965 research outputs found

    Enhanced Trustworthy and High-Quality Information Retrieval System for Web Search Engines

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    The WWW is the most important source of information. But, there is no guarantee for information correctness and lots of conflicting information is retrieved by the search engines and the quality of provided information also varies from low quality to high quality. We provide enhanced trustworthiness in both specific (entity) and broad (content) queries in web searching. The filtering of trustworthiness is based on 5 factors – Provenance, Authority, Age, Popularity, and Related Links. The trustworthiness is calculated based on these 5 factors and it is stored thereby increasing the performance in retrieving trustworthy websites. The calculated trustworthiness is stored only for static websites. Quality is provided based on policies selected by the user. Quality based ranking of retrieved trusted information is provided using WIQA (Web Information Quality Assessment) Framework

    Hormonal Regulation of Cutaneous Melanoma: A Brief Review of In Vivo and In Vitro Studies and Its Clinical Implication

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    Skin is an endocrine organ. Skin produces various hypothalamic, pituitary, adrenal and sex steroid hormones. This raises the question whether skin cancer melanoma is a hormone dependent cancer. But, a review of in-vivo and in-vitro studies suggested that melanoma could be a hormone responsive cancer or hormone sensitive cancer. In fact, previous clinical study showed that menstruating females were better protected in melanoma than post-menopausal women and men of any age. However, the study did not show any direct effect of steroid hormone on melanoma cells. Our in-vitro study showed that progesterone, a female sex hormone significantly inhibited human melanoma (BLM) cell growth. Progesterone inhibitory effect on other melanoma cell lines was also reported by Fang et al., Moroni et al. and Kanda and Watanbe. So, it was hypothesized that progesterone could be protecting menstruating females in melanoma. Our further research showed that progesterone action was mediated by a specific suppression of pro-inflammatory cytokine IL-8. Several in-vivo and in-vitro studies showed the importance of IL-8 in the regulation of melanoma growth. Hence, IL-8 could be considered as a potential target for melanoma treatment

    Is Melanoma a Hormone-Dependent Cancer or a Hormone-Responsive Cancer?

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    Melanoma, a potentially fatal form of skin cancer is on the rise. This review not only underlines the close connection between skin and endocrine system, but also lists evidences from multiple sources epidemiological, clinical, previous in vivo and in vitro studies regarding the involvement of sex steroids in melanoma. Incidentally, clinical studies underscored the involvement of sex steroids in the protective function in melanoma in menstruating females. But, none of these studies identified the sex steroids involved in the protective function in melanoma in menstruating females. The sex steroid involved in this innate protection in melanoma in menstruating females has not been investigated by scientists, though advances have been made in immunotherapy with accompanying side effects. In this context, our in vitro studies on mouse and human melanoma cell lines, along with literature survey, pointed to progesterone as the possible female sex steroid involved in the protective function in melanoma. Based on our findings and previous studies, it is concluded in this review that melanoma is not a hormone-dependent cancer. But, it may be a hormone-sensitive or responsive cancer, as hormones (sex steroids) inhibited melanoma cell proliferation in vitro. This new understanding will help in developing new therapy or target for melanoma treatment

    A Training Assistant Tool for the Automated Visual Inspection System

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    This thesis considers the problem of assisting a human user setting up an automated Visual Inspection (VI) system. The VI system uses a stationary camera on an automobile assembly line to inspect cars as they pass by. The inspection process is intended to identify when parts have been missed or incorrect parts have been assembled. The result is reported to a human working on the assembly line who then can take corrective actions. As originally developed, the system requires a setup phase in which the human user places the camera and records a video of at least 30 minutes length to use for training the system. Training includes specifying regions of cars passing by that are to be inspected. After deployment of a number of systems, it was learned that users could benefit from being provided guidance in best practices to delineate training data. It was also learned that users could benefit from simple visual feedback to ascertain whether or not an inspection problem was suitable for a VI system or if the problem was too challenging. This thesis describes a few methods and a new software tool intended to address this need

    An Efficient Technique for Detection and Prevention of SQL Injection Attack using ASCII Based String Matching

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    AbstractWith the rise of the Internet, web applications, such as online banking and web-based email, have become integral to many people's daily lives. Web applications have brought with them new classes of computer security vulnerabilities, such as SQL injection. It is a class of input validation based vulnerabilities. Typical uses of SQL injection leak confidential information from a database, by-pass authentication logic, or add unauthorized accounts to a database. This security prevents the unauthorized access to your database and also it prevents your data from being altered or deleted by users without the appropriate permissions. Malicious Text Detector, Constraint Validation, Query length validation and Text based Key Generator are the four types of filtration technique used to detect and prevent the SQL Injection Attacks from accessing the databas

    Nanostructured copper particles-incorporated Nafion-modified electrode for oxygen reduction

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    The electrocatalytic activity of nanostructured copper particles (represented as Cunano) incorporated Nafion (Nf) film-coated glassy carbon (GC) electrode (GC/Nf/Cunano) towards oxygen reduction was investigated in oxygenated 0.1 M phosphate buffer (pH 7.2). The electrodeposited Cunano in Nf film was characterized by atomic force microscopy (AFM) and X-ray photoelectron spectroscopy (XPS). The electrocatalytic activity of Cunano at the modified electrode towards oxygen reduction was studied using cyclic voltammetry technique. The molecular oxygen reduction at the GC/Nf/Cunano-modified electrode started at a more positive potential than at a bare GC electrode. A possible reaction mechanism was proposed in which oxygen reduction may proceed through two-step two-electron processes at the GC/Nf/Cunano electrode. The GC/Nf/Cunano electrode shows higher stability for oxy gen reduction in neutral solution and the electrode may find applications in fuel cells

    Core-shell Au/Ag nanoparticles embedded in silicate sol-gel network for sensor application towards hydrogen peroxide

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    The electrocatalytic activity of core-shell Au100-x Agx (x = 15, 27, 46, and 60) bimetallic nanoparticles embedded in methyl functionalized silicate MTMOS network towards the reduction of hydrogen peroxide was investigated by using cyclic voltammetry and chronoamperometric techniques. Core-shell Au/Ag bimetallic nanoparticles were characterized by absorption spectra and HRTEM. The MTMOS silicate sol-gel embedded Au73Ag27 core-shell nanoparticles modified electrode showed better synergistic electrocatalytic effect towards the reduction of hydrogen peroxide when compared to monometal MTMOS-Aunps and MTMOS-Agnps modified electrodes. These modified electrodes were studied without immobilizing any enzyme in the MTMOS sol-gel matrix. The present study highlights the influence of molar composition of Ag nanoparticles in the Au/Ag bimetallic composition towards the electrocatalytic reduction and sensing of hydrogen peroxide in comparison to monometal Au and Ag nanoparticles

    A Comparative Study of CN2 Rule and SVM Algorithm and Prediction of Heart Disease Datasets Using Clustering Algorithms

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    In this paper, we discuss diagnosis analysis and identification of heart disease using with data mining techniques. The heart disease is a major cause of morbidity and mortality in modern society; it is extremely important but complicated task that should be performed accurately and efficiently. It is an huge amount data of leads medical data to the need for powerful data analysis tools are availability on the data mining technique. They have long to been an concerned with applying for statistical and data mining tools and data mining techniques to improve data analysis on large datasets. In this paper, to proposed system are implemented to find out the heart disease through as to compared with the some data mining techniques are Decision tree, SOM, CN2 Rule and K-Means Clustering the data mining could help in the identification or the prediction of high or low risk of Heart Disease.Keywords: Data Mining, Heart Disease, Decision tree, SOM, CN2 Rule and cluster
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