Research and Implementation of Online Social Network User Role Identification Method

随着互联网和信息产业的发展，在线社会网络迅速成长，已经对互联网内容的产生以及用户的行为方式的改变产生了巨大的影响。因此，面向在线社会网络的分析对互联网信息监管、舆论导向以及市场经济领域的相关应用具有重大意义。 在线社会网络中的特定用户群体如意见领袖、网络水军等已成为影响网络舆论发展与社会热点事件走向的重要力量。提出一套行之有效的用户角色识别方法，通过用户的行为特征和网络属性对用户角色进行准确定位，针对特定类型用户采用不同的策略，便于对Web社会网络的监控和管理，此项研究具有着重要的意义。 本文完整的研究分析了用户角色识别方法的整个流程，并设计实现了相关的系统。 用户信息获取是整个用户识别...With rapid growth of the Internet and development of the information industry, online social networks are making a huge impact on the generation of the Internet contents as well as the changes of user behavior. So the analysis about online social network has a great significance for the regulation of the Internet information, the guidance of public opinion, and the application research of the mark...学位：工程硕士院系专业：软件学院_工程硕士(软件工程)学号：X201023062

An Investigation with Noise Trading of the Capital Market in China---Based on DSSW Model

噪声交易是指资本市场中使资产价格倾向于偏离其内在实际价值的一种力量或趋势。噪声交易者并不只是如FischerBlack所说的简单充当市场的润滑剂，被动地充当理性交易者的对手，他们也有主动的交易，比如说跟风（羊群效应）、技术分析等，甚至是有目的的交易，比如说价格操纵。这些行为在大部分情况下会形成一种系统性的趋势，进而会主动地影响市场。系统性的噪声交易风险是不能被分散化的，因而会参与资产价格的形成。 众多学者从不同的角度建立噪声定价模型。DeLong，AndreiShleifer，LawrenceSummers，RobertWaldmann（DSSW）四位学者从投资者效用角度建立的DSSW模型是...Noisy trading, which is introduced by Black in his 1986's paper, is a kind of trading strategy based on pseudo-information, defined relative to the valuable information. Roughly speaking, noisy trading would be inclined to drive financial asset price deviating to its inner real value and make the market seemingly chaotic. Despite this, arbitrage, a term that is stated very frequently by traditiona...学位：经济学硕士院系专业：王亚南经济研究院_金融学(含保险学)学号：2772007115223

Developmental Robotic 3D Reaching Based on Double-Network Architecture

手眼协调属于感觉运动的协调,是人认知能力的基础。这篇论文的目标是要模仿人类婴儿的发育过程来建立一个机器人系统,可以接近或者抓取物体。该文旨在应用发展模型中的“增量过程“,通过使用双神经网络在3d实验环境下来完成机器人抓取系统。这个机器人系统在全约束条件下开始发展,随着每个约束条件的成熟从而驱动双神经网络的训练,当所有的约束条件都释放,机器人系统就可以获得抓取能力。Reaching ability is a kind of human sensory motor coordination and is the foundation of human cognitive abilities.The objec.tive of this work is to imitate the developmental progress of human infant to create a robotic system which can reach or capture objects.The work proposes to employ a developmental model"incremental process"to implement such a robotic reaching system by using a dou.ble neural network system within 3D experimental environment.The robotic system starts to develop under fully constrained conditions,and the training of the double neural network is driven by each constraint has been saturated,when the all contained conditions have been overcome,the robotic system is able to own reaching ability.In addition,this paper delicately describes and discuss the experimental results

Research of prevention and treatment of herb components HJJB compound on non-alcoholic steatohepatitisin rats induced by high-fat diet

