619 research outputs found
ΠΡΠΎΠ±Π»ΠΈΠ²ΠΎΡΡΡ ΡΠΌΡΠ½ΠΎ-Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΡΠ° ΠΌΡΠΊΡΠΎΠ±ΡΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΡ Ρ ΠΆΡΠ½ΠΎΠΊ Π· ΡΡΠ·Π½ΠΈΠΌΠΈ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΡΡΠ½ΠΈΠΌΠΈ ΡΠΎΡΠΌΠ°ΠΌΠΈ ΠΏΠΎΠ»ΡΠΏΡΠ² Π΅Π½Π΄ΠΎΠΌΠ΅ΡΡΡΡ
ΠΠ±ΡΠ»Π΅Π΄ΠΎΠ²Π°Π½ΠΎ 58 ΠΆΠ΅Π½ΡΠΈΠ½ Ρ ΠΏΠΎΠ»ΠΈΠΏΠ°ΠΌΠΈ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ. ΠΡΡΠ²Π»Π΅Π½Ρ ΠΎΡΠΎΠ±Π΅Π½Π½ΠΎΡΡΠΈ ΠΌΠΈΠΊΡΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ
ΠΏΠ΅ΠΉΠ·Π°ΠΆΠ°, Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠ³ΠΎ ΡΡΠ°ΡΡΡΠ° Π² Π·Π°Π²ΠΈΡΠΈΠΌΠΎΡΡΠΈ ΠΎΡ ΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΈΡ
ΡΠΎΡΠΌ ΠΏΠΎΠ»ΠΈΠΏΠΎΠ² ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ.
ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½Π½ΡΠΉ Π°Π½Π°Π»ΠΈΠ· ΠΏΠΎΠ·Π²ΠΎΠ»ΠΈΠ» Π²ΡΠ΄Π΅Π»ΠΈΡΡ Π³ΡΡΠΏΠΏΡ ΡΠΈΡΠΊΠ° ΠΏΠΎ ΡΠ°Π·Π²ΠΈΡΠΈΡ ΠΏΠΎΠ»ΠΈΠΏΠΎΠ² ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ. ΠΏΠΎΠΊΠ°Π·Π°Π½ΠΎ, ΡΡΠΎ
ΠΏΠΎΠ»ΠΈΠΏ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ ΡΠ»Π΅Π΄ΡΠ΅Ρ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡ Π½Π΅ ΠΊΠ°ΠΊ ΠΌΠ΅ΡΡΠ½ΡΠΉ ΠΏΡΠΎΡΠ΅ΡΡ, Π° ΠΊΠ°ΠΊ ΡΠ΅Π°ΠΊΡΠΈΡ ΡΠ½Π΄ΠΎΠΌΠ΅ΡΡΠΈΡ Π² ΠΎΡΠ²Π΅Ρ Π½Π°
ΠΏΠΎΠ²ΡΠ΅ΠΆΠ΄Π΅Π½ΠΈΠ΅ Π³ΠΎΡΠΌΠΎΠ½Π°Π»ΡΠ½ΠΎΠ³ΠΎ ΠΈ ΠΈΠΌΠΌΡΠ½Π½ΠΎΠ³ΠΎ Π³ΠΎΠΌΠ΅ΠΎΡΡΠ°Π·Π°, ΡΡΠΎ Π½Π΅ΠΎΠ±Ρ
ΠΎΠ΄ΠΈΠΌΠΎ ΡΡΠΈΡΡΠ²Π°ΡΡ ΠΏΡΠΈ Π²ΡΠ±ΠΎΡΠ΅ Π»Π΅ΡΠ΅Π½ΠΈΡ
Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠ°ΡΠΎΠ»ΠΎΠ³ΠΈΠΈ58 women with endometrial polyps were investigated. Specific microflora and hormonal and immune status
depending on the morphological forms of endometrial polyps were found. The analysis performed allowed to
allocate risk groups according to development of endometrial polyp. It was shown that endometrial polyp shall be
considered as endometrial reaction in response to hormonal and immune homeostasis disorder, rather than local
process. This should be borne in mind when choosing treatment for this patholog
The Impact of Socioeconomic Status, Surgical Resection and Type of Hospital on Survival in Patients with Pancreatic Cancer:A Population-Based Study in The Netherlands
The influence of socioeconomic inequalities in pancreatic cancer patients and especially its effect in patients who had a resection is not known. Hospital type in which resection is performed might also influence outcome. Patients diagnosed with pancreatic cancer from 1989 to 2011 (n = 34,757) were selected from the population-based Netherlands Cancer Registry. Postal code was used to determine SES. Multivariable survival analyses using Cox regression were conducted to discriminate independent risk factors for death. Patients living in a high SES neighborhood more often underwent resection and more often were operated in a university hospital. After adjustment for clinicopathological factors, risk of dying was increased independently for patients with intermediate and low SES compared to patients with high SES. After resection, no survival difference was found among patients in the three SES groups. However, survival was better for patients treated in university hospitals compared to patients treated in non-university hospitals. Low SES was an independent risk factor for poor survival in patients with pancreatic cancer. SES was not an adverse risk factor after resection. Resection in non-university hospitals was associated with a worse prognosis.</p
