Recent advances in the design of water based-flame retardant coatings for polyester and polyester-cotton blends

Over the last ten years a new trend of research activities regarding the flame retardancy of polymeric materials has arisen. Indeed, the continuous search for new flame retardant systems able to replace the traditional approaches has encouraged alternative solutions, mainly centred on nanotechnology. In this context, the deposition of nanostructured coatings on fabrics appears to be the most appealing and performance suitable approach. To this aim, different strategies can be exploited: from the deposition of a single monolayer consisting of inorganic nanoparticles (single-step adsorption) to the building-up of more complex architectures derived from layer by layer assembly (multi-step adsorption). The present paper aims to review the application of such systems in the field of polyester and polyester-cotton blend fabrics. The results collated by the authors are discussed and compared with those published in the literature on the basis of the different deposition methods adopted. A critical analysis of the advantages and disadvantages exhibited by these approaches is also presented

Reuse and valorisation of hemp fibres and rice husk particles for fire resistant fibreboards and particleboards

The present manuscript deals with the reuse and valorisation of agricultural wastes and by-products (namely, hemp fibres and rice husk particles) to produce fire retardant fibreboards and particleboards for applications in biobuilding. Since fire retardancy is one of the most important challenges, a detailed study on the thermal and flame retardant properties of the above materials assembled using starch as the binder and different ammonium dihydrogen phosphate contents as fire retardant agents, is proposed. The combustion properties have been investigated in developing fire conditions, employing a radiating heat flux of 35 kW/m2 generated by a cone calorimeter. An optimised formulation able to make both fibreboards and particleboards not ignitable has been found and is predicted to be “A2/B” class in the European fire classification for building products. The resultant materials have proven to undergo pyrolysis and not to burn, favouring the formation of a dense and consistent final residue

L-Arginine-Derived Polyamidoamine Oligomers Bearing at Both Ends beta-Cyclodextrin Units as pH-Sensitive Curcumin Carriers

The aza-Michael polyaddition of L-arginine and N,N′-methylene-bis-acrylamide gives the biocompatible and easily cell-internalized polyamidoamine ARGO7. By controlled synthesis, two ARGO7 oligomers, namely a trimer and a pentamer, bearing acrylamide terminal units, were obtained as precursors of the β-cyclodextrin-end-terminated oligomers P3 and P5, which have been shown to encapsulate curcumin at both pH 7.4 and 4.5. After lyophilization, P3- and P5-curcumin complexes gave stable water solutions. The apparent solubility of encapsulated curcumin was in the range 20–51 μg mL(−1), that is, three orders of magnitude higher than the water solubility of free curcumin (0.011 μg mL(−1)). The drug release profiles showed induction periods both at pH levels 4.5 and 7.4, suggesting a diffusive release mechanism, as confirmed by kinetic studies. The release rate of curcumin was higher at pH 7.4 than at pH 4.5 and, in both cases, it was higher for the P5 complex. Encapsulated curcumin was more photostable than the free drug. Molecular mechanics and molecular dynamics simulations explain at atomistic level the formation of aggregates due to favorable van der Waals interactions. The drug molecules interact with the external surface of carriers or form inclusion complexes with the β-cyclodextrin cavities. The aggregate stability is higher at pH 4.5

pH-Dependent Chiral Recognition of D- and L-Arginine Derived Polyamidoamino Acids by Self-assembled Sodium Deoxycholate

D- and L-arginine-based polyamidoamino acids, called D- and L-ARGO7, retain the chirality and acid/base properties of the parent -amino acids and show pH-dependent self-structuring in water. The ability of the ARGO7 chiral isomers to selectively interact with chiral biomolecules and/or surfaces was studied by choosing sodium deoxycholate (NaDC) as a model chiral biomolecule for its ability to self-assembly into globular micelles, showing enantio-selectivity. To this purpose, mixtures of NaDC with D-, L- or D,L-ARGO7, respectively, in water were analysed by circular dichroism (CD) spectroscopy and small-angle neutron scattering (SANS) at different levels of acidity expressed in terms of pD and concentrations. Differences in the CD spectra indicated chiral discrimination for NaDC/ARGO7 mixtures in the gel phase (pD 7.30) but not in the solution phase (pD 9.06). SANS measurements confirmed large scale structural perturbation induced by this chiral discrimination in the gel phase yet no modulation of the structure in the solution phase. Together, these techniques shed light on the mechanism by which ARGO7 stereoisomers modify the morphology of NaDC micelles as a function of pH. This work demonstrates chirality-dependent interactions that drive structural evolution and phase behaviour of NaDC, opening the way for designing novel smart drug delivery systems

Black Holes in Pseudobulges and Spheroidals: A Change in the Black Hole-Bulge Scaling Relations at Low Mass

We investigate the relationship between black hole mass and host galaxy properties for active galaxies with the lowest black hole masses currently known in galaxy nuclei. Hubble Space Telescope imaging confirms that the host galaxies have correspondingly low luminosity; they are ~1 mag below L*. In terms of morphology, ~60% of the members of the sample are disk-dominated, and all of these are consistent with containing a bulge or (more likely) pseudobulge, while the remainder are compact systems with no discernible disk component. In general the compact components of the galaxies do not obey the fundamental plane of giant elliptical galaxies and classical bulges, but rather are less centrally concentrated at a given luminosity, much like spheroidal galaxies. Our results strongly confirm that a classical bulge is not a requirement for a nuclear black hole. At the same time, the observed ratio of black hole to bulge mass is nearly an order of magnitude lower in this sample than that seen for classical bulges. While the M-sigma relation appears to continue to low mass, it seems that black hole-galaxy scaling relations do depend on galaxy structure.Comment: to appear in ApJ; 22 pages; 8 figures; original version available at http://www.astro.princeton.edu/~jgreene/paper.pd