10 research outputs found
Mental health and quality of life of women one year after maternal near-miss in low and middle-income countries: The case of zanzibar, Tanzania
Women who experienced a maternal near-miss are at risk of mental health complications and lower quality of life, but long-term consequences are largely unknown. The aim of this study is to assess whether mental health symptoms and quality of life change over time and to examine associations with risk factors among post-partum women. In this cohort study, women with maternal near-miss were matched to women without or with mild complications at Mnazi Mmoja Hospital in Zanzibar. Depressive and post-traumatic stress disorder symptoms, and quality of life were measured at three, six, and twelve-months follow-up. A linear mixed-effects model was used for data analysis. Postpartum women in Zanzibar reported low levels of depressive and post-traumatic stress disorder symptoms. While depressive symptoms and quality of life trajectories were similar among women with and without maternal near-miss, differences for trajectories of post-traumatic stress disorder symptoms and physical quality of life were found. Social support, perinatal loss, and intercurrent illness were strongly associated with both depressive symptoms and quality of life in this group of Islamic women. These findings suggest that social support, embedded in the cultural context, should be considered in helping women cope with mental health issues in the aftermath of severe maternal complications
Investigating feasibility of 2021 WHO protocol for cervical cancer screening in underscreened populations:PREvention and SCReening Innovation Project Toward Elimination of Cervical Cancer (PRESCRIP-TEC)
Abstract Background High-risk human papillomavirus (hrHPV) testing has been recommended by the World Health Organization as the primary screening test in cervical screening programs. The option of self-sampling for this screening method can potentially increase womenâs participation. Designing screening programs to implement this method among underscreened populations will require contextualized evidence. Methods PREvention and SCReening Innovation Project Toward Elimination of Cervical Cancer (PRESCRIP-TEC) will use a multi-method approach to investigate the feasibility of implementing a cervical cancer screening strategy with hrHPV self-testing as the primary screening test in Bangladesh, India, Slovak Republic and Uganda. The primary outcomes of study include uptake and coverage of the screening program and adherence to follow-up. These outcomes will be evaluated through a pre-post quasi-experimental study design. Secondary objectives of the study include the analysis of client-related factors and health system factors related to cervical cancer screening, a validation study of an artificial intelligence decision support system and an economic evaluation of the screening strategy. Discussion PRESCRIP-TEC aims to provide evidence regarding hrHPV self-testing and the World Health Organizationâs recommendations for cervical cancer screening in a variety of settings, targeting vulnerable groups. The main quantitative findings of the project related to the impact on uptake and coverage of screening will be complemented by qualitative analyses of various determinants of successful implementation of screening. The study will also provide decision-makers with insights into economic aspects of implementing hrHPV self-testing, as well as evaluate the feasibility of using artificial intelligence for task-shifting in visual inspection with acetic acid. Trial registration ClinicalTrials.gov, NCT05234112 . Registered 10 February 202
The Morphology of Galaxies in the Baryon Oscillation Spectroscopic Survey
We study the morphology of luminous and massive galaxies at 0.3<z<0.7
targeted in the Baryon Oscillation Spectroscopic Survey (BOSS) using publicly
available Hubble Space Telescope imaging from COSMOS. Our sample (240 objects)
provides a unique opportunity to check the visual morphology of these galaxies
which were targeted based solely on stellar population modelling. We find that
the majority (74+/-6%) possess an early-type morphology (elliptical or S0),
while the remainder have a late-type morphology. This is as expected from the
goals of the BOSS target selection which aimed to predominantly select slowly
evolving galaxies, for use as cosmological probes, while still obtaining a fair
fraction of actively star forming galaxies for galaxy evolution studies. We
show that a colour cut of (g-i)>2.35 selects a sub-sample of BOSS galaxies with
90% early-type morphology - more comparable to the earlier Luminous Red Galaxy
(LRG) samples of SDSS-I/II. The remaining 10% of galaxies above this cut have a
late-type morphology and may be analogous to the "passive spirals" found at
lower redshift. We find that 23+/-4% of the early-type galaxies are unresolved