Age and prognosis in patients with pancreatic cancer:a population-based study
BACKGROUND: The diagnosis of pancreatic ductal adenocarcinoma (PDAC) has an enormous impact on patients, and even more so if they are of younger age. It is unclear how their treatment and outcome compare to older patients. This study compares clinicopathological characteristics and overall survival (OS) of PDAC patients aged <60βyears to older PDAC patients. METHOD: This is a retrospective, population-based cohort study using Netherlands Cancer Registry data of patients diagnosed with PDAC (1 January 2015-31 December 2018). Kaplan-Meier curves and Cox proportional hazards models were used to assess OS. RESULTS: Overall, 10,298 patients were included, of whom 1551 (15%) were <60βyears. Patients <60βyears were more often male, had better performance status, less comorbidities and less stage I disease, and more often received anticancer treatment (67 vs. 33%, pβ<β0.001) than older patients. Patients <60βyears underwent resection of the tumour more often (22 vs. 14%pβ<β0.001), more often received chemotherapy, and had a better median OS (6.9 vs. 3.3βmonths, pβ<β0.001) compared to older patients. No differences in median OS were demonstrated between both age groups of patients who underwent resection (19.7 vs. 19.4βmonths, pβ=β0.123), received chemotherapy alone (7.8 vs. 8.5βmonths, pβ=β0.191), or received no anticancer treatment (1.8 vs. 1.9βmonths, pβ=β0.600). Patients <60βyears with stage-IV disease receiving chemotherapy had a somewhat better OS (7.5 vs. 6.3βmonths, pβ=β0.026). CONCLUSION: Patients with PDAC <60βyears more often underwent resection despite less stage I disease and had superior OS. Stratified for treatment, however, survival was largely similar
Drought, mutualism breakdown, and landscape-scale degradation of seagrass beds
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Effect of centralization and regionalization of pancreatic surgery on resection rates and survival
Contains fulltext :
236824.pdf (Publisherβs version ) (Closed access
Toward Reliable Uptake Metrics in Large Vessel Vasculitis Studies
The aim of this study is to investigate the influence of sex, age, fat mass, fasting blood glucose level (FBGL), and estimated glomerular filtration rate (eGFR) on blood pool activity in patients with large vessel vasculitis (LVV). Blood pool activity was measured in the superior caval vein using mean, maximum, and peak standardized uptake values corrected for body weight (SUVs) and lean body mass (SULs) in 41 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) scans of LVV patients. Sex influence on the blood pool activity was assessed with t-tests, while linear correlation analyses were used for age, fat mass, FBGL, and eGFR. Significantly higher SUVs were found in women compared with men, whereas SULs were similar between sexes. In addition, higher fat mass was associated with increased SUVs (r = 0.56 to 0.65; all p p > 0.05). Lower eGFR was associated with a higher FDG blood pool activity for all uptake values. In FDG-PET/CT studies with LVV patients, we recommend using SUL over SUV, while caution is advised in interpreting SUV and SUL measures when patients have impaired kidney function
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