30,737 research outputs found

    Adaptive meshless refinement schemes for RBF-PUM collocation

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    In this paper we present an adaptive discretization technique for solving elliptic partial differential equations via a collocation radial basis function partition of unity method. In particular, we propose a new adaptive scheme based on the construction of an error indicator and a refinement algorithm, which used together turn out to be ad-hoc strategies within this framework. The performance of the adaptive meshless refinement scheme is assessed by numerical tests

    Efficient computation of partition of unity interpolants through a block-based searching technique

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    In this paper we propose a new efficient interpolation tool, extremely suitable for large scattered data sets. The partition of unity method is used and performed by blending Radial Basis Functions (RBFs) as local approximants and using locally supported weight functions. In particular we present a new space-partitioning data structure based on a partition of the underlying generic domain in blocks. This approach allows us to examine only a reduced number of blocks in the search process of the nearest neighbour points, leading to an optimized searching routine. Complexity analysis and numerical experiments in two- and three-dimensional interpolation support our findings. Some applications to geometric modelling are also considered. Moreover, the associated software package written in \textsc{Matlab} is here discussed and made available to the scientific community

    RBF approximation of large datasets by partition of unity and local stabilization

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    We present an algorithm to approximate large dataset by Radial Basis Function (RBF) techniques. The method couples a fast domain decomposition procedure with a localized stabilization method. The resulting algorithm can efficiently deal with large problems and it is robust with respect to the typical instability of kernel methods

    Partition of unity interpolation using stable kernel-based techniques

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    In this paper we propose a new stable and accurate approximation technique which is extremely effective for interpolating large scattered data sets. The Partition of Unity (PU) method is performed considering Radial Basis Functions (RBFs) as local approximants and using locally supported weights. In particular, the approach consists in computing, for each PU subdomain, a stable basis. Such technique, taking advantage of the local scheme, leads to a significant benefit in terms of stability, especially for flat kernels. Furthermore, an optimized searching procedure is applied to build the local stable bases, thus rendering the method more efficient

    Quantum erasure in the presence of a thermal bath: the effects of system-environment microscopic correlations

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    We investigate the role of the environment in a quantum erasure setup in the cavity quantum electrodynamics domain. Two slightly different schemes are analyzed. We show that the effects of the environment vary when a scheme is exchanged for another. This can be used to estimate the macroscopic parameters related to the system-environment microscopic correlations.Comment: 10 pages, 2 figure

    Control of state and state entanglement with a single auxiliary subsystem

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    We present a strategy to control the evolution of a quantum system. The novel aspect of this protocol is the use of a \emph{single auxiliary subsystem}. Two applications are given, one which allows for state preservation and another which controls the degree of entanglement of a given initial state

    MiR-205-5p inhibition by locked nucleic acids impairs metastatic potential of breast cancer cells

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    Mir-205 plays an important role in epithelial biogenesis and in mammary gland development but its role in cancer still remains controversial depending on the specific cellular context and target genes. We have previously reported that miR-205-5p is upregulated in breast cancer stem cells targeting ERBB pathway and leading to targeted therapy resistance. Here we show that miR-205-5p regulates tumorigenic properties of breast cancer cells, as well as epithelial to mesenchymal transition. Silencing this miRNA in breast cancer results in reduced tumor growth and metastatic spreading in mouse models. Moreover, we show that miR-205-5p knock-down can be obtained with the use of specific locked nucleic acids oligonucleotides in vivo suggesting a future potential use of this approach in therapy
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