Teaching of Force and Motion Concepts through Game-Based Physical Activities at Elementary Level

Bu çalışmanın amacı, oyun temelli fiziksel etkinlikler yoluyla kuvvet ve hareket kavramlarının öğretimine dayalı etkinliklerin etkisini tespit etmektir. Çalışmaya 3. ve 4. sınıfa geçecek toplam 21 ilkokul öğrencisi katılmıştır. Araştırmada bağımlı değişken kuvvet ve hareket kavramları üzerine odaklanan fen akademik başarısıdır. Bu araştırma nicel araştırma yöntemlerinden tek gruplu öntest-sontest modeline göre desenlenmiştir. Denel işlemden önce öğrencilere kuvvet başarı testi öntest olarak verilmiştir. Daha sonra kuvvet ve hareket kavramlarının öğretimi için geliştirilen sekiz etkinlikten oluşan denel işlem gerçekleştirilmiştir. Denel işlemden sonra öğrencilere kuvvet başarı testi sontest olarak uygulanmıştır. Denel işlemde öğrenciler her gün 1.5 saatlik sürede iki etkinliğe katılmışlardır. Çalışma toplam dört gün sürmüştür. Araştırmacılar tarafından hazırlanan başarı testinden elde edilen veriler Wilcoxon İşaretli-sıralar testi ile analiz edilmiştir. Analiz sonucu, öğrencilerin kuvvet başarı testinden aldıkları deney öncesi ve sonrası puanları arasında anlamlı bir fark olduğunu göstermiştir (z=3.23; p<.05). Bu sonuca dayalı olarak bazı önerilerde bulunulmuştur.The purpose of this study was to determine effect of the treatment based on teaching force and motion concepts through game-based physical activities. A total of 21 elementary school students from 3rdand 4th grades were participated in the study. The dependent variable was science achievement that was focused on force and motion concepts. The current study was designed as the one-group pretest-posttest model that is one of the quantitative research methods. Before the treatment students were given force achievement test as pretest. Then, students were given the treatment that included eight physical activities through which force and motion concepts were taught. After the treatment, force achievement test was given as posttest to the students. Students were introduced two activities that took one and half hours in each day during the treatment. The duration of the treatment was four days. The data obtained from the science achievement test developed by the researchers were analyzed by the Wilcoxon signed-rank test. The analysis indicated there was a statistically significant difference between students' pretest and posttest scores (z=3.23, p&lt;.05). Some suggestions were made based on the result

Açıklanamayan İnfertilite Nedeniyle İntrauterin İnseminasyon Uygulanan Hastalarda Ejakülattaki Preapoptotik Sperm Oranının İntrauterin İnseminasyon Başarısındaki Etkisinin Araştırılması

