Dire necessity or mere opportunity? Recurring commercialization of peat exploited from raised bog commons in the Low Countries

Traditional commons scholarship, and in particular common-pool resource (CPR) theory, argues that historical commons institutions were autonomous, little influenced by either markets or states, and that commercialisation and sustainable collective use of common-pool resources were incompatible. This paper examines to what extent this view holds true. It does so by analysing historical sources on two local cases of peat commercialisation from raised bog commons in the early modern Low Countries: the Bakelse gemeint in the Peel region, and the commune de Xhoffraix in the Hautes Fagnes. The significance of peat commercialisation from commons was notably in its permanence, recurrence, and/or regional outreach, rather than in its limited volume share in total peat exploitation. Dire financial need of communities with high debts and taxes can partly explain the motives for peat commercialisation. Viewed over the longer term mere opportunity to gain some money was a plausible additional motive. In addition, stately institutions could influentially interfere in commons management in times of (internal) conflict. Sources indicate a pragmatic attitude towards peat commercialisation by these institutions, possibly to foster social peace and local prosperity in times of resource contestation and economic hardship. This study adds a novel intermediate category of peat exploitation to the traditional binary subdivision in domestic peat extraction from commons versus large-scale commercial exploitation of privatised bogs. We demonstrate that long-term use of common-pool resources could go together with a moderate degree of commercialisation. Rather than being fully autonomous, commons institutions were - structurally or at times of internal conflict - clearly impacted by markets, notions of private property, and stately institutions

Using legacy data to reconstruct the past? Rescue, rigour and reuse in peatland geochronology

There is a growing interest in the rescue and reuse of data from past studies (so-called legacy data). Data loss is alarming, especially where natural archives are under threat, such as peat deposits. Here we develop a workflow for reuse of legacy radiocarbon dates in peatland studies, including a rigorous quality assessment that can be tailored to specific research questions and study regions. A penalty is assigned to each date based on criteria that consider taphonomic quality (i.e., sample provenance) and dating quality (i.e., sample material and method used). The weights of quality criteria may be adjusted based on the research focus, and resulting confidence levels may be used in further analyses to ensure robustness of conclusions. We apply the proposed approach to a case study of a (former) peat landscape in the Netherlands, aiming to reconstruct the timing of peat initiation spatially. Our search yielded 313 radiocarbon dates from the 1950s to 2019. Based on the quality assessment, the dates—of highly diverse quality—were assigned to four confidence levels. Results indicate that peat initiation for the study area first peaked in the Late Glacial (~14,000 cal years BP), dropped during the Boreal (~9,500 cal years BP) and showed a second peak in the Subboreal (~4,500 cal years BP). We tentatively conclude that the earliest peak was mostly driven by climate (Bølling–Allerød interstadial), whereas the second was probably the result of Holocene sea level rise and related groundwater level rise in combination with climatic conditions (hypsithermal). Our study highlights the potential of legacy data for palaeogeographic reconstructions, as it is cost-efficient and provides access to information no longer available in the field. However, data retrieval may be challenging, and reuse of data requires that basic information on location, elevation, stratigraphy, sample and laboratory analysis are documented irrespective of the original research aims

Functional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitis.

Pneumococcal meningitis is the most frequent and critical type of bacterial meningitis. Because cytokines play an important role in the pathogenesis of bacterial meningitis, we examined whether functional polymorphisms of the proinflammatory cytokine macrophage migration inhibitory factor (MIF) were associated with morbidity and mortality of pneumococcal meningitis. Two functional MIF promoter polymorphisms, a microsatellite (-794 CATT5-8; rs5844572) and a single-nucleotide polymorphism (-173 G/C; rs755622) were genotyped in a prospective, nationwide cohort of 405 patients with pneumococcal meningitis and in 329 controls matched for age, gender, and ethnicity. Carriages of the CATT7 and -173 C high-expression MIF alleles were associated with unfavorable outcome (P= 0.005 and 0.003) and death (P= 0.03 and 0.01). In a multivariate logistic regression model, shock [odds ratio (OR) 26.0, P= 0.02] and carriage of the CATT7 allele (OR 5.12,P= 0.04) were the main predictors of mortality. MIF levels in the cerebrospinal fluid were associated with systemic complications and death (P= 0.0002). Streptococcus pneumoniae strongly up-regulated MIF production in whole blood and transcription activity of high-expression MIF promoter Luciferase reporter constructs in THP-1 monocytes. Consistent with these findings, treatment with anti-MIF immunoglogulin G (IgG) antibodies reduced bacterial loads and improved survival in a mouse model of pneumococcal pneumonia and sepsis. The present study provides strong evidence that carriage of high-expression MIF alleles is a genetic marker of morbidity and mortality of pneumococcal meningitis and also suggests a potential role for MIF as a target of immune-modulating adjunctive therapy

Calculation of minor hysteresis loops under metastable to stable transformations in vortex matter

We present a model in which metastable supercooled phase and stable equilibrium phase of vortex matter coexist in different regions of a sample. Minor hysteresis loops are calculated with the simple assumption of the two phases of vortex matter having field-independent critical current densities. We use our earlier published ideas that the free energy barrier separating the metastable and stable phases reduces as the magnetic induction moves farther from the first order phase transition line, and that metastable to stable transformations occur in local regions of the sample when the local energy dissipation exceeds a critical value. Previously reported anomalous features in minor hysteresis loops are reproduced, and calculated field profiles are presented.Comment: 9pages, 7 figure

Anthropogenic drivers for exceptionally large meander formation during the Late Holocene

