Florid cemento osseous dysplasia and dentygerous cyst in a patient with apert syndrome: A case report

Apert syndrome is a rare congenital malformation characterized by craniocinocytosis, craniofacial anomalies and symmetric syndactyly of the feet and hands. Oral manifestations of Apert syndrome usually represents bifid uvula, malposition of the teeth, severe open bite, tooth decay and periodontal diseases. Fluorid cemento-osseous dysplasia is usually asymptomatic slow-growing non-neoplastic fibro-osseous lesions. Lesions are detected by routine radiographic examination. The aim of this case report is to present dentigerous cyst and florid cemento-osseous displasia in a patient with Apert syndrome. A 38-year-old female patient with a history of Apert syndrome referred to Marmara University, Faculty of Dentistry, Clinic of Oral and Dentomaxillofacial Radiology due to pain and swelling. On panoramic radiography, unilocular, hyperdense lesion with regular borders was observed in the anterior region of the mandible. Cone-beam computed tomography (CBCT) was performed for further examination of the lesion and perforation of buccal bone cortex was seen. Additionally, a regular monolocular hypodense lesion was observed in the anterior region of maxilla. A biopsy was performed to examine the lesion histopathologically. Histopathologic examination was performed to evaluate the lesions and the lesion in the mandible was diagnosed as cemento-osseous dysplasia. Because the lesion was multifocal, it was considered and compatible with fluoride cemento-osseous dysplasia. The lesion in the maxilla was diagnosed as dentigerous cyst on histopathologic examination. The diagnosis of fluoride cemento-osseous dysplasia is established by definite radiological and histopathological evaluation. In asymptomatic cases of fluorid cemento-osseous dysplasia, treatment is not required but patients should be followed up regularly. Practitioners should take into consideration the oral and dental findings in patients with Apert syndrome which rarely appear.KEYWORDS Apert Syndrome, florid cementoosseous dysplasia, dentigerous cys

Odontogenic cysts with sebaceous glands: 4 unusual cases.

Jaw cysts with sebaceous elements are unusual. Four cases of developmental odontogenic cyst associated with sebaceous glands are reported. Two of the cases were parakeratinized odontogenic keratocysts (Keratocystic odontogenic tumor) and two were orthokeratotic odontogenic keratocysts (Orthokeratinized odontogenic cyst). Two patients were female and two were male. One of these cases was in the second decade, two were in the third decade and one was in the sixth decade. All cysts were in the mandible. Three of the lesions were located in the posterior region including mandibular ramus; one was located between the right first molar and the left canine teeth, including embedded right canine. Some authors claim that cysts with sebaceous elements are intraosseous counterpart of dermoid cysts and refuse theories of their odontogenic origin. Whereas all of our lesions were odontogenic developmental cysts, we observed sebaceous glands within, subjacent or distant to epithelial lining in some areas

Glandular odontogenic cyst: Case series

WOS: 000418325600026PubMed ID: 29326523Glandular odontogenic cyst (GOC) is an uncommon and aggressive jaw cyst with a high recurrence rate. It may grow into a large size. Diagnosis of the cyst is challenging since it may be confused with some other jaw cysts and malignancies. Treatment methods vary from conservative surgery to radical bone resection. In this case series, we briefly present five cases of GOC diagnosed and treated at our clinic. Thorough histopathological diagnosis and long-term follow-up are necessary in patients with GOC