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    ๊ฐ€๊ฒฉ ๊ฒฝ์ง์„ฑ๊ณผ ์‚ฌํšŒํ›„์ƒ

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    ๋ณธ๊ณ ๋Š” ์‹ ์ถ•์  ๊ฐ€๊ฒฉํ•˜์—์„œ์˜ ๊ฒฝ์ œ, ์ฆ‰ ์ธํ”Œ๋ ˆ์ด์…˜์ด ์™œ๊ณก์„ ์œ ๋ฐœํ•˜์ง€ ์•Š๊ณ  ์ด์ƒ์‚ฐ์ด ํ•ญ์ƒ ์ž์—ฐ์‚ฐ์ถœ๋Ÿ‰ ์ˆ˜์ค€์„ ๋‹ฌ์„ฑํ•˜๋Š” ๊ฒฝ์ œ๊ฐ€ ๊ณผ์—ฐ ๊ฒฝ์ง์  ๊ฐ€๊ฒฉํ•˜์—์„œ์˜ ๊ฒฝ์ œ๋ณด๋‹ค ์‚ฌํšŒํ›„์ƒ์ธก๋ฉด์—์„œ ํ•ญ์ƒ ๋” ๋ฐ”๋žŒ์งํ•œ์ง€์— ๋Œ€ํ•ด ๋…ผ์˜ํ•œ๋‹ค. ํŠนํžˆ ๊ธˆ์œต์‹œ์žฅ์ด ๋ถˆ์™„์ „ํ•˜๊ณ ,๋ถ€๋ฌธ ๊ฐ„ ๋ช…๋ชฉ ๊ฒฝ์ง๋„๊ฐ€ ์œ ์˜ํ•˜๊ฒŒ ๋‹ค๋ฅด๋ฉฐ, ์‚ฌํšŒํ›„์ƒ ์ตœ๋Œ€ํ™”๋ฅผ ๋ชฉ์ ์œผ๋กœ ํ†ตํ™”์ •์ฑ…์ด ์šด์˜๋˜๋Š” ๊ฒฝ์šฐ, ๊ฒฝ์ง์  ๊ฐ€๊ฒฉ์ด ๊ฐ€๊ณ„ ํ›„์ƒ์— ๋” ์œ ๋ฆฌํ•˜๋‹ค๋Š” ์ ์„ ๋ฐํžŒ๋‹ค. ๋ถˆ์™„์ „ ๊ธˆ์œต์‹œ์žฅ์€ ์†Œ๋น„์™€ ์ƒ์‚ฐ์˜ ๋น„ํšจ์œจ์ ์ธ ๋ฐฐ๋ถ„์„ ์ดˆ๋ž˜ํ•œ๋‹ค. ํ†ตํ™”์ •์ฑ…์€ ๋ช…๋ชฉ ๊ฒฝ์ง์„ฑ ๋ฐ ๋ถˆ์™„์ „๊ธˆ์œต์‹œ์žฅ์œผ๋กœ ์ธํ•œ ํ›„์ƒ์†์‹ค์„ ์™„ํ™”ํ•  ์ˆ˜ ์žˆ์œผ๋‚˜, ์ด๋Š” ๊ฒฝ์ง์  ๊ฐ€๊ฒฉํ•˜์—์„œ์˜ ๊ฒฝ์ œ์— ์„œ๋งŒ ์œ ํšจํ•˜๋‹ค

    (The) mechanical, physical and biological safety study of dense calcium phosphate ceramics for the application of dental implant