Large-amplitude meanders may form in low-energy rivers despite generally limited mobility in theses systems. Exceptionally large meanders which even extend beyond the valley sides have developed in the Overijsselse Vecht river (the Netherlands) between ca. 1400 CE (Common Era) and the early 1900s, when channelization occurred. Previous studies have attributed the enhanced lateral dynamics of this river to changes in river regime due to increased discharges, reflecting climate and/or land-use alterations in the catchment. This paper focuses on local aspects that may explain why exceptionally large meanders developed at specific sites. Through an integrated analysis based on archaeological, historical, and geomorphological data along with optically stimulated luminescence dating, we investigated the relative impact of three direct and indirect anthropogenic causes for the local morphological change and enhanced lateral migration rates: (1) lack of strategies to manage fluvial erosion; (2) a strong increase in the number of farmsteads and related intensified local land use from the High Middle Ages onwards; and (3) (human-induced) drift-sand activity directly adjacent to the river bends, causing a change in bank stability. Combined, these factors led locally to meander amplitudes well beyond the valley sides. Lessons learned at this site are relevant for management and restoration of meandering rivers in similar settings elsewhere, particularly in meeting the need to estimate spatial demands of (restored) low-energy fluvial systems and manage bank erosion.</p

Supercooling of the disordered vortex lattice in Bi_2Sr_2CaCu_2O_8+d

Time-resolved local induction measurements near to the vortex lattice order-disorder transition in optimally doped Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$_{8+\delta}$ single crystals shows that the high-field, disordered phase can be quenched to fields as low as half the transition field. Over an important range of fields, the electrodynamical behavior of the vortex system is governed by the co-existence of the two phases in the sample. We interpret the results in terms of supercooling of the high-field phase and the possible first order nature of the order-disorder transition at the ``second peak''.Comment: 4 pages, 3 figures. Submitted to Nature, July 10th, 1999; Rejected August 8th for lack of broad interest Submitted to Physical Review Letters September 10th, 199

Disorder and thermally driven vortex-lattice melting in La{2-x}Sr{x}CuO{4} crystals

Magnetization measurements in La{2-x}Sr{x}CuO{4} crystals indicate vortex order-disorder transition manifested by a sharp kink in the second magnetization peak. The transition field exhibits unique temperature dependence, namely a strong decrease with temperature in the entire measured range. This behavior rules out the conventional interpretation of a disorder-driven transition into an entangled vortex solid phase. It is shown that the transition in La{2-x}Sr{x}CuO{4} is driven by both thermally- and disorder-induced fluctuations, resulting in a pinned liquid state. We conclude that vortex solid-liquid, solid-solid and solid to pinned-liquid transitions are different manifestations of the same thermodynamic order-disorder transition, distinguished by the relative contributions of thermal and disorder-induced fluctuations.Comment: To be published in phys. Rev. B Rapid Com

Long-Term Safety of Growth Hormone in Adults With Growth Hormone Deficiency:Overview of 15 809 GH-Treated Patients

Context Data on long-term safety of growth hormone (GH) replacement in adults with GH deficiency (GHD) are needed. Objective We aimed to evaluate the safety of GH in the full KIMS (Pfizer International Metabolic Database) cohort. Methods The worldwide, observational KIMS study included adults and adolescents with confirmed GHD. Patients were treated with GH (Genotropin [somatropin]; Pfizer, NY) and followed through routine clinical practice. Adverse events (AEs) and clinical characteristics (eg, lipid profile, glucose) were collected. Results A cohort of 15 809 GH-treated patients were analyzed (mean follow-up of 5.3 years). AEs were reported in 51.2% of patients (treatment-related in 18.8%). Crude AE rate was higher in patients who were older, had GHD due to pituitary/hypothalamic tumors, or adult-onset GHD. AE rate analysis adjusted for age, gender, etiology, and follow-up time showed no correlation with GH dose. A total of 606 deaths (3.8%) were reported (146 by neoplasms, 71 by cardiac/vascular disorders, 48 by cerebrovascular disorders). Overall, de novo cancer incidence was comparable to that in the general population (standard incidence ratio 0.92; 95% CI, 0.83-1.01). De novo cancer risk was significantly lower in patients with idiopathic/congenital GHD (0.64; 0.43-0.91), but similar in those with pituitary/hypothalamic tumors or other etiologies versus the general population. Neither adult-onset nor childhood-onset GHD was associated with increased de novo cancer risks. Neutral effects were observed in lipids/fasting blood glucose levels. Conclusion These final KIMS cohort data support the safety of long-term GH replacement in adults with GHD as prescribed in routine clinical practice

Unified order-disorder vortex phase transition in high-Tc superconductors

The diversity of vortex melting and solid-solid transition lines measured in different high-T$_{c}$ superconductors is explained, postulating a unified order-disorder phase transition driven by both thermally- and disorder-induced fluctuations. The temperature dependence of the transition line and the nature of the disordered phase (solid, liquid, or pinned liquid) are determined by the relative contributions of these fluctuations and by the pinning mechanism. By varying the pinning mechanism and the pinning strength one obtains a spectrum of monotonic and non-monotonic transition lines similar to those measured in Bi$_{2}$Sr$_{2}$CaCu$_{2}$O$$, YBa$_{2}$Cu$_{3}$O$_{7-\delta}$, Nd$_{1.85}$Ce$_{0.15}$CuO$$, Bi$_{1.6}$Pb$_{0.4}$Sr$_{2}$CaCu$_{2}$O$_{8+\delta}$ and (La$_{0.937}$Sr$_{0.063}$)$_{2}$CuO$_{4}$Comment: To be published in Phys. Rev. B Rapid Com