The total synthesis of 1-oxygenated eudesmane sesquiterpenes : (±) dihydroreynosin and (±) 1-oxocostic acid

The total synthesis of (±) dihydroreynosin 1 and of (±) 1-oxocostic acid 2 (R = H) are illustrative examples for a short entry into 1-oxygenated eudesmanes via an easily accessible key intermediate 7

The total synthesis of 1-oxygenated eudesmanolides

A route towards I-oxygenated eudesmanolides, via a (2+2) photocycloaddition reaction for constructing the decalin framework is described. The following natural substances have been synthesized. (=)-dihydroreynosin (1), (±)-1- oxo-dihydronmagnolialide (2), (±)-maritimin (3), (±)-dihydromagnolialide (4), (±)-magnolialide (5), (±)-dihydrosantamarine (6). Also a synthesis of (±)--santonin (7) is presented

Diterpene total synthesis : an improved stereoselective route to (±)-3,4,5,5a,7,8,8aα,8bα-octahydro-2aα,5aβ-dimethyl-2H-naphto-|1,8-bc|furan-2,6-(2aH)-dione

The synthesis of the title compound 13, via a photochemical (π2 + π2) annellation procedure and a highly stereo-selective hydrocyanation reaction, is described

General and Versatile Entry to 4,5-Fused Polycyclic Imidazolones Systems. Use of the Tandem Transposition/π-Cyclization of N -Acyliminium Species

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Use of the Newly Heterocyclization/Double Transposition/Isomerisation of N-acyliminium ion Cascade to Access Tricyclic Thiolactams

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General and Versatile Entry to Polycyclic Imidazolidinones: Use of N-acyliminium Chemistry in Domino Process

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The 52 nd International Conference on Medicinal Chemistry (RICT 2016) of the French Medicinal Chemistry Society (SCT) Held in Caen (Normandy)

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Heterocyclization-Transposition-Isomerisation of N-acyliminium ion. Domino Process to Accede New Tricyclic Thiolactams

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Synthesis of potential mTOR inhibitors

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Interfacing Chemical Biology and Drug Discovery: Report from the 50th International Conference on Medicinal Chemistry of the SCT (French Medicinal Chemistry Society), July 2–4, 2014, Rouen, France

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