“Alice” – A Social Media Journey - Directed by Louise Cooke-xxnPzHQXrRI.mp4

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  Alice was directed by Louise Cooke<div><br></div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.This film was made entirely from social media data and was made as part of the EPSRC ReelLives project <div><br></div

The Baristacrat - Directed by Gus Melton.mp4

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  The Baristacrat was directed by Gus Melton.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

The Public Life of Manick G - Directed by Meghan Horvath.mp4

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  Cumulus was directed by Chris Smith.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

Peter Tatchell - Directed by Peter Fraser.mp4

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  Peter Tatchell was directed by Peter Fraser.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

Everyone is Waiting for Something to Happen - Directed by Emma Calder.mp4

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.   Everybody is Waiting for Something to Happen was directed by Emma Calder.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

Cumulus

This film was made as part of the ReelLives research project which explores our digital identity.  Six short films were commissioned which were made entirely from the subject's social media data and allowed us to think about who we are online.  Cumulus was directed by Chris Smith.<div><br></div><div>The research was covered by University of Birmingham Research Ethics Committee ERN_15-0572. To adhere to ethical guidelines, all data used was approved by the participants.</div

Codon usage bias reveals genomic adaptations to environmental conditions in an acidophilic consortium

<div><p>The analysis of codon usage bias has been widely used to characterize different communities of microorganisms. In this context, the aim of this work was to study the codon usage bias in a natural consortium of five acidophilic bacteria used for biomining. The codon usage bias of the consortium was contrasted with genes from an alternative collection of acidophilic reference strains and metagenome samples. Results indicate that acidophilic bacteria preferentially have low codon usage bias, consistent with both their capacity to live in a wide range of habitats and their slow growth rate, a characteristic probably acquired independently from their phylogenetic relationships. In addition, the analysis showed significant differences in the unique sets of genes from the autotrophic species of the consortium in relation to other acidophilic organisms, principally in genes which code for proteins involved in metal and oxidative stress resistance. The lower values of codon usage bias obtained in this unique set of genes suggest higher transcriptional adaptation to living in extreme conditions, which was probably acquired as a measure for resisting the elevated metal conditions present in the mine.</p></div

Hierarchical clustering of 10 biomining bacteria according to CIB values grouped by COG category.

<p><b>A.</b> Conserved genes, <b>B.</b> Unique genes. For each strain, the mean value of CIB was calculated for genes (both conserved and unique) within each COG category. The strains were then hierarchically clustered using average linkage with the Pearson product correlation coefficient measuring the distance between the vectors of mean CIB per COG category. The color bar ranges from green (low CIB, 0.0) to red (high CIB, 0.5).</p

Unique genes from the consortium involved in copper bioleaching with the smallest CIB values.

<p>Unique genes from the consortium involved in copper bioleaching with the smallest CIB values.</p

Average value of CIB for genes belonging to ten strains of bacteria (consortium and non-consortium) and the COG database binned by gene length in bases.

<p>Each bin contains genes from <i>ℓ</i>-499 to <i>ℓ</i> bases in length, where <i>ℓ</i> can be read off the x-axis. The y-axis indicates the mean value of CIB for genes belonging to the bin indicated on the x-axis. Bacterial strains belonging to the same species are plotted using the same point shape. Strains belonging to the biomining consortium are distinguished by filled points linked by solid lines while non-consortium strains are hollow points linked by dotted lines. The average CIB values for the 2014 COG database are plotted as crosses linked by a red solid line.</p