15 research outputs found
Bone eQTL data (R/qtl format)
Residual bone and fecundity phenotypes (adjusted for body weight), preprocessed gene expression data and genotypes of the 127 individuals of the bone eQTL study in R/qtl csv input format
Comb eQTL data (R/qtl format)
Residual comb masses, preprocessed gene expression data and genotypes of the 39 individuals of the comb eQTL study in R/qtl csv input format
Bone microarray data (raw and RMA preprocessed)
Microarray data for the 127 individual bone samples. This files contains the raw as well as RMA preprocessed gene expression values, and design files for the custom NimbleGen gene expression chip used
RJF x OS genetic map (QTL Express format)
Genetic map file for the Red Junglefowl x Obese strain White Leghorn intercross in QTL Express format
RJF x OS genotypes (QTL Express format)
Genotype data from the Red Jungefowl x Obese strain White Leghorn intercross in QTL Express format
RJF x OS bone phenotypes (QTL express format)
Bone phenotypes (residual values after adjusting for body weight) from the Red Junglefowl x Obese strain White Leghorn intercross in QTL Express format
Additional fecundity and bone morphometric traits correlated with <i>HAO1</i> and <i>BMP2</i> expression in bone samples.
<p>Genotype (QTL) effect and body weight were included in each GLM.</p
General Linear Model results for gene expression and QTL effect on comb mass.
<p>All variables were modelled on comb mass, with the t-statistic and p-value shown for each variable included in each of the models (shown as t-statistic/p-value). ‘-’ is used to indicate where a variable is not included in that particular model. AIC stands for the Akaike Information Criterion of each model. A full description of each model is given in the methods section.</p
Identified Biomarkers for the Risk of Developing Type 2 Diabetes.
<p>The length of bars denotes total number of incident type 2 diabetes cases across all studies for each biomarker.</p
Chromosome 3 QTL peaks and confidence intervals (C.I.) from the F<sub>2</sub>-L13 (blue line) and F<sub>8</sub>-L13 (dark red line) crosses.
<p>In the case of the F<sub>2</sub>-L13, the horizontal arrow indicates the 1.8 LOD drop C.I. of the QTL position. The location of the F<sub>8</sub>-L13 C.I. has been expanded below the graph to show the location of the two candidate genes and the selective sweep, and the overlap with the F<sub>2</sub>-L13 C.I.</p