Etiology and susceptbility to antimicrobials of urinary tract infections in patients of Rehabilitation Unit of a regional hospital

Objetivos: Conocer los resultados del estudio microbiológico de las muestras de orina de pacientes de la Unidad de Rehabilitación de un hospital regional, incluyendo los datos locales de sensibilidad antibiótica. Material y métodos: Se analizó la base de datos del Laboratorio de Microbiología del Hospital Universitario Virgen de las Nieves con los estudios microbiológicos de las muestras de orinas realizados durante el año 2012. Se investigó la etiología y la sensibilidad a los antibióticos de los uropatógenos más frecuentes presentes en 143 muestras de orina obtenidas mediante sondaje o cateterismo. Los resultados del estudio de 9066 muestras de orina de micción media de sujetos estudiados en Atención Primaria fueron utilizados como grupo control. Resultados: El 50% de los pacientes neurológicos presentaron urocultivos positivos, frente al 23% de los controles. E. coli fue el microorganismo más frecuentemente aislado en el grupo de enfermos neurológicos, al igual que en los controles. En el estudio de resistencias E. coli presentó altas tasas de resistencia a ampicilina, cotrimoxazol, ciprofloxacino y amoxicilina con ácido clavulánico. Conclusiones: E. coli es el microorganismo más frecuentemente aislado en los dos grupos de pacientes estudiados. Las resistencias a los antibióticos de los microorganismos procedentes de los dos grupos tienen patrones diferentes, siendo globalmente menor a fosfomicina.Objectives: Knowing the results of microbiological tests of urine samples of patients from the Rehabilitation Unit of a regional hospital, including local data of antibiotic susceptibility. Material and methods: We analyzed the database of the Microbiology Laboratory of the Hospital Universitario Virgen de las Nieves with microbiological studies conducted urine samples during 2012. We investigated the etiology and antimicrobial susceptibility of uropathogens frequently present in 143 urine samples. The 9066 survey results voiding urine mean in Primary Care study subjects were used as controls. Results: The 50% of neurological patients had positive urine cultures, versus 23% of controls. E. coli was the most frequently isolated organism group neurological patients, as in the controls. Resistance studies in E. coli showed high rates of resistance to ampicillin, cotrimoxazole, ciprofloxacin and amoxicillin with clavulanic acid. Conclusions: E. coli is the most frequently isolated microorganism in both groups of patients studied. The antibiotic resistance of microorganisms from the two groups have different patterns, being globally less to fosfomycin

Nonlinear, Multicomponent Physical Exercise With Heart Rate Variability-Guided Prescription in Women With Breast Cancer During Treatment: Feasibility and Preliminary Results (ATOPE Study)

The study is funded by the Fondo de Investigación Sanitaria del Instituto de Salud Carlos III and the Fondos Estructurales de la Unión Europea (FEDER) (PI18/01840). Á.G.S. has received funding for its training with the grant FPU18/03575 by the Spanish Ministry of Education Cultura y Deporte. M.L.G. has received funding for its training with the grant FI19/00230 by the Fondo de Investigación Sanitaria del Instituto de Salud Carlos III. R.G.G. has received funding for its training with the grant FPU20/05674 by the Spanish Ministry of Education Cultura y Deporte. Additional funding is provided by the European Regional Development Fund (ERDF, SOMM17/6107/UGR), “Plan Propio de Investigación 2021” University of Granada (PPJIB2021–13) and the Spanish Ministry of Economy and Competitiveness (Plan Estatal de I + D + I 2013–2016).Objective. The purpose of this study was to examine the feasibility, safety, adherence, and preliminary efficacy of the ATOPE program during radiotherapy (RT) or chemotherapy (CT) for women with breast cancer. Methods. This single-blind, pretest–posttest feasibility study included 38 women with breast cancer at the beginning of their treatment. The ATOPE program consisted of 12 to 18 sessions of a multimodal physical exercise program, prescribed based on daily heart rate variability and clinimetric assessments using the ATOPE+ mHealth system. Overall health was assessed with quality of life, autonomous balance, and body composition, whereas health-related fitness was measured through functional capacity, physical activity levels, and upper and lower limb strength. Results. The rates of recruitment, retention, and adherence were 52.35, 73.68, and 84.37%, respectively, and the satisfaction rating was 9.2 out of a possible 10 points. The perceived health status change score was 3.83 points, scored on a −5 to 5 point scale. No adverse effects were found. Compliance results showed that the ATOPE+ mHealth system was used on 73.38% of the days, and the Fitbit bracelet (Google, Mountain View, CA, USA) was used on 84.91% of the days. Women stayed physically active 55% of days. Regarding preliminary results, for overall health, the percentage of body fat in the RT group decreased by 1.93%, whereas it increased by 5.03% in the CT group. Lower limb strength increased in the RT group, specifically knee extensor isometric strength (6.07%), isokinetic knee flexors 180 degree/second (1.53%), and isokinetic knee extensors 300 degree/second (4.53%), in contrast with the reductions found in the CT group (11.07, 18.67, and 14.89%, respectively). Conclusion. The ATOPE program, through nonlinear prescription based on daily monitoring with the ATOPE+ mHealth system, is feasible and safe for application during breast cancer treatment. The results suggest that the overall health can be maintained or even improved regarding most variables. Impact. This study focused on the feasibility, safety, and completion of a physical therapist-led program at early diagnosis for adults with breast cancer. The multimodal, supervised, tailored, nonlinear physical exercise program is feasible and safe, showed a good completion rate, and was able to prevent the quality-of-life deficits that are often triggered by systemic breast cancer treatment. This study highlights the importance of daily morning assessments using the ATOPE+ mHealth system in patients with breast cancer to prescribe nonlinear physical exercise.Fondos Estructurales de la Unión Europea (FEDER) (PI18/01840)Fondo de Investigación Sanitaria del Instituto de Salud Carlos III FI19/00230Spanish Ministry of Education Cultura y Deporte FPU18/03575, FPU20/05674European Regional Development Fund (ERDF, SOMM17/6107/UGR)University of Granada (PPJIB2021–13)Spanish Ministry of Economy and Competitivenes

