A Deep Reinforcement Learning-Based Model for Optimal Resource Allocation and Task Scheduling in Cloud Computing

The advent of cloud computing has dramatically altered how information is stored and retrieved. However, the effectiveness and speed of cloud-based applications can be significantly impacted by inefficiencies in the distribution of resources and task scheduling. Such issues have been challenging, but machine and deep learning methods have shown great potential in recent years. This paper suggests a new technique called Deep Q-Networks and Actor-Critic (DQNAC) models that enhance cloud computing efficiency by optimizing resource allocation and task scheduling. We evaluate our approach using a dataset of real-world cloud workload traces and demonstrate that it can significantly improve resource utilization and overall performance compared to traditional approaches. Furthermore, our findings indicate that deep reinforcement learning (DRL)-based methods can be potent and effective for optimizing cloud computing, leading to improved cloud-based application efficiency and flexibility

Boosted Dark Matter at the Deep Underground Neutrino Experiment

We investigate the detection prospects of a non-standard dark sector in the context of boosted dark matter. We consider a scenario where two stable particles have a large mass difference and the heavier particle accounts for most of dark matter in our current universe. The heavier candidate is assumed to have no interaction with the standard model particles at tree-level, hence evading existing constraints. Although subdominant, the lighter dark matter particles are efficiently produced via pair-annihilation of the heavier ones in the center of the Galaxy or the Sun. The large Lorentz boost enables detection of the non-minimal dark sector in large volume terrestrial experiments via exchange of a light dark photon with electrons or nuclei. Various experiments designed for neutrino physics and proton decay are examined in detail, including Super-K and Hyper-K. In this study, we focus on the sensitivity of the far detector at the Deep Underground Neutrino Experiment for boosted dark matter produced in the center of the Sun, and compare our findings with recent results for boosted dark matter produced in the galactic center.Comment: 11 Pages, 5 Figure

STUDI PENGARUH PEMANASAN BERULANG DAN WAKTU TAHAN PEMANASAN MINYAK GORENG TERHADAP NILAI KOEFISIEN VISKOSITAS

Pengukuran nilai koefisien viskositas minyak goreng kelapa sawit menggunakan metode bola jatuh telah berhasil dilakukan. Penentuan nilai viskositas dilakukan dengan mengukur waktu tempuh jatuhnya bola ke dalam minyak, kerapatan bola dan minyak, diameter dan massa dari bola, dan kecepatan bola di dalam minyak.. Pengukuran viskositas minyak kelapa sawit dilakukan pada produk minyak yang beredar di pasaran yaitu minyak kemasan A, B, C, D dan minyak curah. Kemudian dua produk dipilih untuk dilihat perubahan viskositas terhadap variasi pemanasan berulang dan waktu tahan pemanasan untuk sekali pemakaian. Hasil penelitian didapatkan bahwa viskositas dengan nilai paling tinggi dimiliki oleh minyak curah dan viskositas dengan nilai paling rendah dimiliki oleh minyak kemasan A. Selanjutnya didapatkan bahwa viskositas minyak yang dipanaskan selama 60 menit hampir sebanding dengan viskositas minyak dalam 6 kali pemakaian dengan waktu tahan selama 30 menit. Minyak goreng kelapa sawit dengan nilai viskositas yang lebih tinggi akan mendidih pada suhu yang lebih tinggi dan waktu pemanasan yang lebih lama. Minyak goreng kelapa sawit yang digunakan secara berulang tetapi dengan waktu penggunaan yang singkat lebih baik dari pada minyak goreng kelapa sawit yang dipakai satu kali namun dalam penggunaan yang lebih lama. Kata kunci: viskositas, minyak kelapa sawit, metode bola jatu

Role of Nucleosome Remodeling Factor (NURF) in Tumorigenesis Using a Breast Cancer Mouse Model

Understanding the impact of epigenetic mechanisms on tumorigenesis is essential, as epigenetic alterations are associated with tumor initiation and progression. Because epigenetic changes are reversible, they are potential targets for cancer therapy. Nucleosome Remodeling Factor (NURF) is a chromatin-remodeling complex that regulates gene expression by changing nucleosome positioning along the DNA sequence. Previous studies have shown a role for NURF in embryonic development as well as regulating genes involved in tumor progression. In this work we investigated the impact of eliminating NURF function in tumorigenesis in vivo. BALB/c mice challenged with syngeneic 67NR breast cancer cell lines, injected into the mammary fat pad, lacking NURF, due to knockdown of its essential subunits Bptf, showed reduction in tumor growth comparing to control tumors. The observed reduction in tumor growth was abrogated in immunodeficient mice lacking a functional immune system. Bptf KD and control 67NR cells grew at similar rates in vitro. Similar findings were observed in our lab using 66cl4 breast cancer cell lines. Using immunofluorescence staining, no significant difference in CD8+, CD4+, NK and MDSC cells infiltrations into the tumor microenvironment was observed in 66cl4 tumors. Preliminary results from 67NR tumors suggested more CD4+ and CD8+ cells. Gene expression profile of tumor tissues from BALB/c mice injected with 67NR and 66cl4 cell lines showed enrichment of genes associated with immune response. Our findings suggested a role of the immune system in targeting tumor cells lacking Bptf in vivo

Human Health Risk Assessment of Trace Metals in Indoor Dust.

The risk associated with exposure to heavy metals found in indoor dust is viewed as a serious hazard to human health, and heavy metal pollution of the environment is a major concern on a global scale. Accordingly, the current study set out to assess the heavy metals concentrations in indoor dust and the hazards they bring in adults and children. 71 indoor dust samples were collected from wooden flooring and analyzed using ICP-MS apparatus. Comparing our findings to the Environmental Protection Agency\u27s acceptable risk criteria showed that lead (Pb), manganese (Mn), Chromium (Cr), copper (Cu), and zinc (Zn) had high absorbed daily dosages in both children and adults. The median CR values for Pb indicated a significant probability of developing cancer. As a result of the non- bioaccumulation nature of trace metals in the body, the mean values of CR for the remaining elements were lower risk in both children and adults and have not exceeded the permissible limit set by USEPA, suggesting that these metals may not pose a future non- carcinogenic or carcinogenic risk to humans. We conclude that if the home\u27s location wasn\u27t carefully considered, heavy metal exposure could increase health risks. Following the findings, we recommend more comprehensive and adequate measures should be made to reduce the impacts and cancer risk associated with indoor floor dust ingestion in both children and adults. Adults should be informed of associated risks to safeguard their health and children health

Occupational Exposure to Blood and Bodily Fluids among Health Care Workers

Health Care workers (HCWS) must handle with a variety of occupational exposure. One significant exposure for HCWS in a hospital and Emergency Medical Services (EMS) providers in out of hospital expose to blood and bodily fluids during the performance of their duties , resulting in concerns regarding transmission of blood-borne pathogens such as hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV). To manage the unpleasant effects of exposure to blood and bodily fluids, HCWs including EMS providers and other health care occupations must completely comply with standard precautions (SPs) recommendations and to attend continuing education regarding blood borne pathogens. In this study, the extent of knowledge, consistency, and practices of SPs were assessed and characteristics of rural and urban EMS providers that predicted lacking compliance with SPs were explored. In addition, this study assessed knowledge of EMS providers regarding Needle stick injuries. Finally, this study evaluated blood and bodily fluids exposure incidents among HWCs in hospital in general