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    ์น˜์˜ํ•™๊ณผ/๋ฐ•์‚ฌ[ํ•œ๊ธ€] ์ธ์ฒด๋‚ด์˜ ๊ณจ์กฐ์ง๊ณผ ์น˜์•„์˜ ์„ฑ๋ถ„์— ๊ฐ€์žฅ ๊ฐ€๊น๊ณ  ๊ณจ์กฐ์ง๊ณผ ์—ฐ์กฐ์ง๊ฐ„์˜ ์นœํ™”๋ ฅ์ด ์šฐ์ˆ˜ํ•œ ์ƒ๋ฌผํ•™์ ์ธ ์น˜๊ณผ์ด์‹ ์žฌ๋ฃŒ๋กœ์จ ์ตœ๊ทผ์— ๋งŽ์€ ๊ด€์‹ฌ์„ ๊ฐ–๊ณ  ์‘์šฉ๋˜๋Š” Calcium phosphate๋ฅผ Isostatic press๋ฅผ ์ด์šฉํ•œ ์†Œ๊ฒฐ๋ฒ•์œผ๋กœ 1000โ„ƒ, 1100โ„ƒ, 1200โ„ƒ์˜ ์˜จ๋„์—์„œ ๊ฐ๊ฐ ์†Œ๊ฒฐํ•œ ํ›„ Vitallium ์นจ๋ด‰์„ ์ ‘์ฐฉ์‹œํ‚จ ์›์ฃผํ˜•์˜ ์‹œํŽธ์„ ์ œ์ž‘ํ•˜์—ฌ ๊ธฐ๊ณต์œจ, ๋ถ€ํ”ผ๋น„์ค‘, ์ƒ๋Œ€๋น„์ค‘, X-์„  ํšŒ์ ˆ๋ถ„์„, ์••์ถ•๊ฐ•๋„, ์ „๋‹จ๊ฐ•๋„, ๋ฏธ์„ธ๊ฐ•๋„, ์ „์žํ˜„๋ฏธ๊ฒฝ ์†Œ๊ฒฌ๋“ฑ์˜ ๊ธฐ๊ณ„์ , ๋ฌผ๋ฆฌ์  ์„ฑ์งˆ๊ณผ HeLa ์„ธํฌ๋ฅผ ์ด์šฉํ•œ ์กฐ์ง๋ฐฐ์–‘๋ฒ•์œผ๋กœ ์ƒ๋ฌผํ•™์ ์•ˆ์ „์„ฑ์„ ๊ด€์ฐฐํ•˜์—ฌ์„œ ๋‹ค์Œ๊ณผ ๊ฐ™์€ ๊ฒฐ๋ก ์„ ์–ป์—ˆ๋‹ค. 1. 1200โ„ƒ์—์„œ ์†Œ๊ฒฐํ•œ tricalcium phosphate ceramics๋Š” ๋‹ค๋ฅธ ์˜จ๋„์—์„œ๋ณด๋‹ค ๋†’์€ ๊ธฐ๊ณ„์  ๊ฐ•๋„๋ฅผ ๋‚˜ํƒ€๋‚ด์—ˆ๋‹ค. 2. ์†Œ๊ฒฐ์˜จ๋„๊ฐ€ ์ƒ์Šนํ•จ์— ๋”ฐ๋ผ ์ „์ฒด์ ์ธ ๊ธฐ๊ณต์œจ์€ ๊ฐ์†Œํ•˜๋‚˜ ๋ฐ˜๋Œ€๋กœ ๊ธฐ๊ณต์˜ ํฌ๊ธฐ๋Š” ํฌ๊ฒŒ ๋‚˜ํƒ€๋‚ฌ๋‹ค. 3. 1200โ„ƒ์—์„œ ์†Œ๊ฒฐํ•œ tricalcium Phosphate ceramics์˜ ์ƒ๋Œ€๋ฐ€๋„๋Š” 96.65%๋กœ์จ ๋‹ค๋ฅธ ์˜จ๋„์—์„œ๋ณด๋‹ค ๋†’๊ฒŒ ๋‚˜ํƒ€๋‚ฌ๋‹ค. 4. Tricalcium phosphate๋ฅผ 1000โ„ƒโˆผ1200โ„ƒ ๋ฒ”์œ„์—์„œ ์†Œ๊ฒฐํ•œ ๊ฒฝ์šฐ ๋ชจ๋‘ ฮฒ-whitlockite๋กœ ์ƒ๋ณ€ํƒœ ํ•˜์˜€๋‹ค. 5. Triealcium phosphate ceramics๋Š” ์†Œ๊ฒฐ์˜จ๋„์— ์ƒ๊ด€์—†์ด ๋ชจ๋‘ vitallium๊ณผํ•จ๊ป˜ ์ƒ๋ฌผํ•™์ ์ธ ์•ˆ์ „์„ฑ์„ ๋ณด์˜€๋‹ค. [์˜๋ฌธ] The calcium phosphate ceramics are bioactive materials for dental implant that resembles those of dental enamel, dentin and bone, which forming tight bond resembles ankylosis with surrounding bone and soft tissue. Dense calcium phosphate ceramics were made of commercially available tricalcium phosphate salts by compression and subsequent sintering at each temperature 1000โ„ƒ, 1100โ„ƒ and 1200โ„ƒ. Subsequently artificial teeth were made of cylindrical form that consist of a vitallium rod for post & core and a surface of sintered dense calcium phosphate ceramics for interfacing with alveolar bone. In this experimental study, mechanical and physical properties of sintered calcium phosphate ceramics were obtained from measurement of bulk density, relative density, apparent porosity, compressive strength, modulus of rupture strength, vickers hardness, average pore and grain size. The biological safety of these materials was tested from the tissue culture method using HeLa Cells. The results of this study were obtained as follows; 1. Tricalcium phosphate ceramics sintered at temperature 1200โ„ƒ exhibited better mechanical strengths. 2. As much as sintering temperature arised, apparent porosity was reduced, but avarage pore size was larged. 3. The relative density of tricalcium phosphate ceramics sintered at 1200โ„ƒ was 96.65%. 4. When tricalcium phosphate salts sintered at temperature between 1000โ„ƒ and 1200โ„ƒ, they were transformed to ฮฒ-whitlockite. 5. Tricalcium phosphate ceramics exhibited biological safety regardless of sintering temperature.restrictio

