1,317 research outputs found

    Unprecedented access? Women instrumentalists in punk bands 1976-1984: an exploration

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    This study has been undertaken because of a gap in popular music and subcultural history. The significance of the first large influx of women into rock music, as punk instrumentalists in the late 1970s, has been underplayed; instead, women punks have been stereotypically documented. Girls' and womens' roles as producers of music, and their consequent contribution to the sound of punk music, have been subjected to a collective amnesia. Four areas of literature have been reviewed to clarify the reasons for, and extent of the gap: writings on subcultures and scenes, writings on women in rock and pop, writings on the socio-political context, and writings on punk. One of the main foci of the study has been to identify the reasons for the fading away of the presence of women instrumentalists in the early 1980s. I wanted to discover why this phenomenon had such a short time span. The primary research involved a newspaper survey (300 local papers were contacted across Britain) from which 24 useful questionnaires were gleaned; I interviewed 15 women who were in bands at the time, as well as a radio DJ, record company owner, band manager, and several male band members and political activists from the scene. Fanzines, music papers and the feminist magazine Spare Rib have also been referred to extensively. I have also had my own recollections of the time to draw upon. Following the literature review, the study is divided into sections on Access (enabling and empowering factors), Media Gatekeepers and Cultural Intermediaries (external controls and filters), The Brighton Scene (a case study of my own local punk envirom-nent), Noise, Violence and Femininity (the practice of music making by these women, and the resistance to it), the Aftermath (exploring factors contributing to the ending of the moment), and Conclusions

    Gender Ventriloquism in Studio Production

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    A process of ventriloquism, with male producers speaking through the mouthpieces of the women they produce, can reinforce gender delineations in pop. After discussing ventriloquism in pop and demonstrating different ways in which this has happened using historical examples, the authorā€™s original interviews with women who record male artists are examined to discover whether a similar process takes place when roles are reversed. The author concludes that aspects of ventriloquism are inherent in production, although some women producers have questioned gender roles during this process. She also notes that as more female mediators enter the profession, we may hear more authentic expressions of womenā€™s identities in popular music

    Lipid antigens and immunoregulatory iNKT cells in the prevention and treatment of type 1 diabetes and related autoimmune diseases

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    Invariant natural killer T (iNKT) cells constitute an important regulatory arm of the immune system. Defects in the number and activities of iNKT cells have been linked to the development of autoimmune diseases. The glycoprotein CD1d plays an integral part in the recognition and presentation of lipid antigens such as Ī±-galactosylceramide (Ī±-GalCer) to iNKT cells, producing a variety of anti-inflammatory (TH_H2) cytokines, such as interleukin-4 (IL-4), and pro-inflammatory (TH_H1) cytokines, such as interferon-Ī³ (IFN-Ī³). A decreased number of iNKT cells and defects in their capacity to produce TH_H2 cytokines is associated with autoimmune diseases, such as type 1 diabetes (T1D). Ī±-GalCer stimulates both TH_H1 and TH_H2 responses. Some analogues of Ī±-GalCer preferentially induce the production of TH_H2 cytokines, highlighting the possibility that such compounds could have therapeutic potential with regards to TH_H1 cell-mediated autoimmune diseases, such as T1D and SLE. A library of Ī±-GalCer analogues was synthesised and their ability to modulate immune responses analysed. Altering the length of the phytosphingosine chain in Ī±-GalCer analogues was shown to drastically affect the TH_H1:TH_H2 response, with truncated phytosphingosine chains of 9 carbons skewing the response towards a predominantly TH_H2 response. Substituting the galactose sugar head for glucose (Ī±-GlcCer) or L-fucose (Ī±-L-FucCer) also elicited differences in the immunological profile of Ī±-GalCer analogues, with lymphocytic proliferation being greatest in the galactose analogue, followed by L-fucose, followed by a glucose analogue. These differences in activity were also mirrored in the cytokine responses of the analogues, suggesting the C4ā€™ hydroxyl group plays a key part in antigen recognition and activity. Analogues incorporating 2 double bonds in the NN-acyl chain exhibited TH_H2 cytokine profiles on a par with Ī±-GalCer, yet dramatically decreased TH_H1 responses were observed. They also considerably delayed the clinical presentation of glucosuria in NOD mice. These results have provided important insights into the nature of antigen binding with CD1d, recognition of the antigen by iNKT cell receptors, and how such factors play a role in skewing the immune response, thus highlighting areas where structural diversity could be introduced in order to exploit immunomodulating potential, and find a possible prophylactic therapy for the prevention and treatment of autoimmune diseases, such as T1D

    The Smartest Guise in the Room: Why America is Doomed to Repeat an Enron-Like Scandal

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    There is no question that Enron has brought change to the landscape surrounding business practices both domestically and globally. After the Emon Scandal occurred, Congress passed a very controversial and groundbreaking legislative act known as the Sarbanes-Oxley Act as a means of stopping the conditions that made this widespread scandal possible. There are several reasons why another Emon-type Scandal is prone to repeat itself in the near future. One of the reasons is that Sarbanes-Oxley is not the perfect bill. Although the controversial Sarbanes-Oxley is a valiant effort to reform the environment that fostered Enron, there are major gaps and faults in the bill. Another reason is that there is no present evidence that proves the perception of accounting and finance has changed considerably. For there to be less of a chance of another scandal, it would be an absolute necessity that accounting and finance ethical standards shift considerably. These key causes of the Enron Scandal have gone unaccounted for (no pun attended), and until they are addressed the door is open for future corporate indignity
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