Nanoanalysis of a sub-nanometre reaction layer in a metal inserted high-k gate stack

Reactions at the interfaces can occur in metal inserted high-k gate stacks and are likely to evolve during device processing. Such reactions may affect the electrical properties of the stack and hence these could change during processing. The key interfaces are often not atomically flat and characterising the reaction layers on the near atomic scale required is a challenge. Aberration corrected scanning transmission electron microscopy (STEM) and spectrum imaging (SI) using electron energy loss spectroscopy (EELS) is used to characterise an HfN or Hf(O,N) reaction layer, ∼0.25 nm wide, between HfO<sub>2</sub> and TiN. This demonstrates the very significant advances in high spatial resolution characterisation made in recent years

Magnetic induction plasma engine Final report

Wall interaction reduction in magnetic induction plasma accelerato

Feasibility of Photofrin II as a radiosensitizing agent in solid tumors - Preliminary results

Background: Photofrin II has been demonstrated to serve as a specific and selective radiosensitizing agent in in vitro and in vivo tumor models. We aimed to investigate the feasibility of a clinical application of Photofrin II. Material and Methods: 12 patients were included in the study (7 unresectable solid tumors of the pelvic region, 3 malignant gliomas, 1 recurrent oropharyngeal cancer, 1 recurrent adenocarcinoma of the sphenoid sinus). The dose of ionizing irradiation was 30-50.4 Gy; a boost irradiation of 14 Gy was added for the pelvic region. All patients were intravenously injected with 1 mg/kg Photofrin II 24 h prior to the commencement of radiotherapy. Magnetic resonance imaging (MRI) controls and in some cases positron emission tomography (PET) were performed in short intervals. The mean follow-up was 12.9 months. Results: No major adverse events were noted. Minor adverse events consisted of mild diarrhea, nausea and skin reactions. A complete remission was observed in 4/12 patients. A reduction in local tumor volume of > 45% was achieved in 4/12 patients. Stable disease was observed in 4/12 patients. 1 patient showed local disease progression after 5 months. Conclusion: The early follow-up results are encouraging regarding the feasibility of the application of Photofrin II as a radiosensitizing agent

Monopile Foundation Offshore Wind Turbine Simulation and Retrofitting

Offshore wind turbines (OWT) provide a renewable source of energy with great proximity to many large cities. This has caused a major increase in OWT development and implementation, primarily in Europe, but spreading throughout the world. There are a multitude of different foundation options, each with their own benefits. The most common types are: monopile, jacket, TLP, Semi-Submersible, and SPAR. The monopile foundation OWT has been proven to be the most economic selection for water depths up to approximately 25m. This thesis has analyzed strictly monopile foundations due to their previous success and popularity. Three different chapters have been created to cover the two different research papers contained in this thesis. Chapter one utilizes the software ANSYS to complete a multi-hazard computational fluid dynamic (CFD) analysis of a monopile foundation OWT. A dynamic analysis was performed on the structure, with a p-y curve soil-structure interaction implemented. Chapter two aims to verify the plausibility of a retrofit solution to a significant problem certain previously installed monopiles have developed. The annulus grout of the transition zone of the structure has been determined to be under-designed, and thus has experienced crushing. This allows the tower to slightly slide down the monopile, increasing the chances of total structural failure. A retrofit bolted connected has been implemented, and proven to significantly increase the limiting shear capacity of the structure. The research paper in chapter three is focused on developing the retrofit solution into a more applicable design. Using a response surface methodology (RSM) an optimized design criteria has been generated based on six geometric/material parameters of the bolted connection: horizontal spacing, vertical spacing, bolt diameter, number of bolts in vertical columns, pre-tensioning load on bolt, and modulus of elasticity