Report of Virtual Conference. BASICS Phase I - Achievements and Learnings Meeting. May 18-19, 2020

The Building an Economically Sustainable Integrated Cassava Seed System in Nigeria (BASICS) project began in 2016 and formally ends on 30 June 2020. The project has made progress in demonstrating that commercially viable production and sale of breeder, foundation and certified seed is possible. Furthermore, the project has established a strong basis for building a sustainable seed system by developing building blocks across the seed value chain. This meeting had the following objectives: 1. To identify the achievements and lessons learned in each of the project components; 2. To identify the shortcomings in each component (what would I do differently, knowing what I know now?), remaining challenges and ideas to overcome them; 3. To assess and discuss the challenges and progress made in integrating the components into an integrated seed system and identify ways integration can be improved; 4. To assess and discuss the commercial sustainability of the seed system and identify options to promote its sustainability and further scaling; and 5. To make plans for the publication of the findings and lessons learned during BASICS-

Multiple extensions of a finite Euler's pentagonal number theorem and the Lucas formulas

Motivated by the resemblance of a multivariate series identity and a finite analogue of Euler's pentagonal number theorem, we study multiple extensions of the latter formula. In a different direction we derive a common extension of this multivariate series identity and two formulas of Lucas. Finally we give a combinatorial proof of Lucas' formulas.Comment: 11 pages, to appear in Discrete Mathematics. See also http://math.univ-lyon1.fr/~gu

Rasch analysis of the Patient Rated Elbow Evaluation questionnaire

© 2015 Vincent et al. Background: The Patient Rated Elbow Evaluation (PREE) was developed as an elbow joint specific measure of pain and disability and validated with classical psychometric methods. More recently, Rasch analysis has contributed new methods for analyzing the clinical measurement properties of self-report outcome measures. The objective of the study was to determine aspects of validity of the PREE using the Rasch model to assess the overall fit of the PREE data, the response scaling, individual item fit, differential item functioning (DIF), local dependency, unidimensionality and person separation index (PSI). Methods: A convenience sample of 236 patients (Age range 21-79 years; M: F- 97:139) with elbow disorders were recruited from the Roth|McFarlane Hand and Upper Limb Centre, London, Ontario, Canada. The baseline scores of the PREE were used. Rasch analysis was conducted using RUMM 2030 software on the 3 sub scales of the PREE separately. Results: The 3 sub scales showed misfit initially with disordered thresholds on17 out of 20 items), uniform DIF was observed for two items ( Carrying a 10lbs object from specific activities subscale for age group; and household work from the usual activities subscale for gender); multidimensionality and local dependency. The Pain subscale satisfied Rasch expectations when item 2 Pain - At rest was split for age group, while the usual activities subscale readily stood up to Rasch requirements when the item 2 household work was split for gender. The specific activities subscale demonstrated fit to the Rasch model when sub test analysis accounted for local dependency. All three subscales of the PREE were well targeted and had high reliability (PSI \u3e0.80). Conclusion: The three subscales of the PREE appear to be robust when tested against the Rasch model when subject to a few alterations. The value of changing the 0-10 format is questionable given its widespread use; further Rasch-based analysis of whether these findings are stable in other samples is warranted

An In Vitro Study of the Role of Implant Positioning on Ulnohumeral Articular Contact in Distal Humeral Hemiarthroplasty