目的:探讨中药组分HJJB方(红景天苷、姜黄素、绞股蓝总苷、白术多糖)对高脂饮食诱导的大鼠非酒精性脂肪性肝炎的防治作用。方法:采用高脂饮食14周; 诱导大鼠非酒精性脂肪性肝炎模型。在造模第9周起,随机分为模型组,HJJB方高、低剂量组,罗格列酮组,灌胃给药6周。观察肝组织病理变化(HE染色); ,肝组织甘油三酯(TG)、游离脂肪酸(FFA)含量的变化,血清谷丙转氨酶(ALT)、谷草转氨酶(AST)、谷氨酰转肽酶(GGT)活性及TG、总胆; 固醇(TC)含量的变化。结果:模型组肝组织出现显著的肝细胞脂肪变性及空泡样变,肝组织TG、FFA含量较正常组显著升高(P<0.01),血清ALT; 、AST、GGT活性及TG、TC含量较正常组亦明显升高(P<0.01)。HJJB方高、低剂量组的上述病理改变显著减轻,肝组织TG、FFA含量及血; 清ALT、AST、 GGT、TG、TC水平显著低于模型组(P<0.01),其中HJJB方高剂量组的肝组织TG、FFA含量和血清ALT、AST、; GGT活性显著低于HJJB方低剂量组和罗格列酮组(P<0.05,P<0.01)。结论:中药组分HJJB方对高脂饮食诱导的大鼠非酒精性脂肪性肝炎具; 有良好的防治作用。Objective: To discuss the prevention and treatment of HJJB (salidroside,; curcumin, gypenoside and atractylodes macrocephala polysaccharide); compound on non-alcoholic steatohepatitisin rats induced by high-fat; diet. Methods: Non-alcoholic steatohepatitis model was induced by; high-fat diet for 14 weeks. From the ninth week, the rats were randomly; divided into model group, HJJB high-dose group, HJJB low-dose group and; rosiglitazone group, and were given gavage for six weeks. The observing; items including: pathological changes of liver tissue (HE staining); the; changesof contents of liver tissue triglyceride (TG) and free fatty acid; (FFA); the activities of serum alanine aminotransferase (ALT), aspartate; aminotransferase (AST), glutamyl transpeptidase (GGT) and contents of; serum total cholesterol (TC) and TG. Results: Significant hepatocellular; steatosis and vacuolar degeneration were observed inthe liver tissue of; the model group. The contents of TG and FFA in liver tissue of model; group were significantly higher than those of normal group (P<0.01), and; the activities of serum ALT, AST, GGT and the contents of TG and TC of; model group were higher than those of normal group too (P<0.01). Hepatic; pathological changes in the HJJB compound high-dose, low-dose groups; were all significantly meliorated. The levels of liver TG, FFA and serum; ALT, AST, GGT, TG and TC of HJJB high-dose group, HJJB low-dose group; were significantly lower than that of model group (P<0.01). In addition,; the contents of liver TG and FFA and serum ALT, AST, GGT of HJJB; compound high-dose group were lower than those of HJJB compound low-dose; and rosiglitazone group (P<0.05, P<0.01). Conclusion: HJJB compound does; well in the prevention and treatment of non-alcoholic steatohepatitis; induced by high-fat diet.国家自然科学基金项目; 浙江省自然科学基金项目; 浙江省中医药科技计划项

Research Progress on the Synthesis and Bioactivities of Indole-3-glyoxylamide Derivatives

综述了吲哚-3-乙醛酰胺类化合物(ID)的合成及生物活性的研究进展。ID具有抗肿瘤、抗病毒、抗菌、抗炎、腺苷受体功能调节、缓解疼痛和抗类风湿关节; 炎等多种生物活性,在药物化学领域有广泛应用。ID的合成方法主要为:吲哚母核与乙酰氯在乙醚(或THF)中于室温反应1; h制得含草酰氯结构的中间体;中间体与取代胺基化合物和二异丙基胺乙基胺反应合成ID。并对ID未来的应用作了简要展望。The synthesis and bioactivities of indole-3-glyoxylamide derivatives(ID); were reviewed with thirty two references. ID, which exhibited well; bioactivities in antitumor, antivirus, antibacterial, anti-inflammatory,; adenosine regulation, etc, were widely applied in pharmaceutical; chemistry. The main method for synthesizing ID was as follows: the; intermediate containing oxalyl chloride(M) was obtained by the reaction; of indole nuclear parent with acetylchloride in diethyl ether(or THF) by; reaction rt for 1h. ID were synthesized by the reaction of M with; substituted amino compound and N,N-diisopropylethylamine. The forecast; of the application of ID was briefly proposed.国家自然科学基金资助项

英国高校科研评估改革的新动向——基于“科研卓越框架2021”的分析

为提高科研拨款质量,保持并提升科研在全球的竞争力,英国从2019年1月起陆续发布了科研卓越框架2021 (Research Excellence Framework,REF2021)的评估指南、评估标准等文件。REF2021在传承和创新REF2014的基础上,强调公平、平等和透明原则,对科研产出、科研影响和科研环境等指标均做出了一定调整,减少了评估单元,增加了科研影响要素的权重,将科研对教学和学生的影响纳入评估范围之内等,体现出更加注重公平、强调质量和追求卓越的科研评估理念。REF2021重视科研成果的\"社会影响\"评估、基于学科特性的多元化评估、发展协同导向的跨学科评估等改革举措对当前我国实施\"双一流\"建设亟待解决的绩效评估课题具有重要的借鉴和启示意义

