The impact of concepts of minjung on thought and culture in Korea during the period of authoritarian politics (1948-1987)

This thesis is a study of concepts of the Korean masses. The identity of the Korean masses is multi-faceted. They have been referred to as the 'minjung' and characterised in the 1970s as 'the subject of history’(yoksa-ui chuch'e) and as the 'oppressed people' who struggle against the political, economic and cultural oppression of the ruling power. This min jung struggle ultimately created a new opportunity for democracy in 1987

Not your average biker; Criminal careers of members of Dutch outlaw motorcycle gangs

Based on criminal career data of a sample of 601 police-identified outlaw motorcycle gang members and an age-matched comparison group of 300 non-gang affiliated motorcycle owners, the current analysis examines various dimensions of the criminal careers of outlaw bikers, including participation, onset, frequency, and crime mix. Results show that Dutch outlaw bikers are more often convicted than the average Dutch motorcyclist, and that these convictions not only pertain to minor offenses but also to serious and violent crimes. We find that outlaw bikers’ criminal careers differ from that of the average Dutch motorcyclist already during the juvenile and early adult years, but also – and more so – during the adult years. These results fit the enhancement hypothesis of gang membership and suggest that both selection of crime prone individuals in outlaw motorcycle gangs and facilitation of criminal behavior whilst in the gang are taking place.Criminal Justice: Legitimacy, accountability, and effectivit

Optical Detection of Preneoplastic Lesions of the Central Airways

Current routine diagnosis of premalignant lesions of the central airways is hampered due to a limited sensitivity (white light bronchoscopy) and resolution (computer tomography (CT), positron emission tomography (PET)) of currently used techniques. To improve the detection of these subtle mucosal abnormalities, novel optical imaging bronchoscopic techniques have been developed over the past decade. In this review we highlight the technological developments in the field of endoscopic imaging, and describe their advantages and disadvantages in clinical use

Greater Expectations?

Physically Unclonable Functions (PUFs) are key tools in the construction of lightweight authentication and key exchange protocols. So far, all existing PUF-based authentication protocols follow the same paradigm: A resource-constrained prover, holding a PUF, wants to authenticate to a resource-rich verifier, who has access to a database of pre-measured PUF challenge-response pairs (CRPs). In this paper we consider application scenarios where all previous PUF-based authentication schemes fail to work: The verifier is resource-constrained (and holds a PUF), while the prover is resource-rich (and holds a CRP-database). We construct the first and efficient PUF-based authentication protocol for this setting, which we call converse PUF-based authentication. We provide an extensive security analysis against passive adversaries, show that a minor modification also allows for authenticated key exchange and propose a concrete instantiation using controlled Arbiter PUFs

Dry reforming of methane over single-atom Rh/Al₂O₃ catalysts prepared by exsolution

Single-atom catalysts often show exceptionally high performance per metal loading. However, the isolated atom sites tend to agglomerate during preparation and/or high-temperature reaction. Here we show that in the case of Rh/Al2O3 this deactivation can be prevented by dissolution/exsolution of metal atoms into/from the support. We design and synthesise a series of single-atom catalysts, characterise them and study the impact of exsolution in the dry reforming of methane at 700-900 °C. The catalysts' performance increases with increasing reaction time, as the rhodium atoms migrate from the subsurface to the surface. Although the oxidation state of rhodium changes from Rh(iii) to Rh(ii) or Rh(0) during catalysis, atom migration is the main factor affecting catalyst performance. The implications of these results for preparing real-life catalysts are discussed.</p

Erratum to: Circulating tumor DNA as a biomarker for monitoring early treatment responses of patients with advanced lung adenocarcinoma receiving immune checkpoint inhibitors.

