SÍNDROME DE GRAHAM-LITTLE-PICCARDI-LASSUEUR

Lassueur Graham-Little-Piccardi syndrome is a rare dermatosis of unknown etiology that affects mainly women between 30 and 60 years old. It is characterized by the triad of multifocal scarring alopecia of the scalp, lichenoid follicular eruption and hypotrichosis of axillary and pubic regions. Anatomopathological examination revealed decrease in the number of hair follicles, upper perifollicular infiltrate and areas with fibrosis. Therapy is a challenge, with frequent relapses after local and systemic treatments. We report a typical case of this rare syndrome in a male patient of 46 years.Síndrome de Graham-Little-Piccardi-Lassueur (SGLPL) é uma dermatose rara, de etiologia desconhecida, que acomete principalmente mulheres entre 30 a 60 anos de idade. Caracteriza-se pela tríade de alopecia cicatricial multifocal do couro cabeludo, erupção folicular liquenoide e hipotricose das regiões axilar e pubiana. O exame anatomopatológico revela diminuição do numero dos folículos pilosos, infiltrado perifolicular e fibrose. A terapêutica é um desafio, com recidivas frequentes após tratamentos locais e sistêmicos. Relatamos um caso típico desta síndrome rara, em um paciente sexo masculino de 46 anos

Erythema elevatum diutinum and hypothyroidism: coincidence or causal relationship?

AbstractErythema elevatum diutinum is a rare chronic leukocytoclastic vasculitis of unknown etiology. It is believed to be due to deposition of immune complexes in the vessels. Clinically it is manifested as erythematous violaceous papules and nodules, isolated or confluent with hardened consistency, symmetrical, usually located on the extensor surface of the extremities, particularly over the joints. Diagnosis is based on clinical and histological findings. We report the case of a woman, 71 years old, with erythematous violaceous nodules on the hands, elbows, back and legs, beginning two years ago, with pain and itching. Histopathological analysis revealed leukocytoclastic vasculitis, confirming the clinical suspicion. Laboratory tests revealed hypothyroidism. We report the case because of its rarity, with subsequent review of the literature