La rhodophycée Gelidium spinosum (S.G. Gmelin) P.C. Silva, des côtes de Monastir (Tunisie) : quelques éléments hydrobiologiques et potentialités en agar-agar

La rhodophycée Gelidium spinosum (S.G. Gmelin) P.C. Silva (Rhodophycées ; Gélidiales) a été étudiée pendant une année, depuis septembre 2000 jusqu’à août 2001, sur la côte de Monastir (Est de la Tunisie). Les résultats globaux obtenus montrent que le poids humide maximum (environ 37 g/individu) a été atteint en mai. La longueur maximale (environ 11 cm) a été enregistrée en juin. La biomasse maximale en poids humide (environ 7000 g/m2) a été obtenue en mai. Quant à la fertilité, elle a varié entre 0%(Mai) et 100% (Septembre, Juin, Juillet et Août). Concernant le rendement en agar, le maximum a été obtenu en avril (33.4 % du poids sec), La force de gel maximale a atteint environ 705 g.cm-² (juin). Le point de gélification et le point de fusion les plus élevés ont été obtenus respectivement en août (34.33°C) et septembre (94.33°C).Mots-clés : Gelidium spinosum, poids, longueur, biomasse, fertilité, agar-agar

Case Report - Métastase splénique d’un adénocarcinome colique - à propos d’un cas et revue de la littérature

L'atteinte métastatique de la rate est rare et exceptionnellement isolée. En effet, elle survient généralement dans le cadre d'une atteinte multi viscérale. Les cancers les plus pourvoyeurs de métastase splénique sont les mélanomes, les carcinomes de l'ovaire, du sein et du poumon. Dans le cancer colique, l'atteinte métastatique isolée de la rate est rare, dix cas seulement ont été décrits dans la littérature jusque-là. À travers cette revue, nous décrivons un nouveau cas présentant un adénocarcinome colique avec métastase splénique métachrone, tout en discutant les aspects cliniques et les différentes approches thérapeutiques décrites dans la littérature. Nous rapportons un nouveau cas d’un patient âgé de 46ans ayant un adénocarcinome colique traité, et qui a présenté 5 ans plus tard une métastase splénique de découverte fortuite lors d’un bilan radiologique de surveillance, pour laquelle le patient a bénéficié d’une splénectomie suivie d’une chimiothérapie systémique avec une bonne évolution. Les métastases spléniques isolées des tumeurs solides sont rares, et leur diagnostic est souvent de découverte fortuite. La splénectomie totale est un moyen efficace de faire le diagnostic définitif de ces métastases et de les traiter afin de prévenir les complications et d’améliorer la survie

Genetic Structure and Connectivity of the Red Mangrove at Different Geographic Scales through a Complex Transverse Hydrological System from Freshwater to Marine Ecosystems

Mangrove forests are ecologically and economically valuable resources composed of trees morphologically and physiologically adapted to thrive across a range of habitats. Although, mangrove trees have high dispersion capacity, complexity of hydrological systems may lead to a fine-scale genetic structure (FSGS). The Transverse Coastal Corridor (TCC) is an interesting case of hydrological systems from fresh to marine waters where mangrove forests dominate. We evaluated genetic diversity and structure of Rhizophora mangle across a range of hydrological conditions within the TCC using inter-simple sequence repeat molecular markers. Sampling included four hydrological systems, two localities inside each system, and fringe and dwarf trees. Genetic differentiation was evaluated at local (<100 km) and fine (<10 km) scales through a set of analyses, and genetic diversity was evaluated at all scale levels and between fringe and dwarf physiognomic types. Rhizophora mangle exhibited a high genetic structure at both scales with high genetic diversity. The genetic structure observed among hydrological systems likely reflects the historical dispersion of mangroves, whereas the FSGS reflect contemporary processes such as seed dispersal restriction, habitat fragmentation, and local water flow regimes. A higher genetic diversity for dwarf than for fringe trees and differentiation between both physiognomic types at a fine-scale were observed and discussed

Flood Control: How Milk-Derived Extracellular Vesicles Can Help to Improve the Intestinal Barrier Function and Break the Gut–Joint Axis in Rheumatoid Arthritis

Many studies provided compelling evidence that extracellular vesicles (EVs) are involved in the regulation of the immune response, acting as both enhancers and dampeners of the immune system, depending on the source and type of vesicle. Research, including ours, has shown anti-inflammatory effects of milk-derived EVs, using human breast milk as well as bovine colostrum and store-bought pasteurized cow milk, in !##!Review criteria!#!The search terms 'extracellular vesicles', 'exosomes', 'microvesicles', 'rheumatoid arthritis', 'gut-joint axis', 'milk', and 'experimental arthritis' were used. English-language full text papers (published between 1980 and 2021) were identified from PubMed and Google Scholar databases. The reference list for each paper was further searched to identify additional relevant articles

Similar prevalence of expanded CGG repeat lengths in the fragile X mental retardation I gene among infertile women and among women with proven fertility : a prospective study

Purpose:We sought to determine the usefulness of fragile X mental retardation 1 (FMR1) carrier testing among young infertile women with or without signs of ovarian insufficiency as compared with fertile women.Methods:Three cohorts of women were recruited to determine the cytosine-guanine-guanine (CGG) repeats trinucleotide repeat length in the 5'-untranslated region of the FMR1 gene in lymphocyte DNA. A total of 199 fertile women, who were reported to have conceived within 3 months, were recruited together with 372 infertile women with ongoing menstrual cycles and 48 infertile women with primary ovarian insufficiency. The various ranges of FMR1 CGG repeat lengths among infertile women were compared with those of fertile controls. In infertile women with ongoing menstrual cycles, the serum concentrations of follicle-stimulating hormone, anti-Muellerian hormone, and inhibin B were measured during the early follicular phase.Results:None of the three categories of FMR1 CGG repeat length expansions (premutation, intermediate range, and high normal range) were more prevalent among infertile women than among fertile women. The CGG repeat length was not correlated with any of the ovarian reserve parameters.Conclusion:In comparison with a generalized preconception screening strategy, infertility as a criterion, even together with reduced ovarian reserve, is not suitable for identifying a higher proportion of women with expanded FMR1 CGG repeat length.Genet Med advance online publication 10 October 2013Genetics in Medicine (2013); doi:10.1038/gim.2013.146