A Path Analysis Exploration of Teacher’s Effect, Self-Efficacy, Demographic Factors, and Attitudes toward Mathematics among College Students Attending s Minority Serving Institution in Face-to-Face and Hybrid Mathematics Courses

Graduation rates in colleges and universities have not kept up with the increase in enrollment. Lack of mathematics competence is a factor that impairs students from completing higher education studies. This problem is even more pervasive in minority groups. The existing body of research on mathematics education have not favored emerging minority populations in terms of addressing their needs for academic program completion across mode of instruction. The study analyzed the relationship between type of instruction and the factors underlying students’ attitudes toward mathematics. Further, this study examined the effect of factors underlying the constructs of teacher’s effect and self-efficacy as well as gender and mode of instruction on factors underlying attitudes of students to learn mathematics. Data were collected from a sample of 390 students enrolled in College Algebra delivered in face-to-face and hybrid learning at a minority-serving college, using three well established instruments. A one-way MANOVA and Path Analyses were used to analyze the data. There were significant differences in the level of importance students attributed to learning mathematics for their life in terms of mode of instruction. Those students who learned mathematics in the hybrid setting believed that learning and mastering mathematics would become an advantageous factor for their life. Beliefs of encouragement from the teacher and mathematics capability to solve procedural problems predicted judgments of satisfaction for being enrolled in College Algebra, as well as judgments of the importance students attributed to learning mathematics for their life. Mode of instruction was also a significant predictor of importance. Mathematics apprehension was significantly predicted by discouragement. Perceptions with respect to performing mathematics problems that required applying several procedures was significantly predicted by the combined effect of judgments of encouragement and discouragement from the teacher. Perceptions of being encouraged from the teacher predicted beliefs to perform critical thinking problems in mathematics

An Interaction between the Walker A and D-loop Motifs Is Critical to ATP Hydrolysis and Cooperativity in Bacteriophage T4 Rad50

The ATP binding cassette (ABC) proteins make up a large superfamily with members coming from all kingdoms. The functional form of the ABC protein nucleotide binding domain (NBD) is dimeric with ATP binding sites shared between subunits. The NBD is defined by six motifs: the Walker A, Q-loop, Signature, Walker-B, D-loop, and H-loop. The D-loop contains a conserved aspartate whose function is not clear but has been proposed to be involved in cross-talk between ATP binding sites. Structures of various ABC proteins suggest an interaction between the D-loop aspartate and an asparagine residue located in Walker A loop of the opposing subunit. Here, we evaluate the functional role of the D-loop using a bacteriophage T4 ABC protein, Rad50 (gp46). Mutation of either the D-loop aspartate or the Walker A asparagine results in dramatic reductions in ATP affinity, hydrolysis rate, and cooperativity. The mutant proteins bind Mre11 (gp47) and DNA normally, but no longer support the ATP-dependent nuclease activities of Mre11. We propose that the D-loop aspartate functions to stabilize the Walker A asparagine in a position favorable for catalysis. We find that the asparagine is crucially important to the mechanism of ATP hydrolysis by increasing the affinity for ATP and positioning the γ-phosphate of ATP for catalysis. Additionally, we propose that the asparagine acts as a γ-phosphate sensor and, through its interaction with the conserved D-loop aspartate, transmits conformational changes across the dimer interface to the second ATP binding site

Burden of disease in young population of a colombian health insurance company

To estimate the burden of disease of population between 10-24 years old enrolled in the SER JOVEN program of a Colombian insurance company using disability-adjusted life-years (DALYs). Incidences were estimated from the administrative claims data of Mutual SER EPS. The ICD-10 codes of the main diagnosis were identified and regrouped according to the categories of diseases reported in the global burden of disease (GBD) study. To estimate the years of life lost (YLL), the difference between the age of death and the life expectancy at that age was obtained in a reference mortality population. The years lived with disability (YLD) were obtained by multiplying the estimated morbidity and the disability weights of the GBD 2017. DALYs were calculated by adding YLD and YLLs. We used the information of 512 patients insured to Mutual SER-EPS between 10-24 years, who died during January 2015 to December 2017 from all causes, and the healthcare registers of young people aged 10-24 years residing in 21 municipalities where Mutual SER EPS has presence. In the studied population, premature deaths and disability produced 5,355 DALYs, for 2017. Of these, 67.1% (3,591) of the burden of disease was due to non-communicable causes; followed by communicable, maternal, neonatal, and nutritional diseases (15.9%). The remaining 17% were due to unintentional and vital injuries and unclassified causes. The specific causes with the highest reported burden were substance use disorders and mental disorders, and this relationship remained constant between 2015-2017. In both sexes the first cause was non-communicable diseases; in men, injuries; and in women, communicable, maternal, neonatal diseases. In the analyzed population there was a considerable burden of disease associated with mental disorders and substance use. It is recommended to implement effective strategies that allow prioritizing the diseases that generate the greatest burden