multiple systems in the SDSS imaging. We estimate that at least 50% of these
are real associations (not projection effects) and may represent a significant
"dry merger" fraction. We study the SDSS pipeline sizes of BOSS galaxies which
we find to be systematically larger (by 40%) than those measured from HST
images, and provide a statistical correction for the difference. These details
of the BOSS galaxies will help users of the data fine-tune their selection
criteria, dependent on their science applications. For example, the main goal
of BOSS is to measure the cosmic distance scale and expansion rate of the
Universe to percent-level precision - a point where systematic effects due to
the details of target selection may become important.Comment: 18 pages, 11 figures; v2 as accepted by MNRA
Experiences of Pain and Expectations for Its Treatment Among Former Buruli Ulcer Patients
Buruli ulcer (BU) is one of the 17 neglected tropical diseases for which the World Health Organization has adopted resolutions to improve treatment. BU was previously described as a relatively painless condition; however, recent research has indicated that some patients experience substantial pain. The objective of this study was to explore patients' experiences of pain and their expectations for its treatment. Semistructured interviews were conducted in a BU-endemic region of Ghana. Interviews were held with former BU patients (N = 20) and community controls (N = 19). Former patients were asked about BU-related pain and their expectations for its treatment. The interviews were conducted in October 2014, and were audiotaped, translated and transcribed into English, and then qualitatively analyzed. Of the 20 former BU patients interviewed, 19 (95%) reported experiencing pain, with patients reporting pain as a consequence of the ulcer and wound management. Some participants expressed pain through crying, whereas others did not openly express pain, sometimes because they feared the repercussions of doing so. Patients wanted to receive pain relief; however, many were unable to name a medication. Nonpharmaceutical options were cited as being an alternative. Many BU patients experience pain; however, former patients and community members alike appear to have a limited knowledge about available pain relief. A low-cost alternative to medication may be the use of nonpharmaceutical means for pain relief. Routine pain assessment may reduce patients' fear and unwillingness to express pain. Awareness of such issues will be valuable when implementing a BU pain relief guideline
Experiences of Pain and Expectations for Its Treatment Among Former Buruli Ulcer Patients
Assessment and Treatment of Pain during Treatment of Buruli Ulcer Citation for published version (APA): Assessment and Treatment of Pain during Treatment of Buruli Ulcer
Abstract Backgroun
Former Buruli Ulcer Patientsâ Experiences and Wishes May Serve as a Guide to Further Improve Buruli Ulcer Management
<div><p>Background</p><p>Buruli ulcer (BU), caused by <i>Mycobacterium ulcerans</i>, is a neglected tropical disease frequently leading to permanent disabilities. The ulcers are treated with rifampicin and streptomycin, wound care and, if necessary surgical intervention. Professionals have exclusively shaped the research agenda concerning management and control, while patientsâ perspective on priorities and preferences have not explicitly been explored or addressed.</p><p>Methodology/Principal findings</p><p>To get insight into patient perception of the management and control of Buruli ulcer a mixed methods research design was applied with a questionnaire and focus group discussions among former BU patients. Data collection was obtained in collaboration with a local team of native speakers in Ghana. A questionnaire was completed by 60 former patients and four focus group discussions were conducted with eight participants per group. Former patients positively evaluated both the effectiveness of the treatment and the financial contribution received for the travel costs to the hospitals. Pain experienced during treatment procedures, in particular wound care and the streptomycin injections, and the side-effects of the treatment were negatively evaluated. Former patients considered the development of preventive measures and knowledge on the transmission as priorities. Additionally, former patients asked for improved accessibility of health services, counselling and economic support.</p><p>Conclusions</p><p>These findings can be used to improve clinical management and to guide the international research agenda.</p></div
summary of multiple-choice questions analysisâscores represent Likert scales of increasing discomfort with treatment aspects.
<p>summary of multiple-choice questions analysisâscores represent Likert scales of increasing discomfort with treatment aspects.</p