Performance of the CLEO III LiF-TEA Ring Imaging Cherenkov Detector in a High Energy Muon Beam

The CLEO III Ring Imaging Cherenkov detector uses LiF radiators to generate Cherenkov photons which are then detected by proportional wire chambers using a mixture of CH$_4$ and TEA gases. The first two photon detector modules which were constructed, were taken to Fermilab and tested in a beam dump that provided high momentum muons. We report on results using both plane and sawtooth shaped radiators. Specifically, we discuss the number of photoelectrons observed per ring and the angular resolution. The particle separation ability is shown to be sufficient for the physics of CLEO III

Successful Treatment of Ibrutinib-Associated Central Nervous System Hemorrhage with Platelet Transfusion Support

Ibrutinib is a novel targeted therapy for B-cell malignancies. Hemorrhagic events were reported in the original trials, however the mechanism of bleeding is just being elucidated. Recent studies have demonstrated platelet dysfunction as a mechanism of bleeding. Currently we report two patients who developed life-threatening central nervous system hemorrhage while receiving ibrutinib for chronic lymphoid leukemia (CLL) and mantle cell lymphoma, respectively. Both patients improved rapidly after platelet transfusions even though their platelet counts were normal or only mildly reduced at the time of hemorrhage. We suggest that platelet transfusions can ameliorate the platelet dysfunction defect of ibrutinib and can support the patient through the critical period until new platelet production occurs

Stroke following percutaneous coronary intervention : type-specific incidence, outcomes and determinants seen by the British Cardiovascular Intervention Society 2007-12

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2015. For permissions please email: [email protected] reviewedPostprin

The CLEO-III Ring Imaging Cherenkov Detector

The CLEO-III Detector upgrade for charged particle identification is discussed. The RICH design uses solid LiF crystal radiators coupled with multi-wire chamber photon detectors, using TEA as the photosensor, and low-noise Viking readout electronics. Results from our beam test at Fermilab are presented.Comment: Invited talk by R.J. Mountain at ``The 3rd International Workshop on Ring Imaging Cherenkov Detectors," a research workshop of the Israel Science Foundation, Ein-Gedi, Dead-Sea, Israel, Nov. 15-20, 1998, 14 pages, 9 figure

Deep Underground Neutrino Experiment (DUNE) near detector conceptual design report

The Deep Underground Neutrino Experiment (DUNE) is an international, world-class experiment aimed at exploring fundamental questions about the universe that are at the forefront of astrophysics and particle physics research. DUNE will study questions pertaining to the preponderance of matter over antimatter in the early universe, the dynamics of supernovae, the subtleties of neutrino interaction physics, and a number of beyond the Standard Model topics accessible in a powerful neutrino beam. A critical component of the DUNE physics program involves the study of changes in a powerful beam of neutrinos, i.e., neutrino oscillations, as the neutrinos propagate a long distance. The experiment consists of a near detector, sited close to the source of the beam, and a far detector, sited along the beam at a large distance. This document, the DUNE Near Detector Conceptual Design Report (CDR), describes the design of the DUNE near detector and the science program that drives the design and technology choices. The goals and requirements underlying the design, along with projected performance are given. It serves as a starting point for a more detailed design that will be described in future documents