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Chapter 9 Gene Drive Strategies for Population Replacement
Gene drive systems are selfish genetic elements capable of spreading into a population despite a fitness cost. A variety of these systems have been proposed for spreading disease-refractory genes into mosquito populations, thus reducing their ability to transmit diseases such as malaria and dengue fever to humans. Some have also been proposed for suppressing mosquito populations. We assess the alignment of these systems with design criteria for their safety and efficacy. Systems such as homing endonuclease genes, which manipulate inheritance through DNA cleavage and repair, are highly invasive and well-suited to population suppression efforts. Systems such as Medea, which use combinations of toxins and antidotes to favor their own inheritance, are highly stable and suitable for replacing mosquito populations with disease-refractory varieties. These systems offer much promise for future vector-borne disease control
Thermal Quench at Finite t'Hooft Coupling
Using holography we have studied thermal electric field quench for infinite
and finite t'Hooft coupling constant. The set-up we consider here is D7-brane
embedded in ( corrected) AdS-black hole background. It is well-known
that due to a time-dependent electric field on the probe brane, a
time-dependent current will be produced and it will finally relax to its
equilibrium value. We have studied the effect of different parameters of the
system on equilibration time. As the most important results, we have observed a
universal behaviour in the rescaled equilibration time in the very fast quench
regime for different values of the temperature and correction
parameter. It seems that in the slow quench regime the system behaves
adiabatically. We have also observed that the equilibration time decreases in
finite t'Hooft coupling limit.Comment: 6 pages, 9 figure
On the Unit Graph of a Noncommutative Ring
Let be a ring (not necessary commutative) with non-zero identity. The
unit graph of , denoted by , is a graph with elements of as its
vertices and two distinct vertices and are adjacent if and only if
is a unit element of . It was proved that if is a commutative ring
and \fm is a maximal ideal of such that |R/\fm|=2, then is a
complete bipartite graph if and only if (R, \fm) is a local ring. In this
paper we generalize this result by showing that if is a ring (not necessary
commutative), then is a complete -partite graph if and only if (R,
\fm) is a local ring and , for some or is a finite
field. Among other results we show that if is a left Artinian ring, and the clique number of is finite, then is a finite ring.Comment: 6 pages. To appear in Algebra Colloquiu
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