© 2017 American Society for Surgery of the Hand Purpose To investigate the effect of implant positioning on ulnohumeral contact using patient-specific distal humeral (DH) implants. Methods Seven reverse-engineered DH implants were manufactured based on computed tomography scans of their osseous geometry. Native ulnae were paired with corresponding native humeri and custom DH implants in a loading apparatus. The ulna was set at 90° of flexion and the humeral component (either native bone or reverse-engineered implant) was positioned from 5° varus to 5° valgus in 2.5° increments under a 100-N compressive load. Contact with the ulna was measured with both the native distal humerus and the reverse-engineered DH implant at all varus-valgus (VV) angles, using a joint casting method. Contact patches were digitized and analyzed in 4 ulnar quadrants. Output variables were contact area and contact pattern. Results Mean contact area of the native articulation was significantly greater than with the distal humeral hemiarthroplasty (DHH) implants across all VV positions. Within the native condition, contact area did not significantly change owing to VV angulation. Within the DHH condition, contact area also did not significantly change owing to VV angulation. Conversely, in the DHH condition, contact pattern did significantly change. Medial ulnar contact pattern was significantly affected by VV angulation. Lateral ulnar contact was variably affected, but generally decreased as well. Conclusions Ulnar contact patterns were changed as a result of VV implant positioning using reverse-engineered DH implants, most notably on the medial aspect of the joint. Implant positioning plays a crucial role in producing contact patterns more like those observed in the native joint. Clinical relevance Recent clinical evidence reports nonsymmetrical ulnar wear after DHH. This work suggests that implant positioning is likely a contributing factor and that more exact implant positioning may lead to better clinical outcomes

The Effect of Radial Head Hemiarthroplasty Stem Fit on Radiocapitellar Contact Mechanics: Is Loose Fit better than Rigidly Fixed?

Background/Methods: Radial head hemiarthroplasty is commonly employed to manage comminuted displaced fractures. With regards to implant fixation, current designs vary with some prostheses aiming to achieve a tight \u27fixed\u27 fit, and others utilizing a smooth stem with an over reamed \u27loose\u27 fit. The purpose of the present study was to evaluate the effect of radial head hemiarthroplasty stem fit on radiocapitellar contact using a finite element model which simulated both fixed (size-for-size) and loose (1, 2 & 3mm over reamed) stem fits. Hypothesis: It was hypothesized that a loose stem fit would improve radiocapitellar contact mechanics, with increased contact area and decreased contact stress, by allowing the implant to find its \u27optimal\u27 position with respect to the capitellum. Results/Discussion: This data suggests that the loose smooth stem radial head implant may be functioning like a bipolar implant in optimizing radiocapitellar contact. The \u27loose\u27 over reamed stem provided optimal contact mechanics of the metallic axisymmetric radial head implant compared to the \u27fixed\u27 stem. The 1mm over reamed stem reduced maximum contact stress without affecting contact area. Over reaming of 2mm provided the greatest decrease in maximum contact stress, albeit with a significant reduction in contact area. Over reaming of 3mm produced a larger amount of stress concentrations on the capitellum suggesting there may be a limit to how loose a smooth stem implant should be implanted

Services within a busy period of an M/M/1 queue and Dyck paths

We analyze the service times of customers in a stable M/M/1 queue in equilibrium depending on their position in a busy period. We give the law of the service of a customer at the beginning, at the end, or in the middle of the busy period. It enables as a by-product to prove that the process of instants of beginning of services is not Poisson. We then proceed to a more precise analysis. We consider a family of polynomial generating series associated with Dyck paths of length 2n and we show that they provide the correlation function of the successive services in a busy period with (n+1) customers

Case studies of Roots, Tubers and Bananas seed systems.

The seed systems of RTB (root, tuber, and banana) crops are unique because they are propagated from vegetative parts of the plant, not from true seed. RTB seed is thus bulkier, more perishable, and more subject to the attacks of pests and diseases than is true seed. Because of this, there is often a gap between potential and real crop yields, which seed interventions seek to narrow. Seed systems are formal or informal networks of people and organizations that produce, plant, and distribute seed. Informal systems may deliver low quality seed, but not always. This book describes 13 RTB seed system interventions, using a framework based on the concepts of seed availability, access, and quality. The 13 case studies included (1) a potato-growers’ association in Ecuador, (2) a hydroponic seed potato in Peru, (3) a yam seed technology in Nigeria, (4) a banana and plantain project in Ghana, (5) a sweetpotato seed project in Tanzania and (6) one in Rwanda, (7) a seed potato system in Kenya, (8) cassava in Nicaragua, (9) seed potato in Malawi, (10) disease-resistant cassava varieties in seven African countries, (11) a tissue culture banana project, (12) an emergency plantain and banana project in East Africa, and (13) a large cassava seed project in six African countries

