Construction of Controlled Drug Release System based on Photothermal Conversion Property of Polypyrrole

聚吡咯（PPy）是一种有机导电聚合物，利用其优异的导电性、生物相容性以及较强的机械性能，可用作药物载体，并用电控制药物释放。此外，聚吡咯还具有较强的近红外吸收和理想的光热转换能力，聚吡咯纳米粒子（PPyNPs）的光热转化效率可达44.7%。结合这些优异性能，可实现聚吡咯材料在药物输送、生物传感及光热治疗等多个领域的应用。 本论文利用聚吡咯的光热转换性质，构建了两类基于近红外激光触发释药的药物释放体系： （1）月桂酸和聚乳酸复合的药物载体点阵，点阵中每一个点由两部分组成，包括内层药物核心和外部保护层。保护层由月桂酸、聚乳酸和聚吡咯纳米粒子构成。聚吡咯纳米粒子具有优异的光热转换能力，近红外光照...Polypyrrole (PPy) as an organic conductive polymer, due to excellent electrical conductivity, biocompatibility and strong mechanical properties, PPy can be used as drug carrier, and controlled drug release by electrical stimulation. In addition, PPy also has strong near-infrared absorption and ideal photothermal conversion capability, the photothermal conversion efficiency of PPy nanoparticles up ...学位：理学硕士院系专业：材料学院_生物医学工程学号：3142013115013