Research on Air Combat Decision-making for Cooperative Multiple Target Attack Using Heuristic Ant Colony Algorithm

协同多目标攻击空战决策是现代战机在超视距条件下进行协同空战的关键技术之一。它是寻求一个优化分配方案,将目标分配给各友机,力求使攻击效果最优。本文在对协同多目标攻击战术进行深入分析的基础上,提出了一种用于空战决策的启发式蚁群算法,该算法通过求解友机导弹对目标的最优分配来确定空战决策方案。仿真实验表明所提出的启发式蚁群算法对最优解的搜索效率明显优于基本蚁群算法,是一种求解协同多目标攻击空战决策问题的有效算法。The air combat Decision-Making(DM)for Cooperative Multiple Target Attack(CMTA)is one of the key techniques for modern fighters performing cooperative air combat under the Beyond Visual Range (BVR)condition.It is to find a proper assignment of the friendly fighters to the hostile fighters to achieve the optimal attack effect.In this paper,based on the deep analysis of the CMTA tactics,a Heuristic Ant Colony Algorithm(HACA)is proposed to solve the DM problem.The HACA obtains the DM solution by searching for the optimal assignment of the missiles of the friendly fighters to the hostile fighters.Simulation results show that the search efficiency of the proposed algorithm is obviously superior to that of basic Ant Colony Al- gorithm(ACA).It is an effective algorithm to deal with the DM problem for CMTA in air combat.国家自然科学基金(60604009);; 厦门大学985二期信息创新平台基金;; 福建省教委科技基金(JA05290

Air-Combat Decision-Making for UAVs Cooperatively Attacking Multiple Targets

中文摘要：针对超视距空战中多架无人机对空中的多个敌对目标进行协同攻击的决策问题进行了研究。首先，对空战威胁态势进行了分析，基于对各攻击目标至少分配一枚导弹的原则，将协同多目标攻击决策问题转化为导弹目标攻击配对的优化问题并建立其攻击效能评估模型。然后，提出了一种模拟退火遗传算法用于该决策问题的寻优。最后，通过所得最佳导弹目标分配个体求得最终协同攻击决策方案。仿真结果表明所提出的算法能有效地求解协同多目标攻击决策问题，其对最优解的搜索效率明显优于单一的遗传算法。 英文摘要：Abstract: Considering a Beyond Visual Range (BVR) air combat scenario with a group of UAVs versus multiple hostile airborne targets, the decision-making problem for Cooperative Attack on Multiple Targets (CAMT) was investigated. First, the air combat threat situation was analyzed. Based on the principle of each target to be attacked at least being assigned one missile, the decision-making for CAMT was converted into a Missile-Target Assignment (MTA) optimization problem with the establishment of the attack effectiveness evaluation model. Then, a Simulated Annealing Genetic Algorithm (SAGA) was proposed to find out the optimal solution to the MTA problem. Finally, the final decision-making solution to the CAMT was derived from the obtained best missile-target assignment individual. Simulation results show that the proposed method is more effective than Genetic Algorithm (GA) to deal with the decision-making problem for CAMT.基金项目：国家自然科学基金(60604009）；航空科学基金(2006ZC51039)；厦门大学985 二期信息创新平台项

Expression and Localization of Nucleophosmin During Curcumin-induced Apoptosis in the Immortalized Human Epithelial HaCaT Cells

该文以姜黄素诱导处理前后的人永生化表皮HACAT细胞为研究对象,对核仁磷酸蛋白(nuClEOPHOSMIn,nPM)在核基质中存在、分布及其与凋亡相关基因产物在姜黄素处理前后HACAT细胞中的共定位关系进行观察研究。WESTErn blOT结果显示,nPM存在于人永生化表皮HACAT细胞核基质蛋白组分中,并在姜黄素处理后的细胞核基质中表达下调,免疫荧光显微镜观察显示,nPM定位在核基质上,经姜黄素处理后出现分布位置与表达水平的变化,激光共聚焦显微镜观察可见nPM与HACAT细胞中凋亡相关基因bAX、bCl-2、MTP53和rb基因产物均存在共定位关系,但在姜黄素处理后细胞中其共定位分布区域出现变化。研究结果证实nPM是一种核基质蛋白,定位于核基质上,nPM在HACAT细胞诱导凋亡过程中的表达分布及其与凋亡相关基因产物的共定位现象值得进一步探索和研究。To explore the existence and distribution of nucleophosmin(NPM) in the nuclear matrix and its colocalization with the other apoptosis-related gene products following curcumin treatment in the human epithelial HaCaT cells,the nuclear matrix of HaCaT cells was extracted pre/post curcumin induced apoptosis.Western blot analysis showed that NPM existed in the fractions of nuclear matrix proteins and was down-regulated after curcumin treatment.The immunofluorescence observation revealed that NPM located in the nuclear matrix,curcumin treatment altered its expression level and distribution profile.The colocalization of NPM with the products of apoptosis-related repression genes,including Bax,Bcl-2,mtP53 and Rb,using laser scanning confocal microscopy,were evaluated,and substantial differences were observed following curcumin treatment.The results implied that NPM is a nuclear matrix protein,and the level of its expression and the colocalization with apoptosis-related gene products may play an important role during the apoptosis of HaCaT cells.国家自然科学基金(批准号:30871241)资助的课题~