‘Physio-EndEA’ Study: A Randomized, Parallel-Group Controlled Trial to Evaluate the Effect of a Supervised and Adapted Therapeutic Exercise Program to Improve Quality of Life in Symptomatic Women Diagnosed with Endometriosis

This research was funded by the Health Institute Carlos III (FEDER funds), grant number PI17/01743, and donations from particular endometriosis women that believed in this project from the beginning. It was also partly supported by funds from the PAIDI group CTS-206 (Oncologia Basica y Clinica). This study takes place thanks to the additional funding from the University of Granada, Plan Propio de Investigacion 2016, Excellence actions: Units of Excellence; Unit of Excellence on Exercise and Health (UCEES).Aim: The ‘Physio-EndEA’ study aims to explore the potential benefits of a therapeutic exercise program (focused on lumbopelvic stabilization and tolerance to exertion) on the health-related quality of life (HRQoL) of symptomatic endometriosis women. Design: The present study will use a parallel-group randomized controlled trial design. Methods: A total of 22 symptomatic endometriosis women will be randomized 1:1 to the Physio-EndEA or usual care groups. The ‘Physio-EndEA’ program will consist of a one-week lumbopelvic stabilization learning phase followed by an eight-week phase of stretching, aerobic and resistance exercises focused on the lumbopelvic area that will be sequentially instructed and supervised by a trained physiotherapist (with volume and intensity progression) and adapted daily to the potential of each participant. The primary outcome measure is HRQoL. The secondary outcome measures included clinician-reported outcomes (pressure pain thresholds, muscle thickness and strength, flexibility, body balance and cardiorespiratory fitness) and patient-reported outcomes (pain intensity, physical fitness, chronic fatigue, sexual function, gastrointestinal function and sleep quality). Discussion: Findings of this study will help to identify cost-effective non-pharmacological options (such as this exercise-based intervention) that may contribute to the improvement of HRQoL in symptomatic endometriosis women.Health Institute Carlos III (FEDER funds) PI17/01743PAIDI groupUniversity of Granad

Efectos de la magnetoterapia en líneas celulares humanas de cáncer de mama

Tesis Univ. Granada. Departamento de Radiología y Medicina Físic

Etiology and susceptbility to antimicrobials of urinary tract infections in patients of Rehabilitation Unit of a regional hospital

<p>Objectives: Knowing the results of microbiological tests of urine samples of patients from the Rehabilitation Unit of<br>a regional hospital, including local data of antibiotic susceptibility.<br>Material and methods: We analyzed the database of the Microbiology Laboratory of the Hospital Universitario<br>Virgen de las Nieves with microbiological studies conducted urine samples during 2012. We investigated the etiology<br>and antimicrobial susceptibility of uropathogens frequently present in 143 urine samples. The 9066 survey results<br>voiding urine mean in Primary Care study subjects were used as controls.<br>Results: The 50% of neurological patients had positive urine cultures, versus 23% of controls. E. coli was the most<br>frequently isolated organism group neurological patients, as in the controls. Resistance studies in E. coli showed high<br>rates of resistance to ampicillin, cotrimoxazole, ciprofloxacin and amoxicillin with clavulanic acid.<br>Conclusions: E. coli is the most frequently isolated microorganism in both groups of patients studied. The antibiotic<br>resistance of microorganisms from the two groups have different patterns, being globally less to fosfomycin.</p> <p> </p