1,799 research outputs found
Modelling survival and connectivity of Mnemiopsis leidyi in the south-western North Sea and Scheldt estuaries
Three different models were applied to study the reproduction, survival and dispersal of Mnemiopsis leidyi in the Scheldt estuaries and the southern North Sea: a high-resolution particle tracking model with passive particles, a low-resolution particle tracking model with a reproduction model coupled to a biogeochemical model, and a dynamic energy budget (DEB) model. The results of the models, each with its strengths and weaknesses, suggest the following conceptual situation: (i) the estuaries possess enough retention capability to keep an overwintering population, and enough exchange with coastal waters of the North Sea to seed offshore populations; (ii) M. leidyi can survive in the North Sea, and be transported over considerable distances, thus facilitating connectivity between coastal embayments; (iii) under current climatic conditions, M. leidyi may not be able to reproduce in large numbers in coastal and offshore waters of the North Sea, but this may change with global warming; however, this result is subject to substantial uncertainty. Further quantitative observational work is needed on the effects of temperature, salinity and food availability on reproduction and on mortality at different life stages to improve models such as used here
Coordinated behavior of mitochondria in both space and time: a reactive species-activated wave of mitochondrial depolarization.
Reactive oxygen species (ROS) can trigger a transient burst of mitochondrial ROS production via ROS activation of the mitochondrial permeability transition pore (MPTP), a phenomenon termed ROS-induced ROS release (RIRR). The goal of this study was to investigate if the generation of ROS in a discrete region of a cardiomyocyte could serve to propagate RIRR-mediated mitochondrial depolarizations throughout a cell. Our experiments revealed that localized RIRR activated either RIRR-mediated fluctuations in mitochondrial membrane potential (time period: 3–10 min) or a traveling wave of depolarization of the cell's mitochondria (velocity: ∼5 μm/min). Both phenomena appeared to be mediated by the mitochondrial permeability transition pore and eventually encompassed the majority of the mitochondrial population of both isolated rat and rabbit cardiomyocytes. Furthermore, depolarization was often reversible; the waves of depolarization were then followed by a rapid (∼40 μm/min) repolarization wave of the mitochondria. We show that the RIRR can function to communicate the mitochondrial permeability transition from one mitochondrion to another in the isolated adult cardiomyocyte
Pelvic Rotation and Tilt Can Cause Misinterpretation of the Acetabular Index Measured on Radiographs
Bloch oscillations with a metastable helium Bose-Einstein condensate
We have observed Bloch oscillations of a 4He∗ Bose-Einstein condensate in an optical lattice at 1557.3 nm. Due to its low mass, metastable helium was efficiently accelerated orders of magnitude faster than demonstrated with other atoms. In a horizontal lattice, we could transfer a total of 800ℏk of momentum by shuttling the atomic cloud back and forth 50 times between the 4 k and -4 k momentum states with an efficiency of over 99% per Bloch cycle. In a vertical lattice, gravity-induced Bloch oscillations were demonstrated, from which the local gravitational acceleration was derived with a statistical uncertainty of 4×10-5. A clear advantage of He∗ over other atoms is that it can be detected with a microchannel plate detector with near unity efficiency, and this enabled observation of Bloch oscillations up to 12 s even though the number of atoms decreased by three orders of magnitude. These results establish He∗ as a promising candidate for future precision measurements with atom interferometry
New High Field State of Flux Line Lattice in Unconventional Superconductor CeCoIn_5
Ultrasound velocity measurements of the unconventional superconductor
CeCoIn_5 with extremely large Pauli paramagnetic susceptibility reveal an
unusual structural transformation of the flux line lattice (FLL) in the
vicinity of the upper critical field. The transition field coincides with that
at which heat capacity measurements reveal a second order phase transition. The
lowering of the sound velocity at the transition is consistent with the
collapse of the FLL tilt modulus and a crossover to quasi two-dimensional FLL
pinning. These results provide a strong evidence that the high field state is
the Fulde-Ferrel-Larkin-Ovchinikov phase, in which the order parameter is
spatially modulated and has planar nodes aligned perpendicular to the vortices.Comment: 5 pages, 4 figure
Modelling mangrove propagule dispersal: sensitivity analysis and implications for shrimp farm rehabilitation
info:eu-repo/semantics/publishedHexennial International Conference ‘Meeting on Mangrove ecology, functioning and Management – MMM3’, 2-6 juillet, Galle, Sri Lank
SOT-MRAM 300mm integration for low power and ultrafast embedded memories
We demonstrate for the first time full-scale integration of top-pinned
perpendicular MTJ on 300 mm wafer using CMOS-compatible processes for
spin-orbit torque (SOT)-MRAM architectures. We show that 62 nm devices with a
W-based SOT underlayer have very large endurance (> 5x10^10), sub-ns switching
time of 210 ps, and operate with power as low as 300 pJ.Comment: presented at VLSI2018 session C8-
MetaboLab - advanced NMR data processing and analysis for metabolomics
Background\ud
Despite wide-spread use of Nuclear Magnetic Resonance (NMR) in metabolomics for the analysis of biological samples there is a lack of graphically driven, publicly available software to process large one and two-dimensional NMR data sets for statistical analysis.\ud
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Results\ud
Here we present MetaboLab, a MATLAB based software package that facilitates NMR data processing by providing automated algorithms for processing series of spectra in a reproducible fashion. A graphical user interface provides easy access to all steps of data processing via a script builder to generate MATLAB scripts, providing an option to alter code manually. The analysis of two-dimensional spectra (1H,13C-HSQC spectra) is facilitated by the use of a spectral library derived from publicly available databases which can be extended readily. The software allows to display specific metabolites in small regions of interest where signals can be picked. To facilitate the analysis of series of two-dimensional spectra, different spectra can be overlaid and assignments can be transferred between spectra. The software includes mechanisms to account for overlapping signals by highlighting neighboring and ambiguous assignments.\ud
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Conclusions\ud
The MetaboLab software is an integrated software package for NMR data processing and analysis, closely linked to the previously developed NMRLab software. It includes tools for batch processing and gives access to a wealth of algorithms available in the MATLAB framework. Algorithms within MetaboLab help to optimize the flow of metabolomics data preparation for statistical analysis. The combination of an intuitive graphical user interface along with advanced data processing algorithms facilitates the use of MetaboLab in a broader metabolomics context.\ud
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Nonlinear DC-response in Composites: a Percolative Study
The DC-response, namely the - and - charateristics, of a variety
of composite materials are in general found to be nonlinear. We attempt to
understand the generic nature of the response charactersistics and study the
peculiarities associated with them. Our approach is based on a simple and
minimal model bond percolative network. We do simulate the resistor network
with appropritate linear and nonlinear bonds and obtain macroscopic nonlinear
response characteristics. We discuss the associated physics. An effective
medium approximation (EMA) of the corresponding resistor network is also given.Comment: Text written in RevTEX, 15 pages (20 postscript figures included),
submitted to Phys. Rev. E. Some minor corrections made in the text, corrected
one reference, the format changed (from 32 pages preprint to 15 pages
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