Which “Greenness” is Valued? Evidence from Green Condominiums in Tokyo

This is one of the first researches on price differentials of green buildings in Asia. Using a rich set of data on condominium transactions and mandatory evaluation of environmental performance in Tokyo, we estimate the effects of itemized green scores on transaction prices. Although green condominiums are on average traded at a premium, the premium is mainly attributed to the building age and quality. After controlling for relevant attributes, we find significant price discounts for newly constructed green condominiums. However, green condominiums experience little depreciation at least during the initial years. Using itemized scores, we find that the long-life design mitigates price discounts, but other factors such as the use of eco-friendly materials, renewable energy, water reuse, and greening exacerbate discounts. Several possibilities are discussed including high future maintenance costs of green condominiums.sustainability; green building; hedonic pricing; transaction price; residential real estate; Japan

Role of MCP‐1 and MIP‐1α in retinal neovascularization during postischemic inflammation in a mouse model of retinal neovascularization

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141957/1/jlb0137.pd

MP-6 Coccidiosis Intestinal Dysmotility in C57BL/6 Mice

Recently, anecdotal report was arisen that coccidiosis in cattle resulted in delayed intestinal motility. The occurrence of delayed intestinal motility has been never briefly reported. However, some study indicated a delay in intestinal motility. A study in cattle coccidiosis reported a transient increase of nutrients apparent digestibility, especially of crude fiber index, during clinical coccidiosis and that anorexia and intestinal leakage impaired the nitrogen balance, causing weight depression. The observation may have reflected intestinal hypomotility, however, this work did not observe the intestinal motility directly. Another study indicated that Eimeria infection in rabbit could induce intestinal motility disturbance. The disturbance, however, did not indicate as general delay in intestinal transit, because some part of the intestine experienced faster motility and another part indicated slower motility.As one of the cosmopolitan diseases of production animal, the occurrence of intestinal dysmotility by coccidiosis need to be clarified. And a control measure against intestinal dysmotility of coccidiosis need to be proposed soon after the clarification of its clinical existence. Therefore, we designed a study with murine Eimeria as model to provide evidence for better approach toward this emerging issue

MP-11 Eimeria pragensis Induce Immune Mediated Intestinal Hypomotility in C57BL/6 Mice

The manifestation of intestinal dysmotility of coccidiosis has never been briefly reported before. From murine Eimeria study we concluded that Eimeria pragensis (Ep) is capable to induce intestinal hypomotility described to be similar to pan-enteric ileus.In comparison with the intestinal dysmotility in postoperative ileus which is orchestrated by TH1 immune response [1], a local injury to some part of intestine could trigger pan-enteric ileus. If the TH1 immune response could also be induced in Ep infection, the delay in intestinal motility could be explained as similar mechanism as the post-operative ileus. Since the Ep infestation occurred in the ileocecal part of the intestines, with similar mechanism of post-operative ileus, the pan-enteric ileus could be triggered. In this study, we tried to find a relationship between intestinal dysmotility and TH1 immune response in murine coccidiosis

Which “Greenness” is Valued? Evidence from Green Condominiums in Tokyo

This is one of the first researches on price differentials of green buildings in Asia. Using a rich set of data on condominium transactions and mandatory evaluation of environmental performance in Tokyo, we estimate the effects of itemized green scores on transaction prices. Although green condominiums are on average traded at a premium, the premium is mainly attributed to the building age and quality. After controlling for relevant attributes, we find significant price discounts for newly constructed green condominiums. However, green condominiums experience little depreciation at least during the initial years. Using itemized scores, we find that the long-life design mitigates price discounts, but other factors such as the use of eco-friendly materials, renewable energy, water reuse, and greening exacerbate discounts. Several possibilities are discussed including high future maintenance costs of green condominiums

Which “Greenness” is Valued? Evidence from Green Condominiums in Tokyo

This is one of the first researches on price differentials of green buildings in Asia. Using a rich set of data on condominium transactions and mandatory evaluation of environmental performance in Tokyo, we estimate the effects of itemized green scores on transaction prices. Although green condominiums are on average traded at a premium, the premium is mainly attributed to the building age and quality. After controlling for relevant attributes, we find significant price discounts for newly constructed green condominiums. However, green condominiums experience little depreciation at least during the initial years. Using itemized scores, we find that the long-life design mitigates price discounts, but other factors such as the use of eco-friendly materials, renewable energy, water reuse, and greening exacerbate discounts. Several possibilities are discussed including high future maintenance costs of green condominiums

