The s-process nucleosynthesis : Impact of the uncertainties in the nuclear physics determined by monte carlo variations

We investigated the impact of uncertainties in neutron-capture and weak reactions (on heavy elements) on the s-process nucleosynthesis in low-mass stars and massive stars using a Monte-Carlo based approach. We performed extensive nuclear reaction network calculations that include newly evaluated temperature-dependent upper and lower limits for the individual reaction rates. We found β-decay rate uncertainties affect only a few nuclei near s-process branchings, whereas most of the uncertainty in the final abundances is caused by uncertainties in the neutron capture rates. We suggest a list of uncertain rates as candidates for improved measurement by future experiments.Peer reviewe

The s-Process Nucleosynthesis in Low Mass Stars : Impact of the Uncertainties in the Nuclear Physics Determined by Monte Carlo Variations

© Springer Nature Switzerland AG 2019We investigated the impact of uncertainties in neutron-capture and weak reactions (on heavy elements) on the s-process nucleosynthesis in low-mass stars using a Monte-Carlo based approach. We performed extensive nuclear reaction network calculations that include newly evaluated temperature-dependent upper and lower limits for the individual reaction rates. Our sophisticated approach is able to evaluate the reactions that impact more significantly the final abundances. We found that -decay rate uncertainties affect typically nuclides near s-process branchings, whereas most of the uncertainty in the final abundances is caused by uncertainties in neutron capture rates, either directly producing or destroying the nuclide of interest. Combined total nuclear uncertainties due to reactions on heavy elements are approximately 50%

Sex ratio evolution in a variable environment

We develop a natural selection model for sex ratio control in a spatially variable environment. Predictions of sex ratio alteration as a function of environmental change are tested in laboratory experiments with two parasitic wasps. Field data from a variety of other organisms also support the model. Finally, we discuss possibilities and difficulties for testing this type of evolutionary model

Antidiabetic Properties of Naringenin: A Citrus Fruit Polyphenol

Type 2 diabetes mellitus (T2DM) is a metabolic disease characterized by insulin resistance and hyperglycemia and is associated with personal health and global economic burdens. Current strategies/approaches of insulin resistance and T2DM prevention and treatment are lacking in efficacy resulting in the need for new preventative and targeted therapies. In recent years, epidemiological studies have suggested that diets rich in vegetables and fruits are associated with health benefits including protection against insulin resistance and T2DM. Naringenin, a citrus flavanone, has been reported to have antioxidant, anti-inflammatory, hepatoprotective, nephroprotective, immunomodulatory and antidiabetic properties. The current review summarizes the existing in vitro and in vivo animal studies examining the anti-diabetic effects of naringeninBrock University Library Open Access Publishing Fun

Impacts of nuclear-physics uncertainty in stellar temperatures on the s-process nucleosynthesis

N. Nishimura, G. Cescutti, R. Hirschi, T. Rauscher, J. Den Hartogh, and A. St J. Murphy, 'Impacts of nuclear-physics uncertainty in stellar temperatures on the s-process nucleosynthesis', in Proceedings of the 14th International Symposium on Nuclei in the Cosmos (NIC2016). Niigata, Japan. June 19-24, 2016. ISBN: 978-4-89027-118-4. DOI: http://dx.doi.org/10.7566/JPSCP.14.020903 © 2017 The Physical Society of Japan.We evaluated the uncertainty relevant to s-process nucleosynthesis using a Monte-Carlo centred approach. We are based on a realistic and general prescription of temperature dependent uncertainty for the reactions. We considered massive stars for the weak s-process and AGB stars for the main s-process. We found that the adopted uncertainty for (n,$\gamma$) rates, tens of per cent on average, affect the production of s-process nuclei along the $\beta$-stability line, while for $\beta$-decay, for which contributions from excited states enhances the uncertainty, has the strongest impact on branching points

In the best interests of the deceased: A possible justification for organ removal without consent?

