Use of Stem Cell Therapy in COVID-19

Severe acute respiratory syndrome coronavirus 2 is known to cause the new coronavirus disease 2019 (COVID-19), in which many organs and systems such as the lung, heart, and immune system can be severely affected. Currently, the treatment process is generally based on supportive and palliative care. Some potential drugs are being tested for treatment. At this point, perhaps a promising treatment method for many diseases in the future seems to be stem cell therapy in recent times. Stem cell therapy in COVID-19 may be a treatment method that can play an important role, especially in resistant and severe cases. In this review, we summarized the potential mechanisms of stem cell therapy and developments in this treat ment modality

Correlation of Premalign Servicovaginal Smear Results With Colposcopy and Leep

Aim: In this study, it was aimed to evaluate the degree of compatibility between patients who underwent smear, colposcopy and LEEP / conization stages of cervical cancer screening. Materials and Methods: From January 2010 to December 2017, 145 patients who had undergone LEEP treatment for our Gynecology and Obstetrics outpatient clinic were included in the study. The compliance scores between LEEP, colposcopic biopsy and smear pathology results of these patients were retrospectively analyzed. For the statistical analysis, NCSS (Number Cruncher Statistical System) 2007 (Kaysville, Utah, USA) program was used for statistical analysis.Results: When HPV DNA result was positive and the pathology results of LEEP and colposcopy were examined, CIN 2 + 3 was detected in 62.9% of the cases and this rate was found to be significantly high. When the histopathological results of LEEP and colposcopy were compared, 14.5% of cases with colposcopy result CIN 1 and 35.2% of cases with CIN 2 had the same histopathologic result after LEEP. Noteworthy was the presence of CIN 1 in 2.1%, CIN 2 + 3 in 2.8%, and invasive carcinoma in 1 case without lesions after colposcopy.Conclusion: Smear, colposcopy and LEEP should be used as complementary to each other when appropriate patients for excisional therapy are identified. Clinical correlation of histopathologic results of these methods is important.When premalign lesions are detected, it can be considered that the biopsy done with colposcopy is reliable. However, for definite diagnosis and treatment, the cervical conization method should be accepted as the gold standard and information should be given to the patient in this way. Therefore, patients need to be directed to excision treatment if needed

Knowledge Level Assessment Survey of Nurses at Tekırdag Namik Kemal University Medical Research Center, About HPV Vaccination

Aim:Cervical cancer is a common and mostly fatal gynecological malignancy. HPV vaccination is a secure and efficient procedure to prevent cancer before the first sexual intercourse. Designed to prevent the majority of invasive cervical cancer, quadrivalent (HPV 6/11/16/18) and bivalent (HPV 16/18) vaccines have been available since 2006 and 2007. These vaccines can prevent most cases of cervical cancer if given before a girl or woman is exposed to the virus. The Advisory Committee on Immunization Practices- ACIP suggests that girls should be vaccinated around the age of 12 years, even series can be started at age of 9 years.Material and Method:Between the dates of 1 January – 28 February 2018 at Tekirdağ Namık Kemal University Medical Research Center 50 nurses who have daughters, answered the questions of knowledge level assesstment survey about HPV vaccination.Results:Although %88 of the nurses know how and why to screen cervical cancer, only %32 of them had regular gynecological examination and cervical cancer screening. The rate of informing patients about HPV vaccination at gynecologist appointments of these 50 nurses, is %15.Conclusion:Nurses, providing healthcare services and health education to the community, have sufficient knowledge about HPV vaccination, which is indispensable for preventing cervical cancer. However, their trust in HPV vaccines is at very low levels. Additionally, our research shows that gynecologists cannot inform their patients efficiently due to not having HPV vaccination on National Immunizations Programme and additional costs

Knowledge Level Assessment Survey of Nurses at Tekırdag Namik Kemal University Medical Research Center, About HPV Vaccination

