EVALUATING THE NUTRITIVE PROPERTIES OF MIXED PLANT DERIVED PRODUCTS WITH AND WITHOUT SOYAMILK FOR PHARMACOLOGICAL USAGE

Objective: Normally this day's nutritive products are available, but most of them are synthetic made materials which have low quality ingredients and for storage purpose it is coated with phenolic compounds. It is not at all harmful, though it is not fully absorbed by our body receptors in intestine and way too costly the products are these days. To compensate this issue we have evaluated the nutritive properties of mixed plant derived products with and without soyamilk. Methods: Natural existing products like Moringa olifera leaves, spinach leaves, Colocasia fruit part were obtained from the concerned source and they were powdered and crude extract are used to mix along methanol extract. This extract is used for estimation of antioxidants, phenols, vitamins and carbohydrate. Later extract is dissolved in soyamilk, the studies of interaction and various biochemical methods are carried out. Results: These studies showed the presence of phenols were higher in the soya milk which makes it contiguous and stagnant. Conclusion: Comparison studies are made between soyamilk after mixing the extract in multiple standards.Keywords:Nutritive products, Soyamilk, Moringa Olifera, Carbohydrate

Sharing of Data Using Key Aggregation and Searchable Encryption

Sharing data with different users is an important functionality of the cloud. However, while enjoying the convenience provided by the cloud storage, user’s main concern is regarding the data leakage present in cloud. A promising approach to prevent this is encryption of data before uploading onto cloud. The desire to selectively and securely share documents with any group of users demands different documents to have different encryption keys. This necessitates the distribution of a large number of keys to users for both encryption and search, those users will have to securely store these keys, and submit an equally large number of keyword trapdoors to the cloud in order to perform search. In this paper, we resolve this problem by extending the concept of Key Aggregate Searchable Encryption (KASE) scheme which employs a single aggregate key and a single trapdoor. Here, the data owner only needs to distribute a single key to a user for sharing a large number of documents, and the user only needs to submit a single trapdoor to the cloud for querying the documents. Also, we provide a functionality of selection of keyword based on their rank by the Data owner in such a way that the selected keywords describe the file. Thus, this scheme makes the management of the keys efficient and also makes the sharing of documents over the cloud more secure

RNAI MEDIATED GENE SILENCING OF EIF3A: A POSSIBLE SOLUTION TO CONTROL BREAST CANCER

Objective: The eukaryotic translational initiation factor 3A (eIF3A) is reported to be over expressed in most breast cancer cells. In the present study, our aim is to suppress the over expression of eIF3A in human breast cancer MCF-7 cell line using gene silencing technique (RNA interference (RNAi)).Methods: The artificial microRNA (amiRNA) targeting eIF3A gene was constructed by incorporating short interference RNA (siRNA) sequences against eIF3A gene into endogenous microRNA30 (miR-30) and cloned into pcDNA3.1 vector. The amiRNA containing plasmid was then transfected into MCF-7 cell line and the expression of eIF3A was examined by RT-PCR. The cytotoxicity of plasmid with amiRNA targeting eIF3A on MCF–7 cells was evaluated by MTT assay.Results: The amiRNA construct significantly inhibited eIF3A gene expression and reduce the cell viability of MCF-7 cell line.Conclusion: The usage of modified endogenous amiRNA in vector based expression system with significant gene silencing efficiency suggests that RNAi based gene silencing method can be considered as one of the effective means to control cancer.Â

Biodiesel and green diesel generation: An overview

First, second, third, and fourth-generation biofuels are continuously evolving as a promising substitute to petrodiesel catalyzed by energy depletion, economic and environmental considerations. Bio-diesel can be synthesized from various biomass sources, which are commonly divided into FAME and renewable biodiesel. FAME biodiesel is generally produced by the transesterification of vegetable oils and fats while renewable diesel is produced by hydro-deoxygenation of vegetable and waste oils and fats. The different generation, processing technologies and standards for FAME and renewable biodiesel are reviewed. Finally, the life cycle analysis and production cost of conventional and renewable biodiesel are described

Advancements in Compiler Design and Optimization Techniques

The modern period has seen advancements in compiler design, optimization technique, and software system efficiency. The influence of the most recent developments in compiler design and optimization techniques on program execution speed, memory utilization, and overall software quality is highlighted in this study. The design of the compiler is advanced by the efficient code that is now structured in research with high-speed performance without manual intervention. The influence of the most recent developments in compiler design and optimization techniques on program execution speed, memory utilization, and overall software quality is highlighted in this paper's thorough analysis