    (An) Experimental histopathologic study of the tissue reaction to non-precious alloys which implanted in and contacted on the oral mucosa

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    ์น˜์˜ํ•™๊ณผ/์„์‚ฌ[ํ•œ๊ธ€]์น˜๊ณผ์šฉ ๋น„๊ท€๊ธˆ์† ํ•ฉ๊ธˆ์˜ ์ž„์ƒ์—์„œ์˜ ์„ฑ๊ณต์ ์ธ ์‚ฌ์šฉ์„ ์œ„ํ•ด์„œ๋Š” ์ข‹์€ ๋ฌผ๋ฆฌ์  ์„ฑ์งˆ๋ฟ๋งŒ ์•„๋‹ˆ๋ผ, ์กฐ์ง๊ณผ์˜ ์นœํ™”์ƒ๋„ ์ข‹์•„์•ผ ํ•  ๊ฒƒ์ด๋‹ค. ์ €์ž๋Š” ์ด๋Ÿฌํ•œ ์น˜๊ณผ์šฉ ๋ณด์ฒ ๋ฌผ ์ œ์ž‘์— Tm์ด๋Š” ์ˆ˜์ข…๋น„๊ท€๊ธˆ์† ํ•ฉ๊ธˆ์ด ๊ตฌ๊ฐ•์ ๋ง‰์— ๋ฏธ์น˜๋Š” ์ƒ์ฒด๋ฐ˜์‘์— ๊ด€ํ•œ ๋ณ‘๋ฆฌ์กฐ์งํ•™์  ๊ด€์ฐฐ์„ ํ•˜๊ธฐ ์œ„ํ•˜์—ฌ,Ni-Crํ•ฉ๊ธˆ๊ณ„, Ag-Pdํ•ฉ๊ธˆ๊ณ„, ๊ทธ๋ฆฌ๊ณ , ์ œ 3ํ˜• ์ฃผ์กฐ๊ธˆ์œผ๋กœ ๊ธˆ์†ํŽธ์„ ์ œ์ž‘ํ•˜์—ฌ ํ•œ๊ตญ์‚ฐ ์žฌ๋ž˜์ข… ์„ฑ๊ฒฌ 2๋งˆ๋ฆฌ์˜ ๊ตฌ๊ฐ•์ ๋ง‰ํ•˜์— ๋งค์‹ํ›„ 10์ผ, 30์ธ, 60์ผ ๊ฐ„๊ฒฉ์œผ๋กœ, ์—ฐ๊ฒฐ๊ณ ์ • ๊ธˆ๊ด€์„ ์ด์šฉํ•˜์—ฌ, ๊ธˆ์†ํŽธ์„ ๊ตฌ๊ฐ•์ ๋ง‰์— ์ ‘์ด‰ํ•œ ํ›„ 30์ผ, 60์ผ ๊ฐ„๊ฒฉ์œผ๋กœ ์กฐ์ง๋ฐ˜์‘์„ ๊ด€์ฐฐํ•œ ๊ฒฐ๊ณผ ๋‹ค์Œ๊ณผ ๊ฐ™์€ ๊ฒฐ๋ก ์„ ์–ป์—ˆ๋‹ค. 1. ๊ตฌ๊ฐ•์ ๋ง‰ํ•˜ ๋งค์‹๊ตฐ 10์ผ์—์„œ๋Š” ๊ธ‰๋งŒ์„ฑ ์—ผ์ฆ์„ธํฌ์˜ ์นจ์œค๊ณผ ์„ฌ์œ ์•„์„ธํฌ์˜ ์ฆ์‹์ƒ์„ ๋ณด์˜€๊ณ , 30์ผ ์ดํ›„์—๋Š” ์ด๋ฌผ์งˆ๋กœ ์ธํ•œ ๋งŒ์„ฑ์œก์•„์ข… ์—ผ์ฆ์†Œ๊ฒฌ์„ ๋ณผ ์ˆ˜ ์žˆ์—ˆ๋‹ค. 2. ๊ตฌ๊ฐ•์ ๋ง‰์— ์ ‘์ด‰๊ตฐ์—์„œ๋Š” ๊ธ‰๋งŒ์„ฑ ์—ผ์ฆ์„ธํฌ์˜ ์นจ์œค์„ ๋ณด์˜€์œผ๋ฉฐ, ์ƒํ”ผ์„ธํฌ์˜ ๊ทน์„ธํฌ์ฆ๊ณผ ๊ตญ์†Œ์ ์œผ๋กœ ๊ถค์–‘์ด ํ˜•์„ฑ๋œ ๊ฒƒ์„ ๊ด€์ฐฐํ•˜์˜€๋‹ค. 3. ๊ตฌ๊ฐ•์ ๋ง‰์— ์ฒฉ์ด‰๊ตฐ์—์„œ๋Š” ๋งค์‹๊ตฐ์—์„œ ๋ณด์—ฌ์ฃผ๋Š” ์ƒ์ฒด์˜ ๋ฐฉ์–ด๊ธฐ์ „์ธ ์„ฌ์œ ํ™”๋ฅผ ๋ณผ ์ˆ˜ ์—†์—ˆ๋‹ค. 4. ๊ตฌ๊ฐ•์ ๋ง‰ํ•˜ ๋งค์‹๊ตฐ์—์„œ WASHI A-LOY๋Š” ๋‹ค๋ฅธ ๊ธˆ์†์— ๋น„ํ•ด ๋น„๊ต์  ๊ฒฝ๋ฏธํ•œ ์—ผ์ฆ๋ฐ˜์‘์„ ๋ณด์˜€์œผ๋ฉฐ, Rexillium โ…ข๋Š” ๊ฐ€์žฅ ์‹ฌํ•œ ์—ผ์ฆ๋ฐ˜์‘์„ ๋ณด์˜€๋‹ค. 5. ๊ตฌ๊ฐ•์ ๋ง‰์— ์ ‘์ด‰๊ตฐ์—์„œ๋Š” Ag-Pdํ•ฉ๊ธˆ์ด Ni-Crํ•ฉ๊ธˆ๋ณด๋‹ค ์กฐ์ง์†์ƒ์ด ์ ์€ ๊ฒƒ์„ ๊ด€์ฐฐํ•˜์˜€๋‹ค. [์˜๋ฌธ]This study was undertaken to observe the histopathalogic reaction to non-precious alloys when the alloys were implanted in and contacted on the oral mucosa The alloys used were Nickel Chromo alleys, Silver Palladium alloys and Casting gold โ…ข tyre alloys. Two dogs of the experiment were decided into implanted and contacted groups. Experiment groups were serially performed under a general anesthesia using Secobarbital Sodium at the fellowing postimplantation time intervals: 10, 30, and 60 days and postcontact time intervals: 30 and 60 days. Under anesthesia, the oral mucosa was dissected out and stained wish Hematoxylin and Eosin. After examination and comparision of all specimens, the results of this study were obtained as follows. 1. In the after 10th days implantation, acute and chronic inflammatory cells were infiltrated ,and fibroblasts were proliferated. After 30th days, chronic granulomatous inflammation as a foreign body reactions was present. 2. The reaction to contacted group, the acanthosis of the epithelial cells and the formation of the localized ulcerations were observed, and acute and chronic inflammatory cells were infiltrated. 3. The contacted group did not show fibrosis considered as a defence mechanism of the host which was seen in implanted group. 4. The reaction to implanted group, WASHI A-LOY showed more mild inflammatory reaction than any other alleys but Rexillium โ…ข showed the most severe inflammatory reaction. 5. The reaction to contacted group, Silver Palladium alloys induced less tissue damage than Nickel Chrome alloys.restrictio