Amaç: Serviks kanseri kadınlar arasında sık görülen ve ölümlere yol açan önemli bir jinekolojik malignitedir. İlk cinsel ilişki öncesinde enfeksiyona karşı etkili, güvenilir ve uygulanabilir bir aşı olan HPV aşısı ile bağışıklamanın sağlanması korunmada oldukça etkilidir. Serviks kanserinden korunmak için 2006’da kuadrivalan, 2009’da bivalan, nonavalan HPV aşıları geliştirilmiştir. Amerikan Bağışıklama Uygulamaları Danışma Komitesi (The Advisory Committee on Immunization Practices-ACIP) kız çocuklarının rutin olarak 11- 12 yaş civarında aşılanmasını, hatta bu sınırın dokuz yaşa çekilmesini önermektedir. Materyal ve Metot: Tekirdağ Namık Kemal Üniversitesi Sağlık Uygulama ve Araştırma Merkezi’nde yapılan “kız çocuk ebeveyni hemşire annelerin HPV aşısı hakkında bilgi düzeyi değerlendirme anketi”, araştırma Merkezi’nde hemşire olarak görev yapan 50 anneye 1 Ocak- 28 Şubat 2018 tarihleri arasında yüzyüze olarak uygulandı. Bulgular: Serviks kanseri taramasının nasıl yapıldığı çalışmaya katılan hemşire ebeveynlerin %88’i tarafından bilindiği halde düzenli jinekolojik muayene ve düzenli serviks kanser taraması %68’i tarafından yaptırılmamıştır. Çalışmamıza katılan hemşire ebeveyn annelerin kadın hastalıkları ve doğum uzmanı başvurularında HPV aşısı ile ilgili bilgilendirilme oranları ele alındığında ise bilgilendirilme oranı %15 olarak tespit edilmiştir. Sonuç: Topluma sağlık hizmeti sunan, sağlık konusunda eğitim ve danışmanlık görevleri bulunan hemşirelerin servikal kanser için primer korumada rolü olan HPV aşısı hakkında bilgi sahibi oldukları görülmüş ancak aşıya karşı olan güvenleri çok düşük düzeyde bulunmuştur. Ayrıca çalışmamızda kadın hastalıkları ve doğum hekimleri tarafından da gerek maliyet gerek ulusal aşı programı kapsamında olmaması nedeniyle HPV aşısı hakkında bilgilendirmenin yeterli düzeyde yapılamadığı sonucuna varılmıştırAim: Cervical cancer is a common and mostly fatal gynecological malignancy. HPV vaccination is a secure and efficient procedure to prevent cancer before the first sexual intercourse. Designed to prevent the majority of invasive cervical cancer, quadrivalent (HPV 6/11/16/18) and bivalent (HPV 16/18) vaccines have been available since 2006 and 2007. These vaccines can prevent most cases of cervical cancer if given before a girl or woman is exposed to the virus. The Advisory Committee on Immunization Practices- ACIP suggests that girls should be vaccinated around the age of 12 years, even series can be started at age of 9 years. Material and Method: Between the dates of 1 January – 28 February 2018 at Tekirdağ Namık Kemal University Medical Research Center 50 nurses who have daughters, answered the questions of knowledge level assesstment survey about HPV vaccination. Results: Although %88 of the nurses know how and why to screen cervical cancer, only %32 of them had regular gynecological examination and cervical cancer screening. The rate of informing patients about HPV vaccination at gynecologist appointments of these 50 nurses, is %15. Conclusion: Nurses, providing healthcare services and health education to the community, have sufficient knowledge about HPV vaccination, which is indispensable for preventing cervical cancer. However, their trust in HPV vaccines is at very low levels. Additionally, our research shows that gynecologists cannot inform their patients efficiently due to not having HPV vaccination on National Immunizations Programme and additional costs

Effects of carvedilol therapy on arrhythmia markers in patients with congestive heart failure

The aim of this study was investigate the effects of carvedilol therapy on ventricular repolarization characteristics as assessed by QT dispersion (QTd) and heart rate variability (HRV) in patients with heart failure

Sodium bicarbonate, N-acetylcysteine, and saline for prevention of radiocontrast-induced nephropathy. A comparison of 3 regimens for protecting contrast-induced nephropathy in patients undergoing coronary procedures. A single-center prospective controlled trial

Background Several protective therapies have been developed to prevent contrast-induced nephropathy (CIN). We aimed to investigate the efficacy of sodium bicarbonate by comparing 2 other regimens, including combination of N-acetylcysteine (NAC) plus sodium chloride and sodium chloride alone, to prevent CIN in patients undergoing cardiovascular procedures