37 research outputs found
Transversality of the logarithmic divergences in the Classical Finite Temperature SU(N) Self-Energy
We show that the logarithmic divergences that appear in the classical
approximation of the finite temperature SU(N) self-energy are transverse. We
use the Ward identities in linear gauges and the fact that the superficial
degree of divergence d of a classical diagram only depends on the number of
loops l via d=2-l. We comment on the relevance of this result to the
construction of a low-energy effective theory beyond HTLs.Comment: 5 pages, 1 figure, REVTE
Temperature Dependence of the QCD Coupling
We present a one-loop calculation of a gauge invariant QCD beta function.
Using both momentum and temperature renormalization group equations we
investigate the running coupling in the magnetic sector as a function of
temperature and momentum scale. At fixed momentum scale we find that, in
contrast to or QED, high-temperature QCD is strongly coupled,
even after renormalization group improvement. However, if the momentum scale is
changed simultaneously with temperature in a specified manner, the coupling
decreases. We also point out in what regime dimensional reduction occurs. Both
the cases smaller and larger than are discussed.Comment: 10 pages, LaTeX (5 postscript figures available),
ITFA-93-11,THU-93/0
The Semi-Classical Relativistic Darwin Potential for Spinning Particles in the Rest-Frame Instant Form: 2-Body Bound States with Spin 1/2 Constituents
In the semiclassical approximation of Grassmann-valued electric charges for
regularizing Coulomb self-energies, we extract the unique
acceleration-independent interaction hidden in any Lienard-Wiechert solution
for the system of N positive-energy spinning particles plus the electromagnetic
field in the radiation gauge of the rest-frame instant form. With the help of a
semiclassical Foldy-Wouthuysen transformation, this allows us to find the
relativistic semiclassical Darwin potential. In the 2-body case the
quantization of the lowest order reproduces exactly the results from the
reduction of the Bethe-Salpeter equation.Comment: 102 pages, revtex fil
Physicochemical and biological characterization of 1E10 Anti-Idiotype vaccine
<p>Abstract</p> <p>Background</p> <p>1E10 monoclonal antibody is a murine anti-idiotypic antibody that mimics N-glycolyl-GM3 gangliosides. This antibody has been tested as an anti-idiotypic cancer vaccine, adjuvated in Al(OH)<sub>3</sub>, in several clinical trials for melanoma, breast, and lung cancer. During early clinical development this mAb was obtained <it>in vivo </it>from mice ascites fluid. Currently, the production process of 1E10 is being transferred from the <it>in vivo </it>to a bioreactor-based method.</p> <p>Results</p> <p>Here, we present a comprehensive molecular and immunological characterization of 1E10 produced by the two different production processes in order to determine the impact of the manufacturing process in vaccine performance. We observed differences in glycosylation pattern, charge heterogeneity and structural stability between <it>in vivo</it>-produced 1E10 and bioreactor-obtained 1E10. Interestingly, these modifications had no significant impact on the immune responses elicited in two different animal models.</p> <p>Conclusions</p> <p>Changes in 1E10 primary structure like glycosylation; asparagine deamidation and oxidation affected 1E10 structural stability but did not affect the immune response elicited in mice and chickens when compared to 1E10 produced in mice.</p