We hypothesis that the apoptotic sperm in ejaculate may be responsible for failure of intrauterine insemination in infertile couples and also may play a role on the etiology of unexplained infertility.This study includes the patients who consulted Hacettepe University Faculty of Medicine, Department of Obstetrics and Gynecology, Reproductive Endocrinology, Infertility and Andrology Unit between March 2012 - December 2012 and were undergoing ovulation induction and intrauterine insemination with diagnosis of unexplained infertility.In this study, the ejaculate from patients is stained with annexin V kit (Annexin V-FITC Apoptozis Detection Kit-Santa Cruz Biotechnology) after prepared by the density gradient centrifugation (DGS) method to determine the sperm proapoptotic rate and its relation to pregnancy outcome. The results of the patients who achieved pregnancy are compared to the results of the patients who couldn't achieve pregnancy. This study included 94 patients for whom ovulation induction was performed using rFSH due to unexplained infertility. The pregnancy rate of those 94 patients was 13.8% (n=13). The samples taken from subfertile men ejaculate were stained with annexin V after washing and were examined under immunofluorescence microscope. Annexin V-positive sperm rate was found as approximately 20.03% ± 13.73 (1-70). Annexin V-positive sperm rate has been found lesser among the patients who achieved pregnancy (15.69%) when compared to the patients who didn't achieve pregnancy (20.72%). However, the difference was not statically significant (p=0.17).İnfertil çiftlerde, olumsuz intrauterin inseminasyon sonuçlarının bir bölümünden ejakülattaki apoptotik spermlerin sorumlu olabileceği ve açıklanamayan infertilite etyolojisinde ejakülattaki apoptotik spermlerin rolünün de olabileceği düşünülerek bu çalışma planlanmıştır. Mart 2012-Aralık 2012 tarihleri arasında, Hacettepe Üniversitesi Tıp Fakültesi, Kadın Hastalıkları ve Doğum Anabilim Dalı, Üreme Endokrinolojisi, İnfertilite ve Androloji Ünitesine başvuran ve açıklanamayan infertilite tanısı konularak ovulasyon indüksiyon ve intrauterin inseminasyon uygulanacak hastalar araştırma kapsamına alınmıştır. Bu çalışmada, hastalardan alınan ejakulat dansite gradient santrifügasyon (DGS) yöntemi ile hazırlandıktan sonra annexin V ticari kiti ( Annexin V- FITC Apoptoz Saptama Kiti -Santa Cruz Biotechnology) ile boyanarak preapoptotik sperm oranı saptandıktan sonra bunun gebelik sonuçları ile ilişkisi değerlendirilmiştir. Gebelik elde edilen hastaların sonuçları gebelik elde edilemeyen hastaların sonuçları ile karşılaştırılmıştır. Açıklanamayan infertilite nedeniyle rFSH kullanılarak ovulasyon indüksiyon ve intrauterin inseminasyon yapılan 94 hasta çalışmaya alınmıştır. Araştırma grubundaki 94 hastanın intrauterin inseminasyon sonucu gebelik oranları %13.8 (n:13) olarak bulunmuştur. Araştırma grubuna dahil edilen subfertil erkeklerin semenlerinden yıkama sonrası alınan örnek annexin V ile boyanıp immünfloresan mikroskopta incelendi ve annexin V pozitif sperm oranı ortalama %20.03±13.73(1-70) olarak bulundu. Gebe kalan gruptaki hastaların sperm örneklerinde annexin V pozitif sperm oranı(%15.69), gebe kalamayan gruba(%20.72) göre daha düşük bulunmuştur ancak aradaki fark istatiksel olarak anlamlı bulunmamıştır(p=0.1

Adnexal Torsion in the Third Trimester of Pregnancy After in Vitro Fertilization: A Case Report

Adnexal torsion causes venous and lymphatic blockade complicated by congestion. Adnexal torsion is seldom in pregnancy, occuring approximately 1 in 5000 pregnancies, more frequently in the first trimester. Acute abdominal pain and abdominal disturbances are challenging issues during pregnancy for the diagnosis. The clinical symptoms are non-specific. Colour and power Doppler sonography may be useful for the early diagnosis. Adnexal torsion is generally due to ovarian stimulation treatment or ovarian masses in pregnancy. The correct diagnosis of maternal ovarian torsion might be delayed or underestimated in the second half of gestation because the increased dimensions of the uterus could blockade the abdominal palpation and make the sonography inefficient. Laparoscopy should be preferable for the adnexal torsion suspicion. But as the gestational age increases laparotomy should be a choice because of the risk of injury to the uterus related to the enlarged volume by the fetus

Isolated Fallopian Tube Torsion in a Virgin Patient: A Case Report

The twisting of the adnexa; partially or totally around its vascular axis and causing hemorrhagic infarction is called adnexal torsion. Isolated torsion of the fallopian tube is a rare and uncommon pathology that has an incidence as 1 in 1.5 million women especially in the reproductive age. Here we describe an isolated torsion of the fallopian tube case with chronic pelvic pain

Laparoscopic-assisted Vecchietti Procedure for Creation of Neovagina in Mayer-Rokitansky-Küster-Hauser Syndrome: Analysis of Two Cases

