The influence of the visual elements of cover design on the appeal of art and cultural magazines: case study is book fare in Oulu

Design of magazines - a complex and time-consuming process, often requiring custom solutions. Developers need to know what impact on the visual component of information influence on the audience. The purpose of this case is to gain an understanding of what kind of visual elements of paper media influence on the choice of viewer. As a particular type of magazine were chosen art and cultural magazine with a reason to narrow research and to get depth knowledge about this topic. The study is structured that in the first chapter the information about purpose and research questions is provided. Second chapter describes research materials and methodology that were used to collect data. The third chapter gives the literature review that focus subjects of the study. In the chapters four, the results of the research is analysed and conclusions are made. After all chapters made generalised conclusion using data from the literature review and data collected from the interviews

Analysis of the role of the p47 GTPase IIGP1 in Resistance against Intracellular Pathogens

IIGP1 is a member of the p47 GTPase family of IFNγ-induced proteins, which are among the most potent presently known mediators of cell-autonomous resistance against intracellular bacterial and protozoan pathogens in the mouse. From all studied members of this family IIGP1 is the best characterized with respect to biochemical characteristics and enzymatic activity in vitro, as well as membrane binding properties and dynamic behavior in cells. The role of the protein in intracellular defense was however, unknown and this study was set as an initial attempt to reveal it. This thesis describes the generation of an IIGP1 deficient mouse and analysis of the susceptibility of this animal to pathogens from protozoan and bacterial origin, which employ diverse strategies for host cell invasion and intracellular survival and replication. Despite having intact adaptive immune system, the IIGP1 deficient mice showed higher incidence of development of cerebral malaria after infection with Plasmodium berghei sporozoites. In addition, IIGP1 deficient astrocytes exhibited a partial loss of IFNγ-induced inhibition of Toxoplasma gondii growth. IIGP1 deficient animals were not susceptible to infection with Leishmania major, Listeria monocytogenes, Chlamydia trachomatis and Anaplasma phagocytophilum. From the analysis of the obtained data in the context of the intracellular lifestyle of the pathogens involved in this study, we concluded that IIGP1 seems to be specifically involved in defense against protozoan parasites, which like Pl. berghei and T. gondii reside in non-fusigenic parasitophorous vacuoles after entering cells. The mechanisms of IIGP1-dependent protection of cells against these pathogens remain to be studied

Editorial for the First Workshop on Mining Scientific Papers: Computational Linguistics and Bibliometrics

The workshop "Mining Scientific Papers: Computational Linguistics and Bibliometrics" (CLBib 2015), co-located with the 15th International Society of Scientometrics and Informetrics Conference (ISSI 2015), brought together researchers in Bibliometrics and Computational Linguistics in order to study the ways Bibliometrics can benefit from large-scale text analytics and sense mining of scientific papers, thus exploring the interdisciplinarity of Bibliometrics and Natural Language Processing (NLP). The goals of the workshop were to answer questions like: How can we enhance author network analysis and Bibliometrics using data obtained by text analytics? What insights can NLP provide on the structure of scientific writing, on citation networks, and on in-text citation analysis? This workshop is the first step to foster the reflection on the interdisciplinarity and the benefits that the two disciplines Bibliometrics and Natural Language Processing can drive from it.Comment: 4 pages, Workshop on Mining Scientific Papers: Computational Linguistics and Bibliometrics at ISSI 201