跨海集群工程节能减排关键技术研究

港珠澳大桥跨海集群工程囊括跨海桥梁、沉管隧道、离岸人工岛等多个领域。跨海集群工程由于建设期及运营期能耗巨大,国内外尚无节能减排的成套技术指导工程建设,成为制约跨海集群工程持续发展的瓶颈之一。本文依托港珠澳大桥跨海集群工程建设和运营过程,采用理论研究、数值分析及模拟测试等多种方法,开展了集群工程节能减排指标体系和长大沉管隧道通风、照明、人工岛运营节能减排关键技术研究,成果支撑了工程项目节能减排目标的实现

代谢综合征从毒论治病机探析

毒邪致病贯穿代谢综合征(metabolic symdrome,MS)发病的始终而成为重要的病机,MS发病的毒邪主要有痰毒、瘀毒和热毒,常形成痰、瘀、热毒相互交结的病理状态。认为机体的慢性低度炎症状态及其诱发的胰岛素抵抗,糖毒性、脂毒性就成了"毒邪"致病的物质基础,从而为临床的从毒论治奠定基础

代谢综合征与痰瘀毒

介绍了代谢综合征(metabolic syndrome,MS)的病因病机,认为其发病主要是痰瘀交阻、久蕴化热成毒,形成痰瘀毒相互交夹的病机,而现代医学认为代谢综合征的发病基础是慢性低度炎症,这是痰瘀毒病机的物质基础

代谢综合征的病因病机探讨

代谢综合征(metabolic symdrome,MS)的病因主要有过食肥甘、情志失调、运动过少、年龄增长及禀赋薄弱;MS的病机可以概括为:本虚标实,正虚以脾肾气虚为主,邪实则可归纳为肝郁、痰浊、瘀血、热毒。把握了MS的病因病机对中医的辨证论治具有重要意义

Population ecology of Ligophorus hamulosus on Liza carinatus

棱鮻(lIzA CArInATuS)样品于2000年12月--2001年10月取自广东湛江。按常规方法从鱼鳃上挑取小钩鲻鱼虫(lIgOPHOruS HAMulOSuS),进行压片、计数。结果显示:随着宿主体长的增长,小钩鲻鱼虫种群的平均密度、平均感染强度呈上升趋势;从12月到次年4月,其平均密度和平均感染强度上升,随后呈下降趋势,8月最低,10月略有回升;小钩鲻鱼虫种群在不同大小的宿主上和在不同季节均呈聚集分布。Ligophorus hamulosus was collected from the gills of Liza carinatus,which were captured in Zhanjiang,Guangdong Province from Dec,2000 to Nov.2001.The routine Parasitology methods were adopted in the study.The results showed that the abundance and the mean intensity of L.hamulosus population were increased with the increase of body length.From Dec.towards next Apr.the abundance and the mean intensity was increased,and afterwards they declined the lowest in Aug.but in Oct.they were increased slightly.The prevalence seemed to be decreased with the increase of the mean water temperature.The frequency distribution and the population parameters of L.hamulosus showed that the parasite populations in the host population group were over-dispersed for different body length and in different seasons.国家自然科学基金(39870144);广东省自然科学基金(980314

代谢综合征的辨证分型研究

目前代谢综合征的中医辨证分型主要依据个人经验、文献古籍记载,尚未统一,这样的辨证分型较易出现偏倚,可信度低。提出应该制定代谢综合征的中医证候临床调查表,进行大样本、前瞻性、多中心的中医证候临床流行病学调查,使用现代数理统计方法进行证候分类,探讨证型与发病机制有关临床检测指标的关系,通过"以方测证"方法来反证辨证分型的可靠性,从而建立代谢综合征的中医辨证论治体系

An Optical High Temperature Thermometer for Plume Measurement of Solid Propellant Rocket Motor

利用辐射光谱测量温度的原理,设计并制造了一种新型的非接触式光学辐射高温计.详细介绍该温度计的基本原理和标定方法,并将该温度计应用于火箭发动机喷管出口羽流的温度测量中,初步的实验结果和数值模拟结果相一致