The aim of this study was to review the application of Vecchietti’s principles to laparoscopy for the creation af neovagina in patients diagnosed with Rokitansky syndrome, the functional and psychological outcomes. A functioning neovagina was performed in both of the subjects. The subjects which are sexually active noted satisfactory intercourse with significant improvements in self-confidence, self-esteem and general well-being in first 6 months follow-up

Stage Iiic Transitional Cell Carcinoma And Serous Carcinoma Of The Ovary Have Similar Outcomes When Treated With Platinum-Based Chemotherapy

Objective: Previous studies reported better outcomes for transitional cell carcinoma (TCC) of the ovary when compared with more common histologic types such as serous epithelial ovarian cancers (EOCs). The aim of this study was to compare the survival outcomes of platinum- based chemotherapy in patients with stage IIIC TCCs and serous EOCs. Material and Methods: Clinicopathologic features and survival data of patients with FIGO stage IIIC TCC and serous EOC who had undergone primary surgery followed by six cycles of intravenous platinum/taxane between 2007 and 2015 were retrieved from the database of Hacettepe University Hospital. Results: We identified 14 (10.9%) TCCs and 114 (89.1%) serous EOCs. The median follow-up duration was 28 months (range, 3-101 months). Univariate analysis revealed that the TCCs and serous EOCs had similar progression-free survival (PFS) and overall survival (OS). Patients with residual disease less than 1 cm had longer OS than patients with residual disease greater than 1 cm (75.0 vs. 45.0 months, p=0.012). Cox regression analysis of all potential prognostic factors showed that the only independent prognostic factor significantly associated with OS was residual disease less than 1 cm [hazard ratio=0.38; 95% confidence interval: (0.19-0.77); p=0.007]. Conclusion: Surgically treated advanced stage TCCs did not have a significantly better prognosis after platinum/taxane-based chemotherapy when compared with serous EOCs. Residual tumor volume after primary surgery was the only independent predictor of OS in patients with EOC. Our results demonstrate the significance of achieving optimal cytoreduction in all histologic subtypes of EOC.PubMedScopu

Does Preoperative Diagnosis of Endometrial Hyperplasia Necessitate Intraoperative Frozen Section Consultation?

Background: In women with endometrial hyperplasia, there is a risk for co-existent endometrial cancer when patients are subjected to immediate surgical treatment. Aims: The aim of this study was to investigate the frequency of endometrial cancer and the accuracy of frozen section analysis at the time of hysterectomy among patients with endometrial hyperplasia, to reveal whether or not a preoperative diagnosis of endometrial hyperplasia necessitates frozen section consultation. Study Design: Retrospective cross-sectional study. Methods: A department database review was performed to identify patients who were subjected to hysterectomy with a preoperative diagnosis of endometrial hyperplasia, during the period from 2007 to 2014. Results: The study group included 189 cases. The final pathological examination revealed endometrial cancer in 16 women (8.4%). The risk of cancer in patients with endometrial hyperplasia was 1 of 125 (0.8%) in simple hyperplasia without atypia, 1 of 21 (4.8%) in complex hyperplasia without atypia and 14 of 43 (32.5%) in atypical hyperplasia. Of women with cancer, 2 of 16 (12.5%) had high-risk features. Frozen section analysis was requested in 46 cases. Frozen sections helped to identify six out of 11 cases of endometrial cancer (54.5%). The sensitivity, specificity and positive and negative predictive values of frozen section analysis for the detection of endometrial cancer among women with endometrial hyperplasia were 54.4%, 97.2%, 85.7% and 87.5%, respectively. Conclusion: Although a significant proportion of patients with atypical endometrial hyperplasia are diagnosed with endometrial cancer following hysterectomy, most of these cases have low-risk features and do not require surgical staging. Additionally, intraoperative frozen section analysis if not helpful for diagnosing concurrent endometrial cancer in patients with endometrial hyperplasia. Therefore, it seems that patients with endometrial hyperplasia can be operated upon in settings with no available method for obtaining frozen sections intraoperatively.WoSScopu

Brain Metastasis as an Initial Manifestation of Ovarian Carcinoma: A Case Report

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