Precision Measurement of the Longitudinal Double-Spin Asymmetry for Inclusive Jet Production in Polarized Proton Collisions at s√=200 GeV

We report a new measurement of the midrapidity inclusive jet longitudinal double-spin asymmetry, ALL, in polarized pp collisions at center-of-mass energy s√=200  GeV. The STAR data place stringent constraints on polarized parton distribution functions extracted at next-to-leading order from global analyses of inclusive deep-inelastic scattering (DIS), semi-inclusive DIS, and RHIC pp data. The measured asymmetries provide evidence at the 3σ level for positive gluon polarization in the Bjorken-x region x\u3e0.05

Human psychophysiological responses to visceral and somatic pain – the development of integrated, reproducible human pain phenotypes

PhDBackground Pain is the ubiquitous human experience, yet displays considerable inter- and intraindividual variability in health and disease. Many factors have been proposed to account for these differences. Pain activates a complex stress response, multiply determined through genetic, psychological, physiological and neuroanatomical factors. Chronic pain is a central defining characteristic of functional gastrointestinal disorders. They represent a major challenge for modern healthcare. An integrated understanding of the pathophysiology of these disorders remains to be elucidated. Aims To investigate human psychophysiological responses to visceral and somatic pain in health and disease, in order to develop multidimensional and reproducible pain phenotypes. Methods Study 1, in healthy volunteers, investigated personality traits, hypothalamic pituitary adrenal axes and selective novel non-invasive measures of autonomic tone in response to visceral and somatic pain. Study 2 examined the salience of genetic polymorphisms of the serotonin transporter. Study 3 evaluated the reproducibility of these responses after a period of one year. Study 4 utilised the methods of studies 1 and 2 in a case control study of patients with functional chest pain. Key Results Studies 1, 2 and 3 – Two pain phenotypes, or clusters, were found – cluster 1 (39%) had higher neuroticism scores, with higher sympathetic and hypothalamic pituitary adrenal axis tone at rest, and a predominant parasympathetic response to pain in the presence of the short allele of the serotonin transporter. Cluster 2 (61%) displayed the converse profile in the absence of the short allele. These responses were stable at an interval of one year. Study 4 – similar phenotypes were observed in patients with functional chest pain, although the Cluster 1 phenotype was overrepresented in patients in comparison to the controls (71% vs. 29%). Conclusions and Inferences This series of studies provides evidence for the existence of two reproducible human pain phenotypes in health, which have clinical salience in patients with functional chest pain. By phenotyping pain responses, subject homogeneity in future studies may be improved. Furthermore, such phenotyping techniques may open new therapeutic avenues by facilitating the selective targeting of nociceptive aberrancies, particularly in functional gastrointestinal disorders

Terminal Station: The Creation And Study of A Canadian Rock Operetta (And Its Idiomatic Soup)

What does the action or discipline of composition mean in 2017? Different arts will flow into, and away from each other organically. Rigidly defined boundaries can restrict what art belongs where, and which preservation and qualitative techniques are used, and can be an impediment to evolving the creative process. Authenticity happens in a fleeting moment; it is a product of an evolving environment; some aspects natural, others arranged and ordered. It may be fortuitous to freeze creation in a moment, and it may not. Preserving compositions made using the digital Audio Workstation will require acceptance of methods that are not yet standard pedagogy, but are common and required in the business and professional lives of composers all over the world. The process used to create of the original Rock Operetta Terminal Station, initiates a discussion about method, content and technology, and supports a philosophical and cosmopolitan compositional environment in 2017

Obtaining High Precision Results from Low Precision Hardware

This document describes an attempt at acheiving high precision matrix multiplication results from the Lenslet EnLight256 Optical Signal Processor (OSP), which on its own can only produce results which are hardware limited to 8-bit signed integers. Due to it’s low precision, it’s has only limited applicability to real world problems, and if higher precision results were possible from the machine it could be used for more applications. A C library is developed for this thesis to allow high-precision results from the EnLight256. The library is described and results are given. Finally an implementation of the Jacobi Method on the EnLight256 is given as an example of the library being used in a real world scenario

Measurement of D0 Azimuthal Anisotropy at Midrapidity in Au + Au Collisions at √ s N N = 200 GeV

We report the first measurement of the elliptic anisotropy (v2) of the charm meson D0 at midrapidity (|y