单、双胎早产的高危因素及早产儿结局比较研究

目的探讨双胎早产与单胎早产高危因素的特点以及单、双胎早产儿的结局。方法回顾性分析广州医科大学附属第三医院2009年1月至2015年12月的单、双胎孕产妇与新生儿临床数据资料。结果研究期间在该院分娩的36 931例新生儿,双胎2080例,单胎34 851例,其中早产5877例,双胎早产1395例(双胎早产组),早产率为67.07%;单胎早产4482例(单胎早产组),单胎早产率为12.86%,总计早产发生率为15.91%,双胎早产率明显高于单胎,差异有统计学意义(P22~26岁组、>26~30岁组、>30~34岁组、>34~39岁组和>39岁组中,双胎早产率均明显高于单胎(单胎早产率对双胎早产率分别为:19.65%vs.64.86%、11.45%vs.70.85%、10.49%vs.68.16%、12.88%vs.65.41%、19.67%vs.64.51%、22.83%vs.68.42%,P均<0.05);单、双胎孕产妇不同孕周出生率比较,双胎在孕20~37周之间的出生率均高于单胎出生率;对早产的高危因素进行对比分析,双胎早产组中人工授精、体外受精-胚胎移植、羊水过多、胎膜早破、妊娠期糖尿病、妊娠期肝内胆汁淤积症的比例均明显高于单胎早产组,差异有统计学意义(1.79%vs.0.16%、1.79%vs.0.16%、2.79%vs.1.38%、32.48%vs.29.65%、19.50%vs.15.84%、2.22%vs.1.41%,P均<0.05);对新生儿的结局进行比较,单胎早产组中死胎、出生缺陷、新生儿呼吸窘迫综合征发生率均明显高于双胎早产组(8.68%vs.2.22%、11.20%vs.8.52%、15.35%vs.12.90%,P均<0.05),1 min、5 min、10 min Apgar评分双胎早产组明显高于单胎早产组,差异有统计学意义[(9.43±0.023)min vs.(9.06±0.026)min、(9.85±0.013)min vs.(9.69±0.016)min、(9.92±0.011)min vs.(9.81±0.014)min,P均<0.05]。结论双胎发生早产的风险显著高于单胎,与单胎早产相比,人工授精、体外受精-胚胎移植、羊水过多、胎膜早破、妊娠期糖尿病、妊娠期肝内胆汁淤积症等高危因素与双胎早产的关系更加密切,早产儿结局优于单胎早产组。国家重点研发计划(2016YFC1000405/2016YFC1000303);;国家自然科学基金(81571518

生物质气化与废弃物焚烧联合发电的技术经济分析

介绍了生物质气化与废弃物焚烧联合发电技术项目，确定了该项目经济效益的评价指标，定量计算了项目的投资回收期、净现值和内部收益率。同时还对燃料费用、上网电价和固定资产变化引起的敏感性进行分析。结果表明，该联合发电技术的动态投资回收期为9.05a，净现值为2770万元，内部收益率为15.82％，三个经济指标均符合行业标准。从经济角度看是完全可行的。 The item of the biomass gasification and waste incineration combined power was briefly introduced in the paper. The eyaluation index for the economic benefit of this combined power technology was confirmed. The pay back period, net present value and internal rate of return were quantitatively calculated. In addition, sensitivity of evaluation index arose by fuel cost, distribution electricity price and fixed assets was analyzed. The result point out that from the view of economy this combined power technology is feasible because its evaluation index accord with standard of electric industry

垃圾衍生燃料流化床燃烧过程中HCl和NOx的排放研究

在床总高为4040mm的变截面流化床中试规模装置内，研究垃圾衍生燃料（RDF）在气化和燃烧不同阶段中NO2和HCl的生成特性。含NaCl的垃圾衍生燃料在流化床内燃烧，燃烧低于640℃时，Ca（OH）2的脱氯效果比较好；但随着温度升高，烟气中HCl的体积分数迅速增长，但脱氯效果明显受到CaCl2化学反应平衡的限制。燃烧状况特别是氧的体积分数对NO2的生成影响比较大。含氮量高的RDF燃烧产生NO2的体积分数明显高于低含氮燃料所产生的