The following error appeared in Section 3.5 in Ref. [1]. Instead of ‘Progressive disease-L1 expression data were available for 87 patients’, the text should read ‘PD-L1 expression data were available for 87 patients’. We apologize for this error.</p

UPDATE OF THE NEAC MODAL-SPLIT MODEL

INTRODUCTION The NEAC model and information system consists of models and methods for constructing databases describing the current freight transport flows and for developing forecasts of future freight transport flows. NEAC describes all intra-and inter-regional freight transport in Western and Eastern Europe by transport mode and by commodity type. Results are expressed in total weight of the goods. In NEAC, a classical four step modelling approach is used. This approach consists of the following steps: 1. Trade and transport generation; 2. Regional distribution; 3. Mode choice; 4. Route choice/assignment. The third step, the model for mode choice, is the subject of this paper. In 2005, NEA carried out a research project to update the NEAC modal-split model. This paper presents the assumptions, highlights the results and also mentions the differences between the previous and the new version. The goal of the research project was to develop a model that could replace the outdated modal-split model. As well as the calibration of updated parameters, the aim was to also incorporate the transport mode short sea in the model. To achieve this NEA has developed and calibrated a completely new model. An analysis of the effects of the new NEAC modal-split model on forecasts of main European transport flows is presented. The modal-split model for freight transport within the TRANS-TOOLS research project 1 is based on the new NEAC model. The goal of TRANS-TOOLS, which is co-funded by the European Commission (DG-TREN) under the 6th Framework Programme for Research and Development, is to produce European transport network models to overcome the shortcomings of current models. THE NEAC MODEL AND INFORMATION SYSTEM The NEAC model and information system is the collection of the databases and models which are described below. These modules are linked through their input and output. The basis of the system is the NEAC base year database. Several national and international trade and transport data sources are the input for the construction of the database. Several techniques are used to combine different data sources into one database. The idea behind the construction of the database is that trade flows determine transport flows. A trade flow is the economic activity between a production region and a consumption region. A transport flow is the shipment of commodities from a ©Association for European Transport and contributors 200

Gene Expression-Based Classification of Non-Small Cell Lung Carcinomas and Survival Prediction

Background: Current clinical therapy of non-small cell lung cancer depends on histo-pathological classification. This approach poorly predicts clinical outcome for individual patients. Gene expression profiling holds promise to improve clinical stratification, thus paving the way for individualized therapy. Methodology and Principal Findings: A genome-wide gene expression analysis was performed on a cohort of 91 patients. We used 91 tumor- and 65 adjacent normal lung tissue samples. We defined sets of predictor genes (probe sets) with the expression profiles. The power of predictor genes was evaluated using an independent cohort of 96 non-small cell lung cancer- and 6 normal lung samples. We identified a tumor signature of 5 genes that aggregates the 156 tumor and normal samples into the expected groups. We also identified a histology signature of 75 genes, which classifies the samples in the major histological subtypes of non-small cell lung cancer. Correlation analysis identified 17 genes which showed the best association with post-surgery survival time. This signature was used for stratification of all patients in two risk groups. Kaplan-Meier survival curves show that the two groups display a significant difference in post-surgery survival time (p = 5.6E-6). The performance of the signatures was validated using a patient cohort of similar size (Duke University, n = 96). Compared to previously published prognostic signatures for NSCLC, the 17 gene signature performed well on these two cohorts

The impact of loco-regional recurrences on metastatic progression in early-stage breast cancer: a multistate model

To study whether the effects of prognostic factors associated with the occurrence of distant metastases (DM) at primary diagnosis change after the incidence of loco-regional recurrences (LRR) among women treated for invasive stage I or II breast cancer. The study population consisted of 3,601 women, enrolled in EORTC trials 10801, 10854, or 10902 treated for early-stage breast cancer. Data were analysed in a multivariate, multistate model by using multivariate Cox regression models, including a state-dependent covariate. The presence of a LRR in itself is a significant prognostic risk factor (HR: 3.64; 95%-CI: 2.02-6.5) for the occurrence of DM. Main prognostic risk factors for a DM are young age at diagnosis (</=40: HR: 1.79; 95%-CI: 1.28-2.51), larger tumour size (HR: 1.58; 95%-CI: 1.35-1.84) and node positivity (HR: 2.00; 95%-CI: 1.74-2.30). Adjuvant chemotherapy is protective for a DM (HR: 0.66; 95%-CI: 0.55-0.80). After the occurrence of a LRR the latter protective effect has disappeared (P = 0.009). The presence of LRR in itself is a significant risk factor for DM. For patients who are at risk of developing LRR, effective local control should be the main target of therapy