understandings of the groundwater resource and the extent to which scientific knowledge shapes this understanding, is an area of critical importance that is currently under-researched. Using a mixed-methods methodology, the paper explores domestic practices of groundwater abstraction in Lagos, Nigeria. It finds that there is a disjuncture between the households who are actively shaping exploitation of the groundwater resource on a day-to-day basis and science and state actors. This disjuncture results in household decisions that are influenced by commonly held, but potentially outdated, perceptions of the groundwater resource rather than scientific evidence or policy instruments. The unseen nature of groundwater resources effectively renders the scale of changing groundwater conditions invisible to households and the state, adding to the challenge of influencing practice. Addressing this disjuncture requires not just more scientific knowledge, but also the active construction of interfaces with, and between, non-state actors through which knowledge can be confronted, discussed and shared

Resilience in groundwater supply systems: integrating resource based approaches with agency, behaviour and choice

Access to safe and reliable water supplies is a key goal for households and governments across most of Africa. Groundwater reserves can play a critical role in achieving this, yet risks of contamination and over-abstraction threaten to undermine the resilience of this supply. A rapidly rising trend for privately-developed wells and boreholes raises additional concerns about the vulnerability of water supplies to natural or man-made environmental shocks. The potential scale of the situation is particularly marked in Nigeria where the use of boreholes has increased exponentially since 1999 (from 10% of the population to 38% in 2015), with most other forms of water supply, notably piped tap water, falling. Developing effective groundwater management approaches that build the resilience of communities is challenging, not least given the range of different actors involved, their competing interests and demands, and variations in the hydrogeological environment. Insights from resilience studies in social science emphasise how the resilience of ecological resources to shocks and change is critically linked to the adaptive capacity of social systems and their agents. Choices made now have long-lasting effects, yet these choices are little understood. Understanding the choices made by consumers, drillers and policy actors requires a strong interdisciplinary dimension and argues for new perspectives as to how the resilience of communities and societies might be built. The project brings together a unique interdisciplinary collaboration between academics from the UK and Nigeria working in the fields of economic geography, psychology, hydrogeology and journalism studies

Glubodies: randomized libraries of glutathione transferase enzymes

AbstractBackground: The immunoglobulin framework has been mutagenized to engineer recombinant libraries of proteins as potential diagnostics and novel catalysts, although the often shallow binding cleft may limit the utility of this framework for binding diverse small organic molecules. By contrast, the glutathione S-transferase (GST) family of enzymes contains a deep binding cleft, which has evolved to accommodate a broad range of hydrophobic xenobiotics. We set out to determine whether GST molecules with novel ligand-binding characteristics could be produced by random mutagenesis of segments of the binding cleft.Results: We have identified two ligand-recognition segments (LRSs) in human GST P1, which are near the active site in the folded protein, but have characteristics indicating that the integrity of their sequence is not essential for the overall structure or activity of the protein. Libraries of GST P1-derived proteins were produced by substituting randomized sequences for an LRS or inserting random sequences into an LRS. The recombinant proteins in the libraries, collectively designated as ‘glubodies,’ generally retain enzymatic activity but differ markedly both from each other and from the parent enzyme in sensitivity to inhibition by diverse small organic compounds. In some instances, a glubody is inhibited by completely novel structures.Conclusions: We have shown that a non-antibody framework can be used to create large libraries of proteins with a wide range of binding specificities for small organic molecules. The glubodies provide a rich source of data for correlating the structural and functional features of proteins relevant to ligand binding. The criteria applied for identifying an LRS in GST P1 are generally applicable to other protein frameworks

Risks and resilience of private boreholes in Lagos, Nigeria

Water security is one of the most pressing risks facing the world. In urban areas, rapidly growing population coupled with rising incomes, falling costs, and often an absent or unreliable public water supply, mean that increasing numbers of households are choosing to install private boreholes to meet their domestic water needs. This trend is particularly prevalent in emerging global mega-cities such as Lagos, Nigeria. This multidisciplinary study begins to address the question: Does the proliferation of private boreholes strengthen or weaken the resilience of Lagos and its residents to future environmental shocks

Farmer participatory varietal selection in pearl millet: Experience across some states of Northern Nigeria

Farmers participation in the process of on-farm research does not only enrich the speed up of information gathering, but also result in large scale adoption of the product of research. A small farmer deals with a variable environment and has multiple production objectives that will affect his or her choice of crops and selection of genotypes. In areas where farmers are unfamiliar with available improved varieties, there is need of conducting effective variety evaluations with farmers. The usefulness of the participatory approach for identifying cultivars for harsh environments, which are difficult to replicate in research stations, has been recognized by the crop breeders. Participatory plant breeding/selection has shown success in identifying more number of preferred varieties by farmers in shorter time (than the conventional system), in accelerating their dissemination and increasing cultivar diversity. This paper describes how plant breeders and farmers worked together to test and selected farmers preferred pearl millet varieties; PE05684 and PE05532 from a diverse pearl millet accessions in a participatory varietal selection program conducted across some states of Northern Nigeria

Understanding risks and resilience of private boreholes in Lagos, Nigeria

Water security is one of the most pressing risks facing the world. In urban areas, rapidly growing population coupled with rising incomes, falling costs, and often an absent or unreliable public water supply, mean that increasing numbers of households are choosing to install private boreholes to meet their domestic water needs. This trend is particularly prevalent in emerging global mega-cities such as Lagos, Nigeria. Through a series of internet, household, and water point surveys, this multidisciplinary study begins to address the question: does the proliferation of private boreholes strengthen or weaken the resilience of Lagos and its residents to future environmental shocks? A broad internet survey shows that 68% of 500 respondents make use of private boreholes on a daily basis, either as their primary water source or used conjunctively with other sources. Attitudes to groundwater are overwhelmingly positive, with a majority considering this a reliable source in terms of quality and quantity, and agreeing that access to a private borehole increases households’ water security, helping families to cope with possible water shortages in future. The majority of borehole owners perceive no risks associated with long-term groundwater availability, with 89% agreeing that water is abundant and 86% holding the view that borehole owners should be able to abstract as much water as they like. The results of a focused water-point and household survey, carried out at 40 private groundwater sources across Lagos, agree with these findings. Of those surveyed, the majority derive their domestic water from privately owned hand-dug wells and boreholes, and sachet water. Water point users have positive perceptions of the water quality from these sources, with 90% of boreholes and 80% of hand-dug wells thought to provide good quality water. However, water quality analyses show that individual’s perceptions do not always reflect reality. One third of boreholes and over 80% of shallow wells surveyed display unsafe levels of E. Coli. Of those sources perceived as good quality, almost 40% are classed as unsafe for drinking, according to measured levels of E. Coli. The collective enthusiasm for unlimited and expanding groundwater extraction in the city of Lagos coupled with a demonstrated lack of groundwater governance and regulation, while increasing individuals’ resilience to issues of water shortage in the present, may decrease the resilience of the wider community in the long-term. Understanding the role of agency and communicating the potential risks associated with uncontrolled groundwater development, across a range of actors and agencies, may be critical to avoid future conflict between individual and societal resilience to environmental shocks