Infectious bronchitis virus infections of chickens in Belgium : an epidemiological survey

Between April 2012 and July 2015, cloacal and/or tracheal swab samples were collected from four hundred and twenty-four Belgian chicken broiler, breeder and layer flocks. All flocks were kept for production purposes and presented clinical signs suggestive of an infectious bronchitis virus (IBV) infection. The samples were analyzed by real-time polymerase chain reaction (RT-qPCR) to detect the presence of ribonucleic acid (RNA) of IBV. When positive, approximately four hundred base pairs (bp) encoding for the hypervariable region of the IBV S1 protein were sequenced. Sequencing results, cycle threshold (Ct) values and vaccination history were used as criteria to try and distinguish vaccine strains from field strains. Of all samples examined, 22.4% was negative. In 16.4% of the samples that did contain RNA from IBV, the genotype could not be determined. In most cases, this was due to the recovery of RNA quantities below the lower limit of detection of the sequencing PCR. The remaining positive submissions predominantly revealed RNA from IBV strains that belonged to the 4/91-793B (46.8%), D388-QX (25.2%), D274-D207 (5.8%) and Massachusetts (4.0%) genotypes. Estimations indicated that approximately 58%, 11%, 37% and 46% of these detections, respectively, were vaccine strains. Infections with types CK/CH/Guandong/Xindadi/0903, Ukr/27/2011, NGA/295/2006 and Q1 were observed sporadically. The results indicate that IBV infections are highly prevalent in Belgian chickens and that at least eight different IBV types were circulating during the monitored period. This underlines the necessity of providing flocks with a strong and broad protective immunity against IBV

Lifelong personal health data and application software via virtual machines in the cloud

Personal Health Records (PHRs) should remain the lifelong property of patients, who should be able to show them conveniently and securely to selected caregivers and institutions. In this paper, we present MyPHRMachines, a cloud-based PHR system taking a radically new architectural solution to health record portability. In MyPHRMachines, health-related data and the application software to view and/or analyze it are separately deployed in the PHR system. After uploading their medical data to MyPHRMachines, patients can access them again from remote virtual machines that contain the right software to visualize and analyze them without any need for conversion. Patients can share their remote virtual machine session with selected caregivers, who will need only a Web browser to access the pre-loaded fragments of their lifelong PHR. We discuss a prototype of MyPHRMachines applied to two use cases, i.e., radiology image sharing and personalized medicine

MyPHRMachines : personal health desktops in the cloud

Personal Health Records (PHRs) should remain the lifelong property of patients, who should be enabled to show them conveniently and securely to selected caregivers and institutions. Current solutions for PHRs focus on standard data exchange formats and transformations to move data across health information systems. In this paper we present MyPHRMachines, a PHR system taking a radically new architectural solution to health record interoperability. In MyPHRMachines, health-related data and the application software to view and/or analyze it are separately deployed in the PHR system. After uploading their medical data to MyPHRMachines, patients can access them again from remote virtual machines that contain the right software to visualize and analyze them without any conversion. Patients can share their remote virtual machine session with selected caregivers, who will need only aWeb browser to access the pre-loaded fragments of their lifelong PHR. We discuss a prototype of MyPHRMachines applied to two use cases, i.e. radiology image sharing and personalized medicine. The first use case demonstrates the ability of patients to build robust PHRs across the space and time dimensions, whereas the second use case demonstrates the ability of MyPHRMachines to preserve the privacy of PHR data deployed in the cloud

Post-depositional subsidence of the Avellino tephra marker bed in the Pontine plain (Lazio, Italy):Implications for Early Bronze Age palaeogeographical, water level and relative sea level reconstruction

Land subsidence has played and is still playing a significant role in coastal wetlands worldwide and in palaeogeographical reconstructions of such wetlands. The varying thickness of compaction-prone sediments over a stable subsurface is a key factor in determining its magnitude and in locating the most affected areas. In the coastal low-lying Agro Pontino (Lazio, Italy), subsidence of the past 90 years has been mapped using historical elevation data. Due to the fortunate preservation of distal Avellino tephra (AV-tephra, ca. 1900 cal. BCE) within its marshy strata, discovered a decade ago, detailed palaeogeographical reconstruction of the landscape in preparation for an assessment of its land use suitability in the Early Bronze Age (EBA) was possible. Current altitude variations of water-lain tephra in lake areas assumed to be connected necessitated a closer look at its original deposition altitude and the role of post-depositional subsidence. Recent subsidence patterns proved very useful for distinguishing stable from subsidence-prone areas. Two different EBA palaeo lake environments are distinguished: an inland and a near-coastal lake. The AV-tephra altitude variation within these lakes partly marks differential post-depositional subsidence within these lakes. Calculation of initial ripening of tephra-bearing lake deposits on top of shallowly buried Pleistocene ridges allowed for an estimation of original tephra deposition altitudes and associated lake levels. For the inland lake, a wide lake edge zone between 0.5 and 2 m above current sea level (m asl) was reconstructed, where EBA habitation or land use was possible. At the near-coastal lake, a water level of −1.5 to −1.3 m asl at the time of AV-tephra deposition was constrained. Because tephra deposition occurred here just after marine influence ceased, this altitude range is proposed to be a Relative Sea Level (RSL) index point at the time of AV-tephra deposition. The altitude range is in agreement with RSL models for tectonically stable areas in this region. The importance of subsidence in palaeogeographical, water level and RSL reconstructions in the region is stressed