大数据时代计量经济学的新发展与新应用——第二届中国计量经济学者论坛(2018)综述

第二届中国计量经济学者论坛于2018年12月14—16日在中国科学院数学与系统科学研究院召开。本届论坛由东北财经大学、《经济研究》编辑部、厦门大学王亚南经济研究院与邹至庄经济研究中心、中国科学院预测科学中心联合主办,由中国科学院大学经济与管理学院承办。论坛旨在促进中国计量经济学理论研究与方法应用的发展。本届论坛邀请了美国麻省理工学院(MIT)Whitney Newey教授、美国南加州大学萧政教授、《经济研究》编辑部刘霞辉研究员、美国堪

Intervention effect of Chinese herb components HJJB Compound on PP1-DNA-PK-USF1 signaling pathway of non-alcoholic fatty liver rats

目的:基于蛋白磷酸酶(PP1)-DNA依赖的蛋白激酶(DNA-PK)-上游刺激因子1(USF1)信号通路,探讨中药组分HJJB方防治非酒精性脂肪; 肝(NAFLD)的作用机制。方法:采用高脂饮食诱导的大鼠NAFLD模型。设模型组、HJJB方组和罗格列酮组,分别灌胃给药6周。HE染色观察肝组织; 病理变化;测定肝组织甘油三酯(TG)、游离脂肪酸(FFA)含量的变化;肝组织PP1、DNA-PK、USF1; mRNA水平和蛋白含量的变化。结果:模型组肝组织出现显著的肝细胞脂肪变性及空泡样变,肝组织TG、FFA含量较正常组显著升高(P<0.01),肝组; 织PP1、DNA-PK、USF1; mRNA水平和蛋白含量较正常组均明显升高(P<0.01)。HJJB方组的上述病理改变明显减轻,肝组织TG、FFA含量较模型组显著降低(P<0.0; 1),肝组织PP1、DNA-PK、USF1; mRNA水平和蛋白含量较模型组显著降低(P<0.01)。结论:HJJB方能显著降低脂肪肝大鼠肝组织PP1; mRNA水平和蛋白含量,进而抑制其下游信号通路,这可能是其防治NAFLD的重要机制。Objective: Toexplore the mechanism of Chinese herb component HJJB; Compound on non-alcoholic fatty liver disease based on PP1-DNA-PK-USF1; signaling pathway. Methods: SD male rats were induced by high-fat diet; for nonalcoholic fatty liver disease model. The rats were randomly; divided into model group, HJJB group and rosiglitazone group, and were; given intragastric administration for six weeks. The observing items; including: liver pathology(HE staining); hepatic triglyceride(TG) and; free fatty acid(FFA) content; mRNA and protein content changes of; hepatic protein phosphatase 1(PP1), DNA-dependent protein kinase(DNA-PK); and upstream stimulating factor 1(USF1). Results: Significant hepatocyte; fatty degeneration and vesicle changes were observed in liver tissue of; model group. The hepatic TG and FFA contents of model group were; significantly higher than those of normal group(P<0.01), and mRNA levels; and protein contents of liver tissue PP1, DNAPK, USF1 in model group; were significantly higher than those in normal group(P<0.01). Hepatic; pathological changes in HJJB Compound group were meliorated, liver; tissue TG and FFA contents of HJJB Compound group were significantly; lower than those of model group(P<0.01), and mRNA levels and protein; contents of liver tissue PP1, DNA-PK, USF1 mRNA of HJJB Compound group; were significantly lower than those of model group(P<0.01). Conclusion:; HJJB Compound can significantly decrease mRNA level and protein content; of PP1 in the liver tissue of fatty liver rats, and then inhibit the; downstream signaling pathway of PP1, which may be an important mechanism; of HJJB Compound for prevention and treatment of non-alcoholic fatty; liver disease.国家自然科学基金项目; 浙江省自然科学基金项目; 浙江省中医药科技计划项

组织文化氛围、心理资本与组织归属感关系的实证研究

文章以472个企业员工为被试样本,运用相关分析、偏相关分析、回归分析及路径分析等统计方法考察了组织文化氛围、心理资本与组织归属感等变量之间关系。结果发现:(1)组织文化氛围、心理资本和组织归属感在受教育程度和工作岗位层面存在显著差异;心理资本、组织归属感存在显著的性别和工龄差异;(2)组织文化氛围与心理资本及组织归属感存在显著相关性和因果性;(3)组织文化氛围与心理资本相互作用,共同影响组织归属感,且组织文化氛围对组织归属感影响程度大