Apoptosis of Human Esophageal Carcinoma Cell Line EC9706 Induced by Curcumin

目的:应用姜黄素处理人食管癌EC9706细胞,研究姜黄素对人食管癌EC9706细胞凋亡的诱导作用。方法:应用细胞计数、流式细胞仪、琼脂糖凝胶电泳、Hoechst染色、H.E染色和透射电镜检测经姜黄素诱导处理后人食管癌EC9706细胞的凋亡。结果:经姜黄素诱导处理后,人食管癌EC9706细胞生长抑制率达69.9%;细胞周期检测出现亚二倍体(亚G1期)细胞峰值,细胞凋亡率达23%;琼脂糖凝胶电泳显示出细胞凋亡典型的180-200 bp及其倍体的DNA"梯状"条带;Hoechst染色显示细胞核内出现浓染致密的固缩形态或颗粒状荧光;光镜和电镜下可见典型的细胞凋亡特征:细胞体积缩小,染色体凝集,可见有成群或单独存在的凋亡细胞,电镜下可见凋亡小体存在。结论:姜黄素能够有效诱导人食管癌EC9706细胞的凋亡,从而进一步为食管癌等恶性肿瘤疾病的治疗和凋亡机理的研究提供重要基础和科学依据.Objective: To study the apoptosis effects of the human esophageal carcinoma cell line EC9706 cells induced by curcumin(Cur). Methods: The apoptosis effects of EC9706 cells induced by curcumin were detected by cell count, flow cytometry analysis, light microscope and electron microscope. Results: After treated with curcumin, the proliferation of EC9706 cells was inhibited, and the inhibitory rate was 69.9%. The results of flow cytometry analysis showed that curcumin could induce the emergence of the phase of apoptosis, and the rate was 23%. Agarose gel electrophoresis revealed that cell DNA fragment exhibited characteristic "DNA ladder".Cell nucleus concentrated and appeared granular fluorescence by Hoechst33258 staining. Light microscope and electron microscope showed that the morphology of the cells treated with curcumin appeared shrinked, cell nucleus concerntrated, chromatin agglutinated, mitochondria swelled, and apoptosis body formed. Conclusion: This study suggested that curcumin could induce apoptosis of the human esophageal carcinoma cell line EC9706 effectively, and provided important foundation and research proofs to study more about the therapy of esophageal carcinoma, the malignant tumor and apoptosis mechanisms.国家自然科学基金项目(30470877

A New Method for the Measurement of Complexation Stability Constant and Average Coordination Number of Metallic Element with Polymer

建立了基于化学平衡理论模型以及凝胶过滤色谱(gfC)-电感耦合等离子体质谱(ICPMS)联用技术的高分子聚合物-金属配合物稳定常数、平均配位数测定新方法。以聚乙烯亚胺(PEI)和Cu2+为例,对形成的PEI-Cu配合物稳定常数、平均配位数进行测定,以0.02 MOl·l-1 HAC-nAAC为流动相,凝胶色谱柱分离大分子PEI-Cu配合物以及Cu的小分子配合物、游离态离子,最后用ICPMS测定不同形态金属元素的浓度;利用建立的化学平衡理论模型,计算PEI与金属离子形成配合物的稳定常数、平均配位数,测得25℃,PH4.1~5.3时,PEI-Cu配合物稳定常数为109.6~1010.7,平均配位数为1.0~1.3。建立的在线分离、测定方法具有快速、准确的特点,为高分子聚合物-金属配合物的研究提供新的技术手段。A new method using gel filtration chromatography(GFC) and inductively coupled plasma mass spectrometry(ICPMS) was developed for the measurement of complexation stability constant and average coordination number of the complex of metallic ion with polymer.As an example,the binding of PEI with Cu2+was shown and investigated.The macromolecular PEI-Cu complex and micromolecular species of Cu (Ⅱ) were firstly separated by a low efficiency GFC column with a mobile phase of 0.02 mol·L-1HAc-NaAc buffer,and then directly introduced into ICPMS for elemental analysis.The results of complexation stability constant and average coordination number characterized by putting the concentration of different species of metallic element into the equations of the novel chemical equilibrium model which was developed in this study.The results shown that the complexation stability constants(KPEI-Cu) were between 109.6and 1010.7and the average coordination numbers(n) were in the range of 1.0~1.3 when pH was changed from 4.1 to 5.3 at 25 ℃.This online,rapid and accurate method of GFC-ICPMS is a novel technique for the research of polymer-metallic complex.厦门大学近海海洋环境科学国家重点实验室自主创新项目(MELRI0703)资助项

304不锈钢表面十七氟癸基三甲氧基硅烷的缓蚀性能研究

采用电化学方法对十七氟癸基三甲氧基硅烷在304不锈钢表面的缓蚀性能进行了研究,结果发现,十七氟癸基三甲氧基硅烷对304SS有明显的缓蚀作用,增大了304不锈钢表面的电荷转移电阻,降低了自腐蚀电流密度并且提高了点蚀电位,缓蚀效率高达96%。国家科技支撑计划(2014BAE12B01