MyPHRMachines: Lifelong Personal Health Records in the Cloud

Personal Health Records (PHRs) should remain the lifelong property of patients and should be showable conveniently and securely to selected caregivers. Regarding interoperability, current solutions for PHRs focus on standard data exchange formats and transformations to move data across health information systems. In this paper we propose MyPHRMachines, a patient-centric system that takes a radically new architectural solution to health record interoperability. We propose to deploy besides the medical data also the related software to the PHR system. After uploading their medical data to MyPHRMachines, patients can access them again from remote virtual machines that contain the right software to visualize and analyze them without any conversion. Patients can share their remote virtual machine session with a selected health provider, who will need only a Web browser to access the pre-loaded fragments of the lifelong PHR. We illustrate how our prototype already supports the use case of a real-world patient and discuss the research agenda required to translate this prototype into a viable solution for the international healthcare industry

Willingness to work for multinational enterprises from emerging countries:The case of Chinese multinational enterprises in the Netherlands

How do perceptions of country-of-origin image (COI) relate to willingness of Western people to work for subsidiaries in advanced countries of multinational enterprises from emerging countries (EMNEs)? We seek to shed light on this question by exploring six hypotheses based on environment-processing metatheory. Applying a PLS-SEM analysis of online survey data from the Netherlands, we find that the COI and familiarity with the EMNE's home country are positively associated with willingness to work. Additionally, we reveal a few mediating effects indicating that familiarity and individual difference are indirectly related to willingness to work. This study contributes to our understanding of the inability of EMNEs to attract talent in the Western world by adding a macro perspective to the human resource management literature. Furthermore, we extend environment-processing metatheory by expanding the focus from the perceived internal context (corporate information) to the perceived external environment (country of origin), as well as to the antecedents (familiarity and individual differences) of the perceived environment

Toward a model for digital tool criticism: Reflection as integrative practice

In the past decade, an increasing set of digital tools has been developed with which digital sources can be selected, analyzed, and presented. Many tools go beyond key word search and perform different types of analysis, aggregation, mapping, and linking of data selections, which transforms materials and creates new perspectives, thereby changing the way scholars interact with and perceive their materials. These tools, together with the massive amount of digital and digitized data available for humanities research, put a strain on traditional humanities research methods. Currently, there is no established method of assessing the role of digital tools in the research trajectory of humanities scholars. There is no consensus on what questions researchers should ask themselves to evaluate digital sources beyond those of traditional analogue source criticism. This article aims to contribute to a better understanding of digital tools and the discussion of how to evaluate and incorporate them in research, based on findings from a digital tool criticism workshop held at the 2017 Digital Humanities Benelux conference. The overall goal of this article is to provide insight in the actual use and practice of digital tool criticism, offer a ready-made format for a workshop on digital tool criticism, give insight in aspects that play a role in digital tool criticism, propose an elaborate model for digital tool criticism that can be used as common ground for further conversations in the field, and finally, provide recommendations for future workshops, researchers, data custodians, and tool builders

Beta asymmetry parameter in the decay of 114In

The beta asymmetry parameter A for the pure Gamow-Teller decay of 114In is reported. The low temperature nuclear orientation method was combined with a GEANT4 based simulation code allowing for the first time to address in detail the effects of scattering and of the magnetic field. The result, A = -0.994 +/- 0.010stat +/- 0.010syst, constitutes the most accurate value for the asymmetry parameter of a nuclear beta transition to date. The value is in agreement with the Standard Model prediction of A = -1 and provides new limits on tensor type charged weak currents.Comment: 11 pages, 2 figures; additional information was added on systematic effects, the magnetic field map and the calculation of the Qcos(theta) value