Opt-out systems of postmortem organ procurement are often supposed to be justifiable by presumed consent, but this justification turns out to depend on a mistaken mental state conception of consent. A promising alternative justification appeals to the analogical situation that occurs when an emergency decision has to be made about medical treatment for a patient who is unable to give or withhold his consent. In such cases, the decision should be made in the best interests of the patient. The analogous suggestion to be considered, then, is, if the potential donor has not registered either his willingness or his refusal to donate, the probabilities that he would or would not have preferred the removal of his organs need to be weighed. And in some actual cases the probability of the first alternative may be greater. This article considers whether the analogy to which this argument appeals is cogent, and concludes that there are important differences between the emergency and the organ removal cases, both as regards the nature of the interests involved and the nature of the right not to be treated without one’s consent. Rather, if opt-out systems are to be justified, the needs of patients with organ failure and/or the possibility of tacit consent should be considered

Role of the Myokine Irisin on Bone Homeostasis: Review of the Current Evidence

Bone is a highly dynamic tissue that is constantly adapting to micro-changes to facilitate movement. When the balance between bone building and resorption shifts more towards bone resorption, the result is reduced bone density and mineralization, as seen in osteoporosis or osteopenia. Current treatment strategies aimed to improve bone homeostasis and turnover are lacking in efficacy, resulting in the search for new preventative and nutraceutical treatment options. The myokine irisin, since its discovery in 2012, has been shown to play an important role in many tissues including muscle, adipose, and bone. Evidence indicate that irisin is associated with increased bone formation and decreased bone resorption, leading to reduced risk of osteoporosis in post-menopausal women. In addition, low serum irisin levels have been found in individuals with osteoporosis and osteopenia. Irisin targets key signaling proteins, promoting osteoblastogenesis and reducing osteoclastogenesis. The present review summarizes the existing evidence regarding the effects of irisin on bone homeostasis.Brock Library Open Access Publishing Fun

Anticancer Properties of Carnosol: A Summary of In Vitro and In Vivo Evidence

Cancer is characterized by unrestricted cell proliferation, inhibition of apoptosis, enhanced invasion and migration, and deregulation of signalling cascades. These properties lead to uncontrolled growth, enhanced survival, and the formation of tumours. Carnosol, a naturally occurring phyto-polyphenol (diterpene) found in rosemary, has been studied for its extensive antioxidant, anti-inflammatory, and anticancer effects. In cancer cells, carnosol has been demonstrated to inhibit cell proliferation and survival, reduce migration and invasion, and significantly enhance apoptosis. These anticancer effects of carnosol are mediated by the inhibition of several signalling molecules including extracellular signal-regulated kinase (ERK), p38, c-Jun N-terminal kinase (JNK), Akt, mechanistic target of rapamycin (mTOR) and cyclooxygenase-2 (COX-2). Additionally, carnosol prevents the nuclear translocation of nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) and promotes apoptosis, as indicated by increased levels of cleaved caspase-3, -8, -9, increased levels of the pro-apoptotic marker Bcl-2-associated X (BAX), and reduced levels of the anti-apoptotic marker B-cell lymphoma 2 (Bcl-2). The current review summarizes the existing in vitro and in vivo evidence examining the anticancer effects of carnosol across various tissues

The s process in rotating low-mass AGB stars: Nucleosynthesis calculations in models matching asteroseismic constraints

Aims. We investigate the s-process during the AGB phase of stellar models whose cores are enforced to rotate at rates consistent with asteroseismology observations of their progenitors and successors. Methods. We calculated new 2 M⊙ , Z  =  0.01 models, rotating at 0, 125, and 250 km s-1 at the start of main sequence. An artificial, additional viscosity was added to enhance the transport of angular momentum in order to reduce the core rotation rates to be in agreement with asteroseismology observations. We compared rotation rates of our models with observed rotation rates during the MS up to the end of core He burning, and the white dwarf phase. Results. We present nucleosynthesis calculations for these rotating AGB models that were enforced to match the asteroseismic constraints on rotation rates of MS, RGB, He-burning, and WD stars. In particular, we calculated one model that matches the upper limit of observed rotation rates of core He-burning stars and we also included a model that rotates one order of magnitude faster than the upper limit of the observations. The s-process production in both of these models is comparable to that of non-rotating models. Conclusions. Slowing down the core rotation rate in stars to match the above mentioned asteroseismic constraints reduces the rotationally induced mixing processes to the point that they have no effect on the s-process nucleosynthesis. This result is independent of the initial rotation rate of the stellar evolution model. However, there are uncertainties remaining in the treatment of rotation in stellar evolution, which need to be reduced in order to confirm our conclusions, including the physical nature of our approach to reduce the core rotation rates of our models, and magnetic processes