337 research outputs found

    Process, politics and participation: Experiences with strategies for local capacity building

    Get PDF
    This seminar report is about the Sinpa programme. Therefore a brief explanation of the objectives and project history is provided in this chapter to serve as background information for what is to follow. Objectives of the SINPA programme The overall goal of the SINPA programme is to help implement National Plans of Action and the Habitat Agenda by building sustainable local capacity for effective planning and management of urban development. More concretely, the programme aims to assist local government and its partners in capacity building for action in the broad areas of housing, local environmental management and participative planning processes and partnerships relating to these subjects. It especially focuses on the challenges of improving access to services and better environment for the urban poor, with particular regard to gender issues. The broad objectives of the programme are: • to stimulate the development of local capacity building strategies; • to stimulate selected local and national capacity building institutions to become more responsive to needs and to enhance quality of performance; • to stimulate urban stakeholders to learn from relevant past and ongoing experience with implementing urban development policy and projects; • to improve understanding and communication of experience relevant to needs of city development in the linked areas of housing, environmental management, participative planning and partnerships. SINPA aims to achieve these objectives by helping to bring local development partners and capacity building institutions together so as to improve capacity in a manner that will be sustainable locally. The programme is structured in a core programme, which provides co-ordination, information inputs, linkage and dissemination, and three country programmes that are developed locally in response to local issues. The country programmes are being implemented in secondary cities in Bangladesh, Bolivia and Zambia. The SINPA programme adopts a proces

    Driving Performance in Patients With Idiopathic Cervical Dystonia; A Driving Simulator Pilot Study

    Get PDF
    Objective: To explore driving performance and driving safety in patients with cervical dystonia (CD) on a simulated lane tracking, intersections and highway ride and to compare it to healthy controls. Design: This study was performed as an explorative between groups comparison. Participants: Ten CD patients with idiopathic CD, 30 years or older, stable on botulinum toxin treatment for over a year, holding a valid driver's license and being an active driver were compared with 10 healthy controls, matched for age and gender. Main outcome measures: Driving performance and safety, measured by various outcomes from the simulator, such as the standard deviation of the lateral position on the road, rule violations, percentage of line crossings, gap distance, and number of collisions. Fatigue and driving effort were measured with the Borg CR-10 scale and self-perceived fitness to drive was assessed with Fitness to Drive Screening. Results: Except for a higher percentage of line crossings on the right side of the road by controls (median percentage 2.30, range 0.00-37.00 vs. 0.00, range 0.00-9.20, p = 0.043), no differences were found in driving performance and driving safety during the simulator rides. Fatigue levels were significantly higher in CD patients just before (p = 0.005) and after (p = 0.033) the lane tracking ride (patients median fatigue levels before 1.5 (range 0.00-6.00) and after 1.5 (range 0.00-7.00) vs. controls median fatigue levels before and after 0.00 (no range). No significant differences were found on self-perceived fitness to drive. Conclusion: In patients with CD there were no indications that driving performance or driving safety were significant different from healthy controls in a simulator. Patients reported higher levels of fatigue both before and after driving compared to controls in accordance with the non-motor symptoms known in CD

    Test Arrangement of Small-scale Shear Tests of Composite Slabs

    Get PDF
    AbstractComposite slab consists of the layer of concrete above the trapezoidal sheeting. The sheeting serves as a lost formwork as well as a tension bearing member after the hardening of concrete. The interaction between the sheeting and the concrete is necessary for composite action and can be ensured by prepressed embossments in the sheeting. According to nowadays codes, full scale bending tests are required in the design of the new sheeting of this type of composite slabs. An alternative longitudinal shear tests of a small part of the slab have already been derived by many authors. However, the testing arrangement is not unified. The results of the shear tests can be influenced by the magnitude and the way of application of the clamping force, the loading speed, the interface conditions and others. This paper presents a proposal of the testing arrangement and the recommendations for the testing procedure of small-scale shear tests. The recommendations are posted based on the results of several series of performed laboratory tests

    Regulacija puta razgradnje pentoza s pomoću gena izoliranih iz plijesni Aspergillus niger

    Get PDF
    The aim of this study was to obtain a better understanding of the pentose catabolism in Aspergillus niger and the regulatory systems that affect it. To this end, we have cloned and characterised the genes encoding A. niger L-arabitol dehydrogenase (ladA) and xylitol dehydrogenase (xdhA), and compared the regulation of these genes to other genes of the pentose catabolic pathway. This demonstrated that activation of the pathway depends on two transcriptional regulators, the xylanolytic activator (XlnR) and an unidentified L-arabinose specific regulator (AraR). These two regulators affect those genes of the pentose catabolic pathway that are related to catabolic conversion of their corresponding inducers (D-xylose and L-arabinose, respectively).Istraživanje je provedeno radi boljeg razumijevanja puta razgradnje pentoza plijesni Aspergillus niger i regulacijskih sustava koji na njega utječu. Klonirani su i karakterizirani geni koji kodiraju L-arabitol dehidrogenazu (ladA) i ksilitol dehidrogenazu (xdhA) plijesni A. niger, te uspoređeni s ostalim genima koji reguliraju put razgradnje pentoza. Otkriveno je da aktivacija puta razgradnje ovisi o dva regulatora transkripcije gena, tj. aktivatoru razgradnje D-ksiloze (XlnR) i regulatoru ekspresije gena pri razgradnji L-arabinoze (AraR)

    Influenza vaccination of healthcare workers in acute-care hospitals: a case-control study of its effect on hospital-acquired influenza among patients

    Get PDF
    <p>Abstract</p> <p>Background</p> <p>In acute-care hospitals, no evidence of a protective effect of healthcare worker (HCW) vaccination on hospital-acquired influenza (HAI) in patients has been documented. Our study objective was to ascertain the effectiveness of influenza vaccination of HCW on HAI among patients.</p> <p>Methods</p> <p>A nested case-control investigation was implemented in a prospective surveillance study of influenza-like illness (ILI) in a tertiary acute-care university hospital. Cases were patients with virologically-confirmed influenza occurring ≥ 72 h after admission, and controls were patients with ILI presenting during hospitalisation with negative influenza results after nasal swab testing. Four controls per case, matched per influenza season (2004-05, 2005-06 and 2006-07), were randomly selected. Univariate and multivariate conditional logistic regression models were fitted to assess factors associated with HAI among patients.</p> <p>Results</p> <p>In total, among 55 patients analysed, 11 (20%) had laboratory-confirmed HAI. The median HCW vaccination rate in the units was 36%. The median proportion of vaccinated HCW in these units was 11.5% for cases vs. 36.1% for the controls (<it>P </it>= 0.11); 2 (20%) cases and 21 (48%) controls were vaccinated against influenza in the current season (<it>P </it>= 0.16). The proportion of ≥ 35% vaccinated HCW in short-stay units appeared to protect against HAI among patients (odds ratio = 0.07; 95% confidence interval 0.005-0.98), independently of patient age, influenza season and potential influenza source in the units.</p> <p>Conclusions</p> <p>Our observational study indicates a shielding effect of more than 35% of vaccinated HCW on HAI among patients in acute-care units. Investigations, such as controlled clinical trials, are needed to validate the benefits of HCW vaccination on HAI incidence in patients.</p
    corecore