    Enhancement of Signal Reliability through Optimizing Contact Condition of CLECDiS

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    MasterNanotechnology is said to include varieties of technological researchs such as new fabrication technologies to modeling tools for nano-scale physical phenomena. Among them the utra-precision positioning systems may be one of the main technologies for realizing experimental toolds for nanotechnology. It is also a key technology for fabrication of devices with nano-scale size components in the current industries.In order for upgrading the positioning technology, long-range displacement sensors with ultra-precision might be inevitable because the repeatability of a positioning system usually relies on the displacement sensor adopted in it. The Contact-type Linear Encorder-Like Capacitive Displacement Sensor (CLECDiS) has been developed for this purpose: to provide a compact low-cost urtra-precision long-range displacement sensor.Evern though the resolution of 0.35nm have been proved to be achieved based on the SNR(Signal-to-Noise Ratio) of its detection cuircuitry, it is required to develop the methods to implement the CLECDiS into a positioning system in order to use it stably as the displacement sensor of a system. In this study, the contact conditions of the two facing electrodes of CLECDiS and their effects are evaluated and the methods are proposed and tested to improve their contact conditions. Basically the supporting jigs and stages are redesigned to improbe the contact conditions and the testing results show that improvement in the contact condtions may considerably stabilize the output signals from CLECDiS.In this thesis, as a part of researches on improment of the contact conditions, the repeatability of the output signals is improved about 28 times of the signals obtained from the previous samples. It suggests that the repeatability could be improved enormously because the results presented in this thesis could be obtained just by adopting the new mechanism to control the contact conditions
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