Underactive bladder - an underestimated entity

Introduction. The concept of underactive bladder is relatively new. Currently there is no generally accepted definition of this pathology. Diagnosis depends on urodynamic findings, and symptoms are usually rare and intricated with the symptoms of other urinary pathology. Matherials and methods. This review examines the current literature on underactive bladder regarding pathology, definition, diagnosis, current guidelines, and any further potential medical developments. Conclusions. Underactive bladder is a poorly understood pathologic condition. Only since 2002 has there been any consensus regarding the definition. The diagnosis relies only on urodynamics; clinical diagnosis is a challenge even for a consultant; and treatment does not seem to alleviate much of the suffering. This disease remains underrecognized and undertreated. More research is needed to identify less invasive diagnosis tools and treatment for this pathology

Unveiling the role of industries for European financial stability. Insights from the energy sector

Extensive analysis of intertwinement with other industries caused the energy sector to gain momentum in the recent economic literature. This paper aims to create an indicator that captures the impact of financial stability for energy companies on all other industrial groups. To this end, we use daily data from 2007 until the end of 2021 to compute financial stability metrics for all European companies from the STOXX 600 index. The main contribution of our study is to harness the neural network forecasting power to predict extreme levels of this impact. We motivate this choice with evidence from the literature that documents the improved performance of these methods in predicting crises. Our methodological approach also employs an outlier detection algorithm based on copula (COPOD) to identify situations when the energy sector substantially impacts other industries and develop a framework to predict out-of-sample situations. We found evidence that the Deep Renewal model has superior forecasting accuracy to the standard Croston model. The main conclusion is that the design of this methodological framework allows authorities to monitor the impact of shocks produced by the energy sector on financial stability at the European level and undertake strategic management actions

Studies Regarding Tailings Pond Seepage Water from Mining Activities over Avena sativa L. Germination Influence

Cultivation of oat in the limiting areas of tailings pond might be regarded as one of the possibilities that could lead to the general amelioration of these places. In order to characterize the waste products, to determine and evaluate the components that may be leached from waste products and that can affect the limiting areas of tailings pond, leaching tests were performed. In this paper, we have observed the influence of eluate, obtained from leaching tests, on seed germination, radicle and coleoptyle development as well as on the amount of accumulated dry matter for Avena sativa L., genotypes. According to our researches, we may conclude that the studied genotypes of Avena sativa L. showed tolerance to eluate while values registered for seed germination, radicle and coleoptyle development as well as dry matter content were comparatively higher than those registered for the control variant

Water Qualitative Parameters of Fluviatile Limans Located in the South - West of Dobrogea (Romania)

The fluviatile limans in the south-west of Dobrogea are the most characteristic forms of this type, with an exclusive development on the territory of Romania. In time, they were interpreted as fluvio-maritime limans or even as fluvio-lacustrine limans. As a result of the fact that they are situated close to the Danube, bordering one of the driest regions of Romania, they have had diverse usage since ancient times. Because the fluviatile limans in Dobrogea are mostly used in pisciculture, the water qualitative parameters have to be monitored permanently. They also have a role in attenuating floods, acting as a tampon against flash floods. Consequently, they have a special local importance even today, feeding as much of the population as possible (directly or indirectly). From a geomorphological point of view the fluviatile limans in Dobogea were formed as a result of the withdrawal of the Romanian (Levantine). The decrease in depth may cause the flood waves to pass over the dams. In this case, the periodical drainage of lake cuvettes is required. The physical parameters of water (depth, transparency and temperature) as well as the chemical parameters (pH, dissolved oxygen, nitrates, nitrites, phosphates and the Ca/Mg ratio) have been analyzed. From an ecological viewpoint, the fluviatile limans in the south-west of Dobrogea are suitable for fish breeding and for developing an adequate lacustrine life

Data-Driven Model-Free Sliding Mode and Fuzzy Control with Experimental Validation

