2,732 research outputs found

    Probing of the Kondo peak by the impurity charge measurement

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    We consider the real-time dynamics of the Kondo system after the local probe of the charge state of the magnetic impurity. Using the exactly solvable infinite-degeneracy Anderson model we find explicitly the evolution of the impurity charge after the measurement.Comment: 4 pages, 1 eps figure, revte

    First Application of Pulse-Shape Analysis to Silicon Micro-Strip Detectors

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    The method of pulse-shape analysis (PSA) for particle identification (PID) was applied to a double-sided silicon strip detector (DSSD) with a strip pitch of 300 \{mu}m. We present the results of test measurements with particles from the reactions of a 70 MeV 12C beam impinging on a mylar target. Good separation between protons and alpha particles down to 3 MeV has been obtained when excluding the interstrip events of the DSSD from the analysis.Comment: 7 pages, 6 figures, submitted to Nuclear Inst. and Methods in Physics Research

    The effect of neoadjuvant therapy on PD-L1 expression and CD8+lymphocyte density in non-small cell lung cancer.

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    PD-L1 expression is the routine clinical biomarker for the selection of patients to receive immunotherapy in non-small cell lung cancer (NSCLC). However, the application and best timing of immunotherapy in the resectable setting is still under investigation. We aimed to study the effect of chemotherapy on PD-L1 expression and tumor infiltrating lymphocytes (TILs), which is to date still poorly understood. Our retrospective, single-centre neoadjuvant cohort comprised 96 consecutive patients with NSCLC resected 2000-2016 after neoadjuvant therapy, including paired diagnostic chemo-naïve specimens in 53 cases. A biologically matched surgical cohort of 114 primary resected cases was included. PD-L1 expression, CD8 + TILs density and tertiary lymphoid structures were assessed on whole slides and correlated with clinico-pathological characteristics and survival. Seven/53 and 12/53 cases had lower respectively higher PD-L1 expressions after neoadjuvant therapy. Most cases (n = 34) showed no changes in PD-L1 expression, the majority of these harboring PD-L1 < 1% in both samples (21/34 [61.8%]). Although CD8 + TILs density was significantly higher after chemotherapy (p = 0.031) in resections compared to diagnostic biopsies, this might be due to sampling and statistical bias. No difference in PD-L1 expression or CD8 + TILs density was detected when comparing the neoadjuvant and surgical cohort. In univariable analyses, higher CD8 + TILs density, higher numbers of tertiary lymphoid structures but not PD-L1 expression were significantly associated with longer survival. Increased PD-L1 expression after neoadjuvant chemotherapy was not significantly associated with shorter 5-year survival, but the number of cases was very low. In multivariable analysis, only pT category and age remained independent prognostic factors. In summary, PD-L1 expression was mostly unchanged after neoadjuvant chemotherapy compared to diagnostic biopsies. The sample size of cases with changed PD-L1 expression was too small to draw conclusions on any prognostic value

    What is the Thouless Energy for Ballistic Systems?

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    The Thouless energy, \Ec characterizes numerous quantities associated with sensitivity to boundary conditions in diffusive mesoscopic conductors. What happens to these quantities if the disorder strength is decreased and a transition to the ballistic regime takes place? In the present analysis we refute the intuitively plausible assumption that \Ec loses its meaning as an inverse diffusion time through the system at hand, and generally disorder independent scales take over. Instead we find that a variety of (thermodynamic) observables are still characterized by the Thouless energy.Comment: 4 pages REVTEX, uuencoded file. To appear in Physical Review Letter

    Persistent Currents in Quantum Chaotic Systems

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    The persistent current of ballistic chaotic billiards is considered with the help of the Gutzwiller trace formula. We derive the semiclassical formula of a typical persistent current ItypI^{typ} for a single billiard and an average persistent current for an ensemble of billiards at finite temperature. These formulas are used to show that the persistent current for chaotic billiards is much smaller than that for integrable ones. The persistent currents in the ballistic regime therefore become an experimental tool to search for the quantum signature of classical chaotic and regular dynamics.Comment: 4 pages (RevTex), to appear in Phys. Rev. B, No.59, 12256-12259 (1999

    Phi_0 - Periodic Aharonov-Bohm Oscillations Survive Ensemble Averaging

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    We have demonstrated that Phi_0 periodic Aharonov--Bohm oscillations measured in a ensemble of rings may survive after ensemble averaging procedure. The central point is the difference between the preparation stage of the ensemble and the subsequent measurement stage. The robustness of the effect under finite temperature and non--zero charging energy of rings is discussed.Comment: 11 pages, 2 figures, RevTex 3.0,WIS-93/84/Aug.-P

    Analyzing the success of T-matrix diagrammatic theories in representing a modified Hubbard model

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    We present a systematic study of various forms of renormalization that can be applied in the calculation of the self-energy of the Hubbard model within the T-matrix approximation. We compare the exact solutions of the attractive and repulsive Hubbard models, for linear chains of lengths up to eight sites, with all possible taxonomies of the T-matrix approximation. For the attractive Hubbard model, the success of a minimally self-consistent theory found earlier in the atomic limit (Phys. Rev. B 71, 155111 (2005)) is not maintained for finite clusters unless one is in the very strong correlation limit. For the repulsive model, in the weak correlation limit at low electronic densities -- that is, where one would expect a self-consistent T-matrix theory to be adequate -- we find the fully renormalized theory to be most successful. In our studies we employ a modified Hubbard interaction that eliminates all Hartree diagrams, an idea which was proposed earlier (Phys. Rev. B 63, 035104 (2000)).Comment: Includes modified discussion of 1st-order phase transition. Accepted for publication in J. Phys.: Condensed Matte

    Two interacting quasiparticles above the Fermi sea

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    We study numerically the interaction and disorder effects for two quasiparticles in two and three dimensions. The dependence of the interaction-induced Breit-Wigner width on the excitation energy above the Fermi level, the disorder strength and the system size is determined. A regime is found where the width is practically independent of the excitation energy. The results allow to estimate the two quasiparticle mobility edge.Comment: revtex, 4 pages, 4 figure

    Berry phase and persistent current in disordered mesoscopic rings

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    A novel quantum interference effect in disordered quasi-one-dimensional rings in the inhomogeneous magnetic field is reported. We calculate the canonical disorder averaged persistent current using the diagrammatic perturbation theory. It is shown that within the adiabatic regime the average current oscillates as a function of the geometric flux which is related to the Berry phase and the period becomes half the value of the case of a single one-dimensional ring. We also discuss the magnetic dephasing effect on the averaged current.Comment: 6 pages, RevTeX, 2 figures. To appear in Phys. Rev. B Rapid Communications Vol.60 No.12 (1999

    The interplay between electron-electron interactions and impurities in one-dimensional rings

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    The persistent current and charge stiffness of a one-dimensional Luttinger liquid on a ring threaded by a magnetic flux are calculated by Monte Carlo simulation. By changing the random impurity potential strength and the electron-electron interaction, we see a crossover behavior between weak and strong impurity limits. For weak impurity potentials, interactions enhance impurity effects, that is, interactions decrease the current and the stiffness. On the other hand, interactions tend to screen impurities when the impurity potential is strong. Temperature dependence of the persistent current and the charge stiffness shows a peak at a characteristic temperature, consistent with a recent single impurity study.Comment: 4 pages (ReVTeX3.0) + 3 figures (in uuencoded postscript format) appended in the end of the fil
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