31 research outputs found
Evaluating the clonal hierarchy in light-chain multiple myeloma: implications against the myeloma stem cell hypothesis
No full textAn exclusive production of light chains can be found in ~15% of myeloma cases, and in these light-chain multiple myeloma (LC-MM) cases, the phenotype remains unchanged throughout subsequent progression and relapse. Once established, it suggests that this phenotype is maintained by the ‘feeder cell’ that re-populates the tumor bulk as disease re-emerges<br/
Acoustic Feature Analysis and Discriminative Modeling of Filled Pauses for Spontaneous Speech Recognition
No full textInsertional events as well as translocations may arise during aberrant immunoglobulin switch recombination in a patient with multple myeloma
No full textDiverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma
No full textInsertional events as well as translocations may arise during aberrant immunoglobulin switch recombination in a patient with multiple myeloma
No full textDetection of illegitimate rearrangements within the immunoglobulin light chain loci in B cell malignancies using end sequenced probes
No full textThe Pathogenetic Role of Oncogenes Deregulated by Chromosomal Translocation in B-Cell Malignancies
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