7,727 research outputs found
Microwave Spectroscopy
Contains a report on a research project.Lincoln Laboratory (Purchase Order DDL B-00368)United States ArmyUnited States NavyUnited States Air Force (Contract AF19(604)-7400
Microwave Spectroscopy
Contains reports on two research projects.Joint Services Electronics Programs (U. S. Army, U.S. Navy, and U.S. Air Force) under Contract DA 36-039-AMC-03200(E
Microwave Spectroscopy
Contains reports on two research projects.Lincoln Laboratory (Purchase Order DDL BB-107)United States ArmyUnited States NavyUnited States Air Force (Contract AF19(604)-7400
Microwave Spectroscopy
Contains reports on two research projects.Lincoln Laboratory, Purchase Order DDL B-00368U. S. ArmyU. S. NavyU. S. Air Force under Air Force Contract AF19(604)-740
A Paraconsistent Higher Order Logic
Classical logic predicts that everything (thus nothing useful at all) follows
from inconsistency. A paraconsistent logic is a logic where an inconsistency
does not lead to such an explosion, and since in practice consistency is
difficult to achieve there are many potential applications of paraconsistent
logics in knowledge-based systems, logical semantics of natural language, etc.
Higher order logics have the advantages of being expressive and with several
automated theorem provers available. Also the type system can be helpful. We
present a concise description of a paraconsistent higher order logic with
countable infinite indeterminacy, where each basic formula can get its own
indeterminate truth value (or as we prefer: truth code). The meaning of the
logical operators is new and rather different from traditional many-valued
logics as well as from logics based on bilattices. The adequacy of the logic is
examined by a case study in the domain of medicine. Thus we try to build a
bridge between the HOL and MVL communities. A sequent calculus is proposed
based on recent work by Muskens.Comment: Originally in the proceedings of PCL 2002, editors Hendrik Decker,
Joergen Villadsen, Toshiharu Waragai (http://floc02.diku.dk/PCL/). Correcte
Comparison of the Interactions of Transferrin Receptor and Transferrin Receptor 2 with Transferrin and the Hereditary Hemochromatosis Protein HFE
The transferrin receptor (TfR) interacts with two proteins important for iron metabolism, transferrin (Tf) and HFE, the protein mutated in hereditary hemochromatosis. A second receptor for Tf, TfR2, was recently identified and found to be functional for iron uptake in transfected cells (Kawabata, H., Germain, R. S., Vuong, P. T., Nakamaki, T., Said, J. W., and Koeffler, H. P. (2000) J. Biol. Chem. 275, 16618-16625). TfR2 has a pattern of expression and regulation that is distinct from TfR, and mutations in TfR2 have been recognized as the cause of a non-HFE linked form of hemochromatosis (Camaschella, C., Roetto, A., Cali, A., De Gobbi, M., Garozzo, G., Carella, M., Majorano, N., Totaro, A., and Gasparini, P. (2000) Nat. Genet. 25, 14-15). To investigate the relationship between TfR, TfR2, Tf, and HFE, we performed a series of binding experiments using soluble forms of these proteins. We find no detectable binding between TfR2 and HFE by co-immunoprecipitation or using a surface plasmon resonance-based assay. The affinity of TfR2 for iron-loaded Tf was determined to be 27 nM, 25-fold lower than the affinity of TfR for Tf. These results imply that HFE regulates Tf-mediated iron uptake only from the classical TfR and that TfR2 does not compete for HFE binding in cells expressing both forms of TfR
Microwave Spectroscopy
Contains report on one research project.Joint Services Electronics Programs (U.S. Army, U.S. Navy, and U.S. Air Force) under Contract DA 36-039-AMC-03200(E
Plasma Physics
Contains reports on three research projects.U. S. Atomic Energy Commission (Contract AT(30- 1)- 1842
Microwave Spectroscopy
Contains reports on four research projects.Joint Services Electronics Programs (U. S. Army, U. S. Navy, and U. S. Air Force) under Contract DA 36-039-AMC-03200(E
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