The paper presents the combination of the model-free control technique with two popular nonlinear control techniques, sliding mode control and fuzzy control. Two data-driven model-free sliding mode control structures and one data-driven model-free fuzzy control structure are given. The data-driven model-free sliding mode control structures are built upon a model-free intelligent Proportional-Integral (iPI) control system structure, where an augmented control signal is inserted in the iPI control law to deal with the error dynamics in terms of sliding mode control. The data-driven model-free fuzzy control structure is developed by fuzzifying the PI component of the continuous-time iPI control law. The design approaches of the data-driven model-free control algorithms are offered. The data-driven model-free control algorithms are validated as controllers by real-time experiments conducted on 3D crane system laboratory equipment

Underactive bladder - an underestimated entity

Introduction. The concept of underactive bladder is relatively new. Currently there is no generally accepted definition of this pathology. Diagnosis depends on urodynamic findings, and symptoms are usually rare and intricated with the symptoms of other urinary pathology. Matherials and methods. This review examines the current literature on underactive bladder regarding pathology, definition, diagnosis, current guidelines, and any further potential medical developments. Conclusions. Underactive bladder is a poorly understood pathologic condition. Only since 2002 has there been any consensus regarding the definition. The diagnosis relies only on urodynamics; clinical diagnosis is a challenge even for a consultant; and treatment does not seem to alleviate much of the suffering. This disease remains underrecognized and undertreated. More research is needed to identify less invasive diagnosis tools and treatment for this pathology

A LOW-COST APPROACH TO DATA-DRIVEN FUZZY CONTROL OF SERVO SYSTEMS

Servo systems become more and more important in control systems applications in various fields as both separate control systems and actuators. Ensuring very good control system performance using few information on the servo system model (viewed as a controlled process) is a challenging task. Starting with authors’ results on data-driven model-free control, fuzzy control and the indirect model-free tuning of fuzzy controllers, this paper suggests a low-cost approach to the data-driven fuzzy control of servo systems. The data-driven fuzzy control approach consists of six steps: (i) open-loop data-driven system identification to produce the process model from input-output data expressed as the system step response, (ii) Proportional-Integral (PI) controller tuning using the Extended Symmetrical Optimum (ESO) method, (iii) PI controller parameters mapping onto parameters of Takagi-Sugeno PI-fuzzy controller in terms of the modal equivalence principle, (iv) closed-loop data-driven system identification, (v) PI controller tuning using the ESO method, (vi) PI controller parameters mapping onto parameters of Takagi-Sugeno PI-fuzzy controller. The steps (iv), (v) and (vi) are optional. The approach is applied to the position control of a nonlinear servo system. The experimental results obtained on laboratory equipment validate the approach

Performance Improvement of Low-Cost Iterative Learning-Based Fuzzy Control Systems for Tower Crane Systems

This paper is dedicated to the memory of Prof. Ioan Dzitac, one of the fathers of this journal and its founding Editor-in-Chief till 2021. The paper addresses the performance improvement of three Single Input-Single Output (SISO) fuzzy control systems that control separately the positions of interest of tower crane systems, namely the cart position, the arm angular position and the payload position. Three separate low-cost SISO fuzzy controllers are employed in terms of first order discrete-time intelligent Proportional-Integral (PI) controllers with Takagi-Sugeno-Kang Proportional-Derivative (PD) fuzzy terms. Iterative Learning Control (ILC) system structures with PD learning functions are involved in the current iteration SISO ILC structures. Optimization problems are defined in order to tune the parameters of the learning functions. The objective functions are defined as the sums of squared control errors, and they are solved in the iteration domain using the recent metaheuristic Slime Mould Algorithm (SMA). The experimental results prove the performance improvement of the SISO control systems after ten iterations of SMA

Colorectal Cancer and Inflammatory Bowel Disease

Inflammatory bowel disease (IBD) with its two entities, ulcerative colitis and Crohn’s disease, is at increased risk of developing colorectal cancer (CRC). Risk factors for CRC are represented by the duration of the disease, extent of disease, the association of primary sclerosing cholangitis, family history, and early age at onset. In inflammatory bowel disease, colonic carcinogenesis appears on an inflamed colon, being determined by different genetic alterations. The main element of the process of carcinogenesis is the dysplasia, which is a neoplastic intraepithelial transformation, limited to the basal membrane surrounding the glands around which it appears. The stages of carcinogenesis process start with dysplasia of varying degrees as follows: indefinite dysplasia, low-grade dysplasia, high-grade dysplasia, and finally invasive adenocarcinoma