Cognitive deficits following stroke in the basal ganglia

Objective. To examine the effect of a stroke in the basal ganglia on cognitive functioning. Design: As part of a larger prospective study on the neuropsychological and psychosocial consequences of stroke, 12 patients with a stroke confined to the basal ganglia were examined. Setting: The patients were assessed in one of the three participating hospitals. Subjects: The results of 12 patients with a stroke in the basal ganglia (mean age 55 years), were compared to 24 controls (mean age 54.3 years). Main outcome measures: Different aspects of memory, attention and concentration, visuospatial and visuoconstructive functions, language and arithmetic were assessed using neuropsychological tests. Results: The data show a significant abnormality in cognitive functioning on ail cognitive domains. Conclusions: The results stress the notion that subcortical damage may lead to substantial neuropsychological disorders and have clear implications for neurological rehabilitation