Cell Type Specific Representation of Vibro-tactile Stimuli in the Mouse Primary Somatosensory Cortex

Although the processing of whisker deflections in the barrel area of the rodent primary somatosensory cortex (S1) has been studied extensively, how cutaneous vibro-tactile stimuli are processed in the rodent S1 outside the barrel area has not been fully examined. Particularly, the cell-type specific representation of multiple vibration frequencies in genetically identified inhibitory cells in the S1 has not been examined. Using two-photon calcium imaging, we examined the responses to vibration stimuli of excitatory and inhibitory neurons in the S1 hind limb area of male and female mice. The excitatory cells showed relatively sharp selectivity to vibration stimuli, whereas the inhibitory cells exhibited less selectivity. The excitatory and inhibitory cells with different preferred stimuli were intermingled in a “salt and pepper” manner. Furthermore, the noise correlation tended to be especially strong in excitatory-inhibitory and inhibitory-inhibitory cell pairs that have similar stimulus selectivity. These results suggest that excitatory cells tend to represent specific stimulus information and work together with similarly tuned inhibitory cells as a functionally connected network

Development of Power stock exercise for prevention of Locomotive Syndrome

要介護の危険性が高い状態であるロコモティブシンドロームの予防を目的としてストックやポールを活用した「パワー・ストック・エクササイズ」を開発した。この運動プログラムの特長は，健常な中高年者から後期高齢者，低体力者まで様々な体力レベルの方が実施可能なことである。ストックを利用することにより安全に運動することが出来，また運動負荷の調整も可能となる。さらに正しいフォームの獲得にも有効である。トレーニングメニューの中核は「フラミンゴバランス」と「カンガルー運動」と「カモシカステップ」で構成されている。これらの運動プログラムの実践によりバランス機能と筋力，ステップワークの改善が期待される。We developed the exercise program named 'Power stock exercise' for preventing locomotive syndrome. The strong point of this program is that the person of various physical strength levels can carry out. Even the elderly people to whom muscular power fell can practice the exercise. The strong point of this program is safety, and the 2nd strong point is being able to adjust the load of exercise. In addition, stock is utilizable also as an item for gaining the right training form. The main exercise consists of flamingo balance, kangaroo exercise, and antelope step. We think that they are effective in a balance function, the muscular power of the leg, and improvement in a step work. We will verify the effect of this exercise program from now on

Dendritic retraction, but not atrophy, is consistent in amyotrophic lateral sclerosis-comparison between Onuf’s neurons and other sacral motor neurons-

BACKGROUND: Fundamental cytological changes of amyotrophic lateral sclerosis (ALS) were looked for by comparing relatively preserved Onuf’s nucleus (ON) and severely affected neighboring motor neuron groups (dorsolateral alpha motoneurons (DL) and other anterior horn neurons (OAH)). The second sacral segments from 11 ALS patients and 5 controls were initially quadruple-labeled for phosphorylated and non-phosphorylated TAR DNA-binding protein of 43 kDa (TDP43), and p62 with DAPI to identify TDP43-related changes. After digital recording of these fluorescence data encompassing the entire specimen at a high resolution, the same sections were stained with Klüver-Barrera method to obtain their exact bright-field counterparts. This novel approach facilitated exact identification of ON. Furthermore, this cell to cell comparison enabled to correlate quantitative indices of the neuronal cell bodies: perimeter, area and circularity index (CI) i.e. the ratio of (perimeter/2π) divided by the square root of (area/π), which decreases with dendritic retraction, overall number of neurons and inclusions. RESULTS: In addition to known preservation of ON neuron number relative to DL and OAH, size reduction of ON neurons was not significant even in the advanced stage. Significant size reduction in DL was counteracted in the presence of TDP43-positive inclusions. Early increase of neuronal size in OAH was further enhanced by the presence of TDP43-positive inclusions. Even with these heterogeneous cytopathological changes, a decrease in CI was consistent in all groups at an early phase and was correlated with neuronal loss. CONCLUSIONS: Among variable cytological changes of ALS, a decrease in CI is a consistent early feature shared between non-atrophic ON neurons and other anterior horn neurons with either decreased (DL) or even increased (OAH) size and profounder neuronal loss. This decrease in CI, representative of dendritic retraction, is fundamental to ALS pathogenesis, not necessarily linked to cell size and pathological inclusions