Evaluation of a computational model to predict elbow range of motion

© 2014 The Author(s). Computer models capable of predicting elbow flexion and extension range of motion (ROM) limits would be useful for assisting surgeons in improving the outcomes of surgical treatment of patients with elbow contractures. A simple and robust computer-based model was developed that predicts elbow joint ROM using bone geometries calculated from computed tomography image data. The model assumes a hinge-like flexion-extension axis, and that elbow passive ROM limits can be based on terminal bony impingement. The model was validated against experimental results with a cadaveric specimen, and was able to predict the flexion and extension limits of the intact joint to 0° and 3°, respectively. The model was also able to predict the flexion and extension limits to 1° and 2°, respectively, when simulated osteophytes were inserted into the joint. Future studies based on this approach will be used for the prediction of elbow flexion-extension ROM in patients with primary osteoarthritis to help identify motion-limiting hypertrophic osteophytes, and will eventually permit real-time computer-assisted navigated excisions

The effect of implant linking and ligament integrity on humeral loading of a convertible total elbow arthroplasty

© 2017 The British Elbow & Shoulder Society. Background: Both unlinked and linked total elbow arthroplasty (TEA) implants have been employed with no consensus as to the optimal design. The present study aimed to evaluate the effect of collateral ligament integrity and implant linkage on wear-inducing loads in a convertible TEA. Methods: Eight fresh frozen upper extremities were tested in an elbow motion simulator. A convertible TEA with an instrumented humeral stem was inserted using computer navigation. Elbow kinematics and humeral loading were recorded with the TEA both linked and unlinked. The collateral ligaments were then sectioned and testing was repeated. Results: In the dependent position, there was no effect of implant linkage or ligament sectioning on humeral loading. Humeral loading was significantly greater following sectioning of the collateral ligaments but not after linking the TEA with the arm in the valgus position. Humeral loading was significantly greater after linking the TEA but not after sectioning of the collateral ligaments and with the arm in the varus position. Conclusions: Collateral ligament integrity reduces wear-inducing loads for both an unlinked and linked TEA. Linkage of a convertible TEA increases humeral loading, which may have detrimental effects on implant longevity

Planning an integrated agriculture and health program and designing its evaluation: Experience from Western Kenya.

AbstractMulti-sectoral programs that involve stakeholders in agriculture, nutrition and health care are essential for responding to nutrition problems such as vitamin A deficiency among pregnant and lactating women and their infants in many poor areas of lower income countries. Yet planning such multi-sectoral programs and designing appropriate evaluations, to respond to different disciplinary cultures of evidence, remain a challenge. We describe the context, program development process, and evaluation design of the Mama SASHA project (Sweetpotato Action for Security and Health in Africa) which promoted production and consumption of a bio-fortified, orange-fleshed sweetpotato (OFSP). In planning the program we drew upon information from needs assessments, stakeholder consultations, and a first round of the implementation evaluation of a pilot project. The multi-disciplinary team worked with partner organizations to develop a program theory of change and an impact pathway which identified aspects of the program that would be monitored and established evaluation methods. Responding to the growing demand for greater rigour in impact evaluations, we carried out quasi-experimental allocation by health facility catchment area, repeat village surveys for assessment of change in intervention and control areas, and longitudinal tracking of individual mother-child pairs. Mid-course corrections in program implementation were informed by program monitoring, regular feedback from implementers and partners’ meetings. To assess economic efficiency and provide evidence for scaling we collected data on resources used and project expenses. Managing the multi-sectoral program and the mixed methods evaluation involved bargaining and trade-offs that were deemed essential to respond to the array of stakeholders, program funders and disciplines involved