System for Water Quality Monitoring and Distribution

Water plays a vital role in the creation of human being and other natural phenomena. More than 80% of the resources is surrounded by water but in that only 20% is good for consumption others are fully polluted and contaminated. Now a days water is more polluted, and even supplied in a very lesser level so to check and monitor the quality of the water we mainly using a number of sensors are used to monitor the water’s quality and distribute it to the less fortunate. The quality of the water is affected by several parameters. Water is provided from difference resources like lake, pond, well, ground water, oceans etc.so these waters are not good for consumption Therefore, our goal is to assess the water’s quality while keeping an eye on the flow and level of the water. It is intended to use a variety of cutting-edge devices to check various water quality system parameters

Improved control strategy of DFIG-based wind turbines using direct torque and direct power control techniques

This paper presents different control strategies for a variable-speed wind energy conversion system (WECS), based on a doubly fed induction generator. Direct Torque Control (DTC) with Space-Vector Modulation is used on the rotor side converter. This control method is known to reduce the fluctuations of the torque and flux at low speeds in contrast to the classical DTC, where the frequency of switching is uncontrollable. The reference for torque is obtained from the maximum power point tracking technique of the wind turbine. For the grid-side converter, a fuzzy direct power control is proposed for the control of the instantaneous active and reactive power. Simulation results of the WECS are presented to compare the performance of the proposed and classical control approaches.Peer reviewedFinal Accepted Versio

Prevalence of intestinal parasitic infections among HIV patients in Benin City, Nigeria

This study was carried out to determine the presence of intestinal parasites and their correlation with CD4+ T-cell counts and demographics among human immunodeficiency virus (HIV)-positive patients in Benin City, Nigeria. Stool specimens from 2,000 HIV-positive patients and 500 controls (HIV-negative individuals) were examined for ova, cysts, or parasites, using standard procedures. In addition, patient's blood samples were analyzed for CD4 counts by flow cytometry. An overall prevalence rate of 15.3% was observed among HIV-positive patients while 6.2% was noted among non-HIV subjects. HIV status was a significant (P<0.0001) risk factor for acquiring intestinal parasitic infections. Male gender, CD4 count <200cell/µl, and diarrhea were significantly associated with an increased prevalence of intestinal parasitic infections among HIV-positive patients. The level of education, occupation, and source of water among HIV patients significantly (P<0.0001) affected the prevalence of intestinal parasitic infections. Ascaris lumbricoides was the most predominant parasite in both HIV-positive patients and controls. A CD4 count <200 cells/µl was significantly associated with only Isospora belli and Cryptosporidium infections. The presence of pathogenic intestinal parasites such as A. lumbricoides, hookworm, Giardia intestinalis, Entamoeba histolytica, Trichuris trichiura, and Taenia species among HIV-infected persons should not be neglected. Cryptosporidium species and I. belli were the opportunistic parasites observed in this study. Routine screening for intestinal parasites in HIV-positive patients is advocated

Researching COVID to Enhance Recovery (RECOVER) Adult Study Protocol: Rationale, Objectives, and Design

IMPORTANCE: SARS-CoV-2 infection can result in ongoing, relapsing, or new symptoms or other health effects after the acute phase of infection; termed post-acute sequelae of SARS-CoV-2 infection (PASC), or long COVID. The characteristics, prevalence, trajectory and mechanisms of PASC are ill-defined. The objectives of the Researching COVID to Enhance Recovery (RECOVER) Multi-site Observational Study of PASC in Adults (RECOVER-Adult) are to: (1) characterize PASC prevalence; (2) characterize the symptoms, organ dysfunction, natural history, and distinct phenotypes of PASC; (3) identify demographic, social and clinical risk factors for PASC onset and recovery; and (4) define the biological mechanisms underlying PASC pathogenesis. METHODS: RECOVER-Adult is a combined prospective/retrospective cohort currently planned to enroll 14,880 adults aged ≥18 years. Eligible participants either must meet WHO criteria for suspected, probable, or confirmed infection; or must have evidence of no prior infection. Recruitment occurs at 86 sites in 33 U.S. states, Washington, DC and Puerto Rico, via facility- and community-based outreach. Participants complete quarterly questionnaires about symptoms, social determinants, vaccination status, and interim SARS-CoV-2 infections. In addition, participants contribute biospecimens and undergo physical and laboratory examinations at approximately 0, 90 and 180 days from infection or negative test date, and yearly thereafter. Some participants undergo additional testing based on specific criteria or random sampling. Patient representatives provide input on all study processes. The primary study outcome is onset of PASC, measured by signs and symptoms. A paradigm for identifying PASC cases will be defined and updated using supervised and unsupervised learning approaches with cross-validation. Logistic regression and proportional hazards regression will be conducted to investigate associations between risk factors, onset, and resolution of PASC symptoms. DISCUSSION: RECOVER-Adult is the first national, prospective, longitudinal cohort of PASC among US adults. Results of this study are intended to inform public health, spur clinical trials, and expand treatment options

Track A Basic Science

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/138319/1/jia218438.pd