Adherence to long-acting reversible contraceptive methods in low- income young women from the caribbean region of Colombia

Adolescent pregnancies are more likely to occur in poor communities, commonly driven by lack of education and employment opportunities. We aimed to estimate the subdermal implant discontinuation rate and to establish the factors associated with the discontinuation of long-acting reversible contraceptive (LARC) methods in a cohort of poor women in the Caribbean region of Colombia. A retrospective cohort study of LARC method use through review of administrative record data was conducted. A population of 2,192 adolescents and young women between 10-24 years old enrolled in the “SER JOVEN” program and who received subdermal implants between 2015-2018 was considered for eligibility. This program is for young people affiliated to a health care company in the Caribbean region of Colombia. We realized a follow-up time-person of the retrospective cohort, and we estimated the incidence of discontinuation of the subdermal implant at six months, one year, two years, and three years. Kaplan-Meier estimator for survival curves, and Cox proportional hazard model were used to ascertain factors associated with method discontinuation risk. A p-value <0.050 was considered significant. A total of 2,192 women were selected with a mean (standard deviation -SD) age of 19.4 (2.8) years and a mean duration of use of subdermal implant of 2.6 (0.8) years. We estimated the subdermal implant discontinuation rate at six months in 0.7% [CI95% 0.3-1.1], a year later in 1.5% [CI95% 1-2], two years later in 2.1% [CI95% 1.5-2.7] and finally at three years in 2.2% [CI95% 1.6-2.8]. Women who stated they have children at baseline were about 70% less risk to discontinue subdermal implants (HR: 0.3 [CI95% 0.1 – 0.8]). Adolescent pregnancy is a public health problem, and it is an important cause of poverty and illness. Then, the use of subdermal implants is an effective alternative to prevent unintended pregnancies

Associated factors to the control Of cardiovascular risk in a low-income population from the caribbean region of Colombia

To identify associated factors to the control of blood pressure (BP), low-density lipoprotein cholesterol (LDL) and glycated hemoglobin (hba1c) in a low-income population from the Caribbean region of Colombia, enrolled in “De todo corazón -DTC” program between 2013-201

Effectiveness of a cardiovascular disease prevention program in the control of cardiovascular risk factors in a low-income population from the caribbean region of Colombia

To evaluate the effectiveness of a cardiovascular disease prevention program in the control of cardiovascular risk factors in a low-income population from the Caribbean region of Colombi

Effectiveness of a cardiovascular risk management program in reducing the probability of premature death due to cardiovascular events in the Colombian caribbean region

Effectiveness of a cardiovascular risk management program in reducing the probability of premature death due to cardiovascular events in the Colombian Caribbean regio

Estimating the impact of a gender-neutral quadrivalent human papillomavirus vaccination program in all hpv 6/11/16/18 -related diseases in Colombia

We assessed the public health and economic impact of adding males to the existing female-only quadrivalent HPV vaccine (4vHPV) program in Colombia, analyzing different gender-neutral vaccination (GNV) vaccine coverage rates (VCRs). A published HPV-type dynamic transmission model was used to compare female-only vaccination (FOV) versus GNV with two-dose 4vHPV in the 9-10-year-old cohort over a 100-year timeframe in Colombia. The model compared 35% VCR for FOV with GNV at VCRs of 35% (scenario A), 50% (scenario B) and different VCRs between females/males (50%/35%, scenario C). The predicted health outcomes included HPV 6/11/16/18-related disease and deaths averted [cervical intraepithelial neoplasia, cervical, vaginal, vulvar, penile, anal and head and neck cancers, genital warts (GW), and recurrent respiratory papillomatosis], direct healthcare cost prevented by vaccination, and incremental cost-effectiveness ratios (ICERs). All GNV scenarios are estimated to provide faster and greater reductions in HPV 6/11/16/18-related diseases relative to FOV at 35% VCR, mainly scenarios B and C. The highest cumulative reductions in the incidence of HPV 6/11/16/18-related disease and deaths were seen in scenario B relative to FOV at 35% VCR at year 100, averting 28,001 cervical cancer (CC) cases, 11,968 non-CC cases (4,753 in females and 7,215 in males) and 15,141 deaths. The greatest projected reductions in health care costs are due to diseases caused by HPV-6/11 infection, driven by GW. The cost savings varied from 88 (scenario A) to 184 million (scenario B) relative to FOV at 35%. The ICER for all scenarios was <0, indicating that under the model assumptions it is cost-saving to implement a GNV-4vHPV in Colombia. In Colombia, a GNV-4vHPV program is a cost-saving strategy in the three scenarios analyzed relative to the current FOV program and result in greater improvement of the public health and economic impact in both women and men

Impact in hospitalization costs of a cardiovascular risk management program in Colombia: a propensity score matching model

Cardiovascular diseases (CVD) are the leading cause of death and burden of disease in Colombia and globally. In 2017, CVD represented the 12% of total DALYs. CVD is a costly disease from patient, family and societal perspectives. Effective prevention and risk management programs reduces the incidence of CVD by as much as 80%. We aimed to estimate the impact of direct medical hospitalization costs related to adherence in a risk management program in Colombia, 2018. We retrospectively collected data from 6,243 patients with data of enrollment in a cardiovascular risk management program (DTC, in Spanish) of a subsidized insurer, who presented arterial hypertension (AH) or AH+ type 2 diabetes mellitus (DM2). 1,065 were identified adherent to the program (treated) and 5.178 non adherent (controls). We designed a propensity score matching model adjusted with confounding variables to estimate the effect of treatment (program adherence) over hospitalization cost. Costs were calculated based on hospitalization invoices and expressed in Colombian pesos (COP) 2018. DTC has an average negative effect on cost of treated population. Being treated avoids hospitalization costs; these results were statistically significant at the 5% and 10% level (with 95%CI that goes through zero). Hence, being in the DTC program reduces hospital costs that ranges from COP-$11,346,372 to -$ 799,259 (95%CI) compared to the average cost. The overall impact on program costs is a significant saving of COP583,670 per event-year. If all members of the DTC program fulfilled its activities by more than 80%, the savings generated by the program would be close to COP$ 6.85 billion. DTC risk management program reduces direct hospitalization costs of events associated to CVD. Our results are important to design policies focused on the cost and risk management of patients with CVD in poor population

La imagen y la narrativa como herramienta para el abordaje psicosocial en escenarios de violencia. Municipio de Sincelejo

La violencia es un fenómeno que se ha presentado desde tiempos remotos en nuestro país, el dolor, el desplazamiento y las muertes han sido situaciones a las que muchas personas debieron enfrentarse y cargar con una marca que los recuerda toda la vida, el siguiente trabajo tiene como objetivo analizar el relato de una historia donde se evidencia la violencia y el dolor que vivencio una comunidad por parte de los grupos armado, presentar los emergentes psicosociales identificados en el caso, reflexionar alrededor de los significados de la violencia desde la experiencia subjetiva del protagonista e identificar los recurso de afrontamiento y elementos resiliente que se dan en el discurso. A través de preguntas de tipo circular, estratégicas y reflexivas se busca comprender mejor las vivencias de los habitantes, se implementan estrategias que busquen mitigar el impacto que ha generado la violencia en la vida de estas personas, la imagen y la narrativa han sido elementos esenciales que han permitido dar a conocer el proceso de violencia en cada contexto por medio de diferentes descripciones físicas y simbólicas, con este trabajo se pudo identificar emergentes psicosociales los cuales fueron aplicados al análisis de relatos de historias de vidas esperanzadoras en sobrevivientes del conflicto armado en nuestro país, recordando episodios de una violencia que marcó su pasado, pero que hoy por medio del lenguaje se expresan, reflexionan, recuerdan y reconstruyen argumentos significativos e impactantes de la memoria, identificando y reconociendo sus mecanismos de afrontamiento para poder superar la difícil situación vivida.Violence is a phenomenon that has been present since ancient times in our country, pain, displacement and deaths have been situations that many people had to face and carry a mark that remembers them all their lives, the following work has The objective is to analyze the story of a story where the violence and pain experienced by a community by the armed groups is evident, to present the psychosocial emergents identified in the case, to reflect on the meanings of violence from the subjective experience of the protagonist. and identify coping resources and resilient elements that occur in the discourse. Through circular, strategic and reflective questions, the aim is to better understand the experiences of the inhabitants, strategies are implemented that seek to mitigate the impact that violence has generated in the lives of these people, the image and the narrative have been essential elements that have made it possible to publicize the process of violence in each context through different physical and symbolic descriptions, with this work it was possible to identify psychosocial emergents which were applied to the analysis of stories of hopeful lives in survivors of the armed conflict in our country, recalling episodes of violence that marked their past, but that today through language express, reflect, remember and reconstruct significant and powerful arguments from memory, identifying and acknowledging their coping mechanisms in